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<meta name="DC.Title" content="T1-Weighted Fluid-Attenuated Inversion Recovery at Low Field Strength: A Viable Alternative for T1-Weighted Intracranial Imaging" />
<meta name="DC.Date" content="2003-04-01" />
<meta name="DC.Publisher" content="American Journal of Neuroradiology" />
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<meta name="DC.Description" content="BACKGROUND AND PURPOSE: T1-weighted spin-echo imaging has been widely used to study anatomic detail and abnormalities of the brain; however, the image contrast of this technique is often poor, especially at low field strengths. We tested a new pulse sequence, T1-weighted fluid-attenuated inversion recovery (FLAIR), which provides good contrast between lesions, surrounding edematous tissue, and normal parenchyma at low field strengths and at acquisition times comparable to those of T1-weighted spin-echo imaging.

METHODS: Thirteen patients with brain lesions underwent T1-weighted spin-echo and T1-weighted FLAIR imaging during the same imaging session. T1-weighted spin-echo and T1-weighted FLAIR images were compared on the basis of four quantitative (lesion-white matter [WM] contrast-to-noise ratio [CNR], lesion-CSF CNR, gray matter-WM CNR, and WM-CSF CNR) and three qualitative criteria (conspicuousness of lesions, image artifacts, and overall image contrast).

RESULTS: CNRs obtained with T1-weighted FLAIR were comparable but statistically superior to those obtained with T1-weighted spin-echo imaging. In general, T1-weighted FLAIR and T1-weighted spin-echo imaging produced comparable image artifacts. Conspicuousness of lesions and the overall image contrast were judged to be superior on T1-weighted FLAIR images.

CONCLUSION: T1-weighted FLAIR imaging may be a valuable alternative to conventional T1-weighted imaging, because the former technique offers superior image contrast at low field strengths and comparable acquisition times." />
<meta name="DC.Contributor" content="Masaaki Hori" />
<meta name="DC.Contributor" content="Toshiyuki Okubo" />
<meta name="DC.Contributor" content="Kazuhito Uozumi" />
<meta name="DC.Contributor" content="Keiichi Ishigame" />
<meta name="DC.Contributor" content="Hiroshi Kumagai" />
<meta name="DC.Contributor" content="Tsutomu Araki" />
<meta name="article:published_time" content="2003-04-01" />
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<meta name="citation_title" content="T1-Weighted Fluid-Attenuated Inversion Recovery at Low Field Strength: A Viable Alternative for T1-Weighted Intracranial Imaging" />
<meta name="citation_abstract" lang="en" content="&lt;p&gt;&lt;i&gt;BACKGROUND AND PURPOSE:&lt;/i&gt; T1-weighted spin-echo imaging has been widely used to study anatomic detail and abnormalities of the brain; however, the image contrast of this technique is often poor, especially at low field strengths. We tested a new pulse sequence, T1-weighted fluid-attenuated inversion recovery (FLAIR), which provides good contrast between lesions, surrounding edematous tissue, and normal parenchyma at low field strengths and at acquisition times comparable to those of T1-weighted spin-echo imaging.&lt;/p&gt;&lt;p&gt;&lt;i&gt;METHODS:&lt;/i&gt; Thirteen patients with brain lesions underwent T1-weighted spin-echo and T1-weighted FLAIR imaging during the same imaging session. T1-weighted spin-echo and T1-weighted FLAIR images were compared on the basis of four quantitative (lesion-white matter [WM] contrast-to-noise ratio [CNR], lesion-CSF CNR, gray matter-WM CNR, and WM-CSF CNR) and three qualitative criteria (conspicuousness of lesions, image artifacts, and overall image contrast).&lt;/p&gt;&lt;p&gt;&lt;i&gt;RESULTS:&lt;/i&gt; CNRs obtained with T1-weighted FLAIR were comparable but statistically superior to those obtained with T1-weighted spin-echo imaging. In general, T1-weighted FLAIR and T1-weighted spin-echo imaging produced comparable image artifacts. Conspicuousness of lesions and the overall image contrast were judged to be superior on T1-weighted FLAIR images.&lt;/p&gt;&lt;p&gt;&lt;i&gt;CONCLUSION:&lt;/i&gt; T1-weighted FLAIR imaging may be a valuable alternative to conventional T1-weighted imaging, because the former technique offers superior image contrast at low field strengths and comparable acquisition times.&lt;/p&gt;" />
<meta name="citation_journal_title" content="American Journal of Neuroradiology" />
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<meta name="citation_author" content="Masaaki Hori" />
<meta name="citation_author" content="Toshiyuki Okubo" />
<meta name="citation_author" content="Kazuhito Uozumi" />
<meta name="citation_author" content="Keiichi Ishigame" />
<meta name="citation_author" content="Hiroshi Kumagai" />
<meta name="citation_author" content="Tsutomu Araki" />
<meta name="twitter:title" content="T1-Weighted Fluid-Attenuated Inversion Recovery at Low Field Strength: A Viable Alternative for T1-Weighted Intracranial Imaging" />
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<meta name="twitter:description" content="BACKGROUND AND PURPOSE: T1-weighted spin-echo imaging has been widely used to study anatomic detail and abnormalities of the brain; however, the image contrast of this technique is often poor, especially at low field strengths. We tested a new pulse sequence, T1-weighted fluid-attenuated inversion recovery (FLAIR), which provides good contrast between lesions, surrounding edematous tissue, and normal parenchyma at low field strengths and at acquisition times comparable to those of T1-weighted spin-echo imaging.

METHODS: Thirteen patients with brain lesions underwent T1-weighted spin-echo and T1-weighted FLAIR imaging during the same imaging session. T1-weighted spin-echo and T1-weighted FLAIR images were compared on the basis of four quantitative (lesion-white matter [WM] contrast-to-noise ratio [CNR], lesion-CSF CNR, gray matter-WM CNR, and WM-CSF CNR) and three qualitative criteria (conspicuousness of lesions, image artifacts, and overall image contrast).

RESULTS: CNRs obtained with T1-weighted FLAIR were comparable but statistically superior to those obtained with T1-weighted spin-echo imaging. In general, T1-weighted FLAIR and T1-weighted spin-echo imaging produced comparable image artifacts. Conspicuousness of lesions and the overall image contrast were judged to be superior on T1-weighted FLAIR images.

CONCLUSION: T1-weighted FLAIR imaging may be a valuable alternative to conventional T1-weighted imaging, because the former technique offers superior image contrast at low field strengths and comparable acquisition times." />
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<meta name="og-description" property="og:description" content="BACKGROUND AND PURPOSE: T1-weighted spin-echo imaging has been widely used to study anatomic detail and abnormalities of the brain; however, the image contrast of this technique is often poor, especially at low field strengths. We tested a new pulse sequence, T1-weighted fluid-attenuated inversion recovery (FLAIR), which provides good contrast between lesions, surrounding edematous tissue, and normal parenchyma at low field strengths and at acquisition times comparable to those of T1-weighted spin-echo imaging.

METHODS: Thirteen patients with brain lesions underwent T1-weighted spin-echo and T1-weighted FLAIR imaging during the same imaging session. T1-weighted spin-echo and T1-weighted FLAIR images were compared on the basis of four quantitative (lesion-white matter [WM] contrast-to-noise ratio [CNR], lesion-CSF CNR, gray matter-WM CNR, and WM-CSF CNR) and three qualitative criteria (conspicuousness of lesions, image artifacts, and overall image contrast).

RESULTS: CNRs obtained with T1-weighted FLAIR were comparable but statistically superior to those obtained with T1-weighted spin-echo imaging. In general, T1-weighted FLAIR and T1-weighted spin-echo imaging produced comparable image artifacts. Conspicuousness of lesions and the overall image contrast were judged to be superior on T1-weighted FLAIR images.

CONCLUSION: T1-weighted FLAIR imaging may be a valuable alternative to conventional T1-weighted imaging, because the former technique offers superior image contrast at low field strengths and comparable acquisition times." />
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    <title>T1-Weighted Fluid-Attenuated Inversion Recovery at Low Field Strength: A Viable Alternative for T1-Weighted Intracranial Imaging | American Journal of Neuroradiology</title>  
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    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">April 2003,  </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">24 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(4) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">648-651; </span></div>
  
  
  
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    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">Apr 2003, </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">24 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(4) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">648-651; </span></div>
  
  
  
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