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<meta name="DC.Title" content="MR Findings in Spinal Hemangioblastoma: Correlation with Symptoms and with Angiographic and Surgical Findings" />
<meta name="DC.Date" content="2001-01-01" />
<meta name="DC.Publisher" content="American Journal of Neuroradiology" />
<meta name="DC.Rights" content="Copyright © American Society of Neuroradiology" />
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<meta name="DC.Description" content="BACKGROUND AND PURPOSE: To our knowledge, a detailed analysis of MR findings in spinal hemangioblastoma has not been conducted to date. Our purpose was to elucidate the MR features of this disease with special attention to tumor size, correlation with MR findings and clinical symptoms, and any differences between patients with and without von Hippel-Lindau disease (VHLD).

METHODS: MR images in five patients with VHLD and seven patients without VHLD were reviewed retrospectively for spinal hemangioblastoma by two neuroradiologists. The MR findings were correlated with clinical symptoms and with angiographic and surgical findings.

RESULTS: The MR features depended on the size of the spinal hemangioblastoma. Small (10 mm or less) hemangioblastomas were mostly isointense on T1-weighted images, hyperintense on T2-weighted images, and showed homogeneous enhancement. Larger hemangioblastomas tended to be hypointense or mixed hypo- and isointense on T1-weighted images, heterogeneous on T2-weighted images, and tended to show heterogeneous enhancement. Small hemangioblastomas were located at the surface of the spinal cord, most frequently along its posterior aspect. These were subpial in location at surgery and showed well-demarcated, intense enhancement. Symptomatic small hemangioblastomas had relatively large associated syringes, whereas asymptomatic ones did not. A hemangioblastoma larger than 24 mm was invariably accompanied by vascular flow voids. There was no difference in the MR findings between the two patient groups except for the multiplicity and higher percentage of small tumors in patients with VHLD.

CONCLUSION: Knowledge of these MR features helps to differentiate spinal hemangioblastoma from other diseases that show enhancing nodules." />
<meta name="DC.Contributor" content="Bao-Cheng Chu" />
<meta name="DC.Contributor" content="Satoshi Terae" />
<meta name="DC.Contributor" content="Kazutoshi Hida" />
<meta name="DC.Contributor" content="Matakazu Furukawa" />
<meta name="DC.Contributor" content="Satoru Abe" />
<meta name="DC.Contributor" content="Kazuo Miyasaka" />
<meta name="article:published_time" content="2001-01-01" />
<meta name="article:section" content="PEDIATRICS" />
<meta name="citation_title" content="MR Findings in Spinal Hemangioblastoma: Correlation with Symptoms and with Angiographic and Surgical Findings" />
<meta name="citation_abstract" lang="en" content="&lt;p&gt;&lt;i&gt;BACKGROUND AND PURPOSE:&lt;/i&gt; To our knowledge, a detailed analysis of MR findings in spinal hemangioblastoma has not been conducted to date. Our purpose was to elucidate the MR features of this disease with special attention to tumor size, correlation with MR findings and clinical symptoms, and any differences between patients with and without von Hippel-Lindau disease (VHLD).&lt;/p&gt;&lt;p&gt;&lt;i&gt;METHODS:&lt;/i&gt; MR images in five patients with VHLD and seven patients without VHLD were reviewed retrospectively for spinal hemangioblastoma by two neuroradiologists. The MR findings were correlated with clinical symptoms and with angiographic and surgical findings.&lt;/p&gt;&lt;p&gt;&lt;i&gt;RESULTS:&lt;/i&gt; The MR features depended on the size of the spinal hemangioblastoma. Small (10 mm or less) hemangioblastomas were mostly isointense on T1-weighted images, hyperintense on T2-weighted images, and showed homogeneous enhancement. Larger hemangioblastomas tended to be hypointense or mixed hypo- and isointense on T1-weighted images, heterogeneous on T2-weighted images, and tended to show heterogeneous enhancement. Small hemangioblastomas were located at the surface of the spinal cord, most frequently along its posterior aspect. These were subpial in location at surgery and showed well-demarcated, intense enhancement. Symptomatic small hemangioblastomas had relatively large associated syringes, whereas asymptomatic ones did not. A hemangioblastoma larger than 24 mm was invariably accompanied by vascular flow voids. There was no difference in the MR findings between the two patient groups except for the multiplicity and higher percentage of small tumors in patients with VHLD.&lt;/p&gt;&lt;p&gt;&lt;i&gt;CONCLUSION:&lt;/i&gt; Knowledge of these MR features helps to differentiate spinal hemangioblastoma from other diseases that show enhancing nodules.&lt;/p&gt;" />
<meta name="citation_journal_title" content="American Journal of Neuroradiology" />
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<meta name="citation_publication_date" content="2001/01/01" />
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<meta name="citation_author" content="Bao-Cheng Chu" />
<meta name="citation_author" content="Satoshi Terae" />
<meta name="citation_author" content="Kazutoshi Hida" />
<meta name="citation_author" content="Matakazu Furukawa" />
<meta name="citation_author" content="Satoru Abe" />
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<meta name="twitter:title" content="MR Findings in Spinal Hemangioblastoma: Correlation with Symptoms and with Angiographic and Surgical Findings" />
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<meta name="twitter:description" content="BACKGROUND AND PURPOSE: To our knowledge, a detailed analysis of MR findings in spinal hemangioblastoma has not been conducted to date. Our purpose was to elucidate the MR features of this disease with special attention to tumor size, correlation with MR findings and clinical symptoms, and any differences between patients with and without von Hippel-Lindau disease (VHLD).

METHODS: MR images in five patients with VHLD and seven patients without VHLD were reviewed retrospectively for spinal hemangioblastoma by two neuroradiologists. The MR findings were correlated with clinical symptoms and with angiographic and surgical findings.

RESULTS: The MR features depended on the size of the spinal hemangioblastoma. Small (10 mm or less) hemangioblastomas were mostly isointense on T1-weighted images, hyperintense on T2-weighted images, and showed homogeneous enhancement. Larger hemangioblastomas tended to be hypointense or mixed hypo- and isointense on T1-weighted images, heterogeneous on T2-weighted images, and tended to show heterogeneous enhancement. Small hemangioblastomas were located at the surface of the spinal cord, most frequently along its posterior aspect. These were subpial in location at surgery and showed well-demarcated, intense enhancement. Symptomatic small hemangioblastomas had relatively large associated syringes, whereas asymptomatic ones did not. A hemangioblastoma larger than 24 mm was invariably accompanied by vascular flow voids. There was no difference in the MR findings between the two patient groups except for the multiplicity and higher percentage of small tumors in patients with VHLD.

CONCLUSION: Knowledge of these MR features helps to differentiate spinal hemangioblastoma from other diseases that show enhancing nodules." />
<meta name="og-title" property="og:title" content="MR Findings in Spinal Hemangioblastoma: Correlation with Symptoms and with Angiographic and Surgical Findings" />
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<meta name="og-description" property="og:description" content="BACKGROUND AND PURPOSE: To our knowledge, a detailed analysis of MR findings in spinal hemangioblastoma has not been conducted to date. Our purpose was to elucidate the MR features of this disease with special attention to tumor size, correlation with MR findings and clinical symptoms, and any differences between patients with and without von Hippel-Lindau disease (VHLD).

METHODS: MR images in five patients with VHLD and seven patients without VHLD were reviewed retrospectively for spinal hemangioblastoma by two neuroradiologists. The MR findings were correlated with clinical symptoms and with angiographic and surgical findings.

RESULTS: The MR features depended on the size of the spinal hemangioblastoma. Small (10 mm or less) hemangioblastomas were mostly isointense on T1-weighted images, hyperintense on T2-weighted images, and showed homogeneous enhancement. Larger hemangioblastomas tended to be hypointense or mixed hypo- and isointense on T1-weighted images, heterogeneous on T2-weighted images, and tended to show heterogeneous enhancement. Small hemangioblastomas were located at the surface of the spinal cord, most frequently along its posterior aspect. These were subpial in location at surgery and showed well-demarcated, intense enhancement. Symptomatic small hemangioblastomas had relatively large associated syringes, whereas asymptomatic ones did not. A hemangioblastoma larger than 24 mm was invariably accompanied by vascular flow voids. There was no difference in the MR findings between the two patient groups except for the multiplicity and higher percentage of small tumors in patients with VHLD.

CONCLUSION: Knowledge of these MR features helps to differentiate spinal hemangioblastoma from other diseases that show enhancing nodules." />
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        	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-volume highwire-cite-metadata">Vol. 22</span>, <span  class="highwire-cite-metadata-issue highwire-cite-metadata">Issue 1 </span><div  class="highwire-cite-metadata-pubdate highwire-cite-metadata">1 Jan 2001 </div></div>
      
      
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      <div class="highwire-cite-title">MR Findings in Spinal Hemangioblastoma: Correlation with Symptoms and with Angiographic and Surgical Findings</div>  
    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0"><span class="nlm-given-names">Bao-Cheng</span> <span class="nlm-surname">Chu</span></span>, <span class="highwire-citation-author" data-delta="1"><span class="nlm-given-names">Satoshi</span> <span class="nlm-surname">Terae</span></span>, <span class="highwire-citation-author" data-delta="2"><span class="nlm-given-names">Kazutoshi</span> <span class="nlm-surname">Hida</span></span>, <span class="highwire-citation-author" data-delta="3"><span class="nlm-given-names">Matakazu</span> <span class="nlm-surname">Furukawa</span></span>, <span class="highwire-citation-author" data-delta="4"><span class="nlm-given-names">Satoru</span> <span class="nlm-surname">Abe</span></span>, <span class="highwire-citation-author" data-delta="5"><span class="nlm-given-names">Kazuo</span> <span class="nlm-surname">Miyasaka</span></span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">Jan 2001, </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">22 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(1) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">206-217; </span></div>
  
  
  
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      <div class="highwire-cite-title">MR Findings in Spinal Hemangioblastoma: Correlation with Symptoms and with Angiographic and Surgical Findings</div>  
    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0"><span class="nlm-given-names">Bao-Cheng</span> <span class="nlm-surname">Chu</span></span>, <span class="highwire-citation-author" data-delta="1"><span class="nlm-given-names">Satoshi</span> <span class="nlm-surname">Terae</span></span>, <span class="highwire-citation-author" data-delta="2"><span class="nlm-given-names">Kazutoshi</span> <span class="nlm-surname">Hida</span></span>, <span class="highwire-citation-author" data-delta="3"><span class="nlm-given-names">Matakazu</span> <span class="nlm-surname">Furukawa</span></span>, <span class="highwire-citation-author" data-delta="4"><span class="nlm-given-names">Satoru</span> <span class="nlm-surname">Abe</span></span>, <span class="highwire-citation-author" data-delta="5"><span class="nlm-given-names">Kazuo</span> <span class="nlm-surname">Miyasaka</span></span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">Jan 2001, </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">22 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(1) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">206-217; </span></div>
  
  
  
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