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<meta name="DC.Title" content="Disruption of Cerebellar Development: Potential Complication of Extreme Prematurity" />
<meta name="DC.Date" content="2005-08-01" />
<meta name="DC.Publisher" content="American Journal of Neuroradiology" />
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<meta name="DC.Description" content="BACKGROUND AND PURPOSE: Infants with very low birth weight are at high risk for cerebral lesions. Although supratentorial brain damage is a common radiologic finding, posterior fossa pathologies are rare. We studied the morphology of cerebellar involvement in a large series of 28 premature infants born before the 30th week of gestation to define typical patterns and identify possible risk factors for this pathology.

METHODS: Cranial sonograms were obtained in the early neonatal period. MR imaging was performed between the 2nd month and the 6th year of life. Morphologic patterns of cerebellar involvement were evaluated.

RESULTS: Three morphologic patterns of cerebellar involvement were recognized: (1) symmetric volume reduction of the cerebellar hemispheres, which were floating immediately beneath the tentorium, and a small vermis with preserved shape; (2) symmetrical reduction in hemispheric volume with an enlarged, balloon-shaped fourth ventricle and a small, deformed vermis; and (3) normal overall cerebellar shape with extensive reduction of its dimensions. A small brain stem with flattened anterior curvature of the pons and loss of supratentorial white matter was present in all patients.

CONCLUSION: Symmetric cerebellar volume reduction was found as a consequence of extreme prematurity. Selective vulnerability of the developing cerebellum in the window of 24–30 weeks of gestation, combined with several additive perinatal risk factors (eg, hemosiderin deposits) seems to lead to destruction of immature structures and developmental arrest. Therefore, the resulting condition is the consequence of disrupted cerebellar development." />
<meta name="DC.Contributor" content="Agnes Messerschmidt" />
<meta name="DC.Contributor" content="Peter C. Brugger" />
<meta name="DC.Contributor" content="Eugen Boltshauser" />
<meta name="DC.Contributor" content="Gerlinde Zoder" />
<meta name="DC.Contributor" content="Walter Sterniste" />
<meta name="DC.Contributor" content="Robert Birnbacher" />
<meta name="DC.Contributor" content="Daniela Prayer" />
<meta name="article:published_time" content="2005-08-01" />
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<meta name="citation_title" content="Disruption of Cerebellar Development: Potential Complication of Extreme Prematurity" />
<meta name="citation_abstract" lang="en" content="&lt;p&gt;&lt;i&gt;BACKGROUND AND PURPOSE:&lt;/i&gt; Infants with very low birth weight are at high risk for cerebral lesions. Although supratentorial brain damage is a common radiologic finding, posterior fossa pathologies are rare. We studied the morphology of cerebellar involvement in a large series of 28 premature infants born before the 30th week of gestation to define typical patterns and identify possible risk factors for this pathology.&lt;/p&gt;&lt;p&gt;&lt;i&gt;METHODS:&lt;/i&gt; Cranial sonograms were obtained in the early neonatal period. MR imaging was performed between the 2nd month and the 6th year of life. Morphologic patterns of cerebellar involvement were evaluated.&lt;/p&gt;&lt;p&gt;&lt;i&gt;RESULTS:&lt;/i&gt; Three morphologic patterns of cerebellar involvement were recognized: (1) symmetric volume reduction of the cerebellar hemispheres, which were floating immediately beneath the tentorium, and a small vermis with preserved shape; (2) symmetrical reduction in hemispheric volume with an enlarged, balloon-shaped fourth ventricle and a small, deformed vermis; and (3) normal overall cerebellar shape with extensive reduction of its dimensions. A small brain stem with flattened anterior curvature of the pons and loss of supratentorial white matter was present in all patients.&lt;/p&gt;&lt;p&gt;&lt;i&gt;CONCLUSION:&lt;/i&gt; Symmetric cerebellar volume reduction was found as a consequence of extreme prematurity. Selective vulnerability of the developing cerebellum in the window of 24–30 weeks of gestation, combined with several additive perinatal risk factors (eg, hemosiderin deposits) seems to lead to destruction of immature structures and developmental arrest. Therefore, the resulting condition is the consequence of disrupted cerebellar development.&lt;/p&gt;" />
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<meta name="citation_reference" content="citation_title=Brain research;citation_journal_abbrev=Brain Res;citation_title=Neuronal migration, with special reference to developing human brain: a review.;citation_pages=1-35;citation_volume=62;citation_year=1973;citation_issue=1;citation_pmid=4203033;citation_doi=10.1016/0006-8993(73)90617-3" />
<meta name="citation_reference" content="citation_title=The Journal of comparative neurology;citation_journal_abbrev=J Comp Neurol;citation_title=Neuron-glia relationship during granule cell migration in developing cerebellar cortex. A Golgi and electronmicroscopic study in Macacus Rhesus.;citation_pages=283-312;citation_volume=141;citation_year=1971;citation_issue=3;citation_pmid=4101340;citation_doi=10.1002/cne.901410303" />
<meta name="citation_reference" content="citation_title=The Journal of comparative neurology;citation_journal_abbrev=J Comp Neurol;citation_title=Histogenesis of cortical layers in human cerebellum, particularly the lamina dissecans.;citation_pages=473-500;citation_volume=139;citation_year=1970;citation_issue=4;citation_pmid=4195699;citation_doi=10.1002/cne.901390407" />
<meta name="citation_reference" content="citation_title=Journal of neurology;citation_journal_abbrev=J Neurol;citation_title=Development and developmental disorders of the human cerebellum.;citation_pages=1025-1036;citation_volume=250;citation_year=2003;citation_issue=9;citation_pmid=14504962;citation_doi=10.1007/s00415-003-0199-9" />
<meta name="citation_reference" content="citation_title=Acta neuropathologica;citation_journal_abbrev=Acta Neuropathol (Berl);citation_title=Development of Purkinje cells in humans: an immunohistochemical study using a monoclonal antibody against the inositol 1,4,5-triphosphate type 1 receptor (IP3R1).;citation_pages=226-232;citation_volume=98;citation_year=1999;citation_issue=3;citation_pmid=10483778;citation_doi=10.1007/s004010051073" />
<meta name="citation_reference" content="citation_title=Brain research;citation_journal_abbrev=Brain Res;citation_title=Cerebellar alterations induced by chronic hypoxia: an immunohistochemical study using a chick embryonic model.;citation_pages=271-276;citation_volume=901;citation_year=2001;citation_issue=1-2;citation_pmid=11368977;citation_doi=10.1016/S0006-8993(01)02362-9" />
<meta name="citation_reference" content="citation_title=Journal of Neuroscience;citation_journal_abbrev=J. Neurosci.;citation_title=Molecular plasticity of adult Bergmann fibers is associated with radial migration of grafted Purkinje cells;citation_pages=124-133;citation_volume=14;citation_year=1994;citation_issue=1;citation_issn=0270-6474;citation_pmid=8283229" />
<meta name="citation_reference" content="citation_title=Early human development;citation_journal_abbrev=Early Hum Dev;citation_title=The differences in growth of cerebellar vermis between appropriate-for-gestational-age and small-for-gestational-age newborns.;citation_pages=9-19;citation_volume=33;citation_year=1993;citation_issue=1;citation_pmid=8319557;citation_doi=10.1016/0378-3782(93)90169-U" />
<meta name="citation_reference" content="citation_title=Brain &amp; development;citation_journal_abbrev=Brain Dev;citation_title=Neurotransmitters and vulnerability of the developing brain.;citation_pages=301-306;citation_volume=17;citation_year=1995;citation_issue=5;citation_pmid=8579213;citation_doi=10.1016/0387-7604(95)00079-Q" />
<meta name="citation_reference" content="citation_title=Mental retardation and developmental disabilities research reviews;citation_journal_abbrev=Ment Retard Dev Disabil Res Rev;citation_title=Excitotoxicity in neonatal hypoxia.;citation_pages=229-234;citation_volume=7;citation_year=2001;citation_issue=4;citation_pmid=11754516;citation_doi=10.1002/mrdd.1032" />
<meta name="citation_reference" content="citation_title=The Neuroscientist;citation_journal_abbrev=Neuroscientist;citation_title=Mechanisms of Hypoxic Neurodegeneration in the Developing Brain;citation_pages=212-220;citation_volume=8;citation_year=2002;citation_issue=3;citation_issn=1073-8584;citation_pmid=12061501;citation_doi=10.1177/1073858402008003007" />
<meta name="citation_reference" content="citation_title=Biology of the neonate;citation_journal_abbrev=Biol Neonate;citation_title=Can adverse neonatal experiences alter brain development and subsequent behavior?;citation_pages=69-82;citation_volume=77;citation_year=2000;citation_issue=2;citation_pmid=10657682;citation_doi=10.1159/000014197" />
<meta name="citation_reference" content="citation_title=Clinics in perinatology;citation_journal_abbrev=Clin Perinatol;citation_title=Vulnerability of the developing brain. Neuronal mechanisms.;citation_pages=357-372;citation_volume=29;citation_year=2002;citation_issue=3;citation_pmid=12380463;citation_doi=10.1016/S0095-5108(02)00011-8" />
<meta name="citation_reference" content="citation_title=Pediatric neurology;citation_journal_abbrev=Pediatr Neurol;citation_title=Glutamate transporters in neonatal cerebellar subarachnoid hemorrhage.;citation_pages=42-48;citation_volume=23;citation_year=2000;citation_issue=1;citation_pmid=10963969;citation_doi=10.1016/S0887-8994(00)00142-9" />
<meta name="citation_reference" content="citation_title=Brain &amp; development;citation_journal_abbrev=Brain Dev;citation_title=Pontocerebellar hypoplasias. An overview of a group of inherited neurodegenerative disorders with fetal onset.;citation_pages=411-422;citation_volume=15;citation_year=1993;citation_issue=6;citation_pmid=8147499;citation_doi=10.1016/0387-7604(93)90080-R" />
<meta name="citation_reference" content="citation_title=Archives of Neurology;citation_journal_abbrev=Arch Neurol;citation_title=Human Cerebellar Hypoplasia: A Syndrome of Diverse Causes;citation_pages=300-305;citation_volume=37;citation_year=1980;citation_issue=5;citation_issn=0003-9942;citation_pmid=7387451;citation_doi=10.1001/archneur.1980.00500540078012" />
<meta name="citation_reference" content="citation_title=Anatomy and embryology;citation_journal_abbrev=Anat Embryol (Berl);citation_title=Reactive gliosis of immature Bergmann glia and microglial cell activation in response to cell death of granule cell precursors induced by methylazoxymethanol treatment in developing rat cerebellum.;citation_pages=111-122;citation_volume=198;citation_year=1998;citation_issue=2;citation_pmid=9725770;citation_doi=10.1007/s004290050169" />
<meta name="citation_reference" content="citation_title=Rinshō shinkeigaku = Clinical neurology;citation_journal_abbrev=Rinsho Shinkeigaku;citation_title=[Two cases of superficial siderosis of the central nervous system. Findings of the cerebrospinal fluid, magnetic resonance imaging and positron emission tomography];citation_pages=1125-1130;citation_volume=35;citation_year=1995;citation_issue=10;citation_pmid=8821497" />
<meta name="citation_reference" content="citation_title=Neuroradiology;citation_journal_abbrev=Neuroradiology;citation_title=Superficial siderosis of the brain following unexplained subarachnoid hemorrhage: MRI diagnosis and clinical significance.;citation_pages=407-410;citation_volume=34;citation_year=1992;citation_issue=5;citation_pmid=1407522;citation_doi=10.1007/BF00596502" />
<meta name="citation_reference" content="citation_title=Acta neuropathologica;citation_journal_abbrev=Acta Neuropathol (Berl);citation_title=Superficial siderosis of the central nervous system. A report on nine cases with autopsy.;citation_pages=56-74;citation_volume=13;citation_year=1969;citation_issue=1;citation_pmid=5784099;citation_doi=10.1007/BF00686141" />
<meta name="citation_reference" content="citation_title=Child’s Nerv Syst;citation_pages=263;citation_volume=17;citation_year=2001;citation_doi=10.1007/s003810000411" />
<meta name="citation_reference" content="citation_title=Developmental Neuropathology.;citation_pages=108;citation_volume=1989" />
<meta name="citation_reference" content="citation_title=Brain &amp; development;citation_journal_abbrev=Brain Dev;citation_title=Glial reaction in periventricular areas of the brainstem in fetal and neonatal posthemorrhagic hydrocephalus and congenital hydrocephalus.;citation_pages=40-45;citation_volume=18;citation_year=1996;citation_issue=1;citation_pmid=8907341;citation_doi=10.1016/0387-7604(95)00107-7" />
<meta name="citation_reference" content="citation_title=Pediatric neurology;citation_journal_abbrev=Pediatr Neurol;citation_title=Neonatal posthemorrhagic hydrocephalus: neuropathologic and immunohistochemical studies.;citation_pages=230-234;citation_volume=13;citation_year=1995;citation_issue=3;citation_pmid=8554660;citation_doi=10.1016/0887-8994(95)00183-G" />
<meta name="citation_reference" content="citation_title=Brain research bulletin;citation_journal_abbrev=Brain Res Bull;citation_title=Iron and neurodegenerative disorders.;citation_pages=155-164;citation_volume=55;citation_year=2001;citation_issue=2;citation_pmid=11470311;citation_doi=10.1016/S0361-9230(01)00510-X" />
<meta name="citation_reference" content="citation_title=Archives of Disease in Childhood;citation_journal_abbrev=Arch. Dis. Child.;citation_title=Increased plasma malondialdehyde associated with cerebellar structural defects;citation_pages=231-234;citation_volume=77;citation_year=1997;citation_issue=3;citation_issn=0003-9888;citation_pmid=9370902" />
<meta name="citation_reference" content="citation_title=Journal of neuroradiology.  Journal de neuroradiologie;citation_journal_abbrev=J Neuroradiol;citation_title=Cystic malformations of the posterior fossa. Abnormalities associated with the development of the roof of the fourth ventricle and adjacent meningeal structures.;citation_pages=103-133;citation_volume=9;citation_year=1982;citation_issue=2;citation_pmid=7108588;citation_doi=10.1007/BF00341428" />
<meta name="citation_reference" content="citation_title=Pediatric neuroimaging.;citation_pages=251;citation_year=2000" />
<meta name="citation_reference" content="citation_title=American Journal of Neuroradiology;citation_journal_abbrev=Am. J. Neuroradiol.;citation_title=Analysis and Classification of Cerebellar Malformations;citation_pages=1074-1087;citation_volume=23;citation_year=2002;citation_issue=7;citation_issn=0195-6108;citation_pmid=12169461" />
<meta name="citation_reference" content="citation_title=Neuropediatrics;citation_journal_abbrev=Neuropediatrics;citation_title=Clinical spectrum and diagnostic difficulties of infantile ponto-cerebellar hypoplasia type 1.;citation_pages=243-248;citation_volume=30;citation_year=1999;citation_issue=5;citation_pmid=10598835" />
<meta name="citation_reference" content="citation_title=MRI of the fetal brain: normal development and cerebral pathologies.;citation_pages=217;citation_year=2004" />
<meta name="citation_reference" content="citation_title=Pediatric radiology;citation_journal_abbrev=Pediatr Radiol;citation_title=Pontoneocerebellar hypoplasia: definition of MR features.;citation_pages=613-618;citation_volume=31;citation_year=2001;citation_issue=9;citation_pmid=11511999;citation_doi=10.1007/s002470100507" />
<meta name="citation_reference" content="citation_title=Child’s Nerv Syst;citation_pages=642;citation_volume=13;citation_year=1997;citation_doi=10.1007/s003810050161" />
<meta name="citation_reference" content="citation_title=Clinical neuropathology;citation_journal_abbrev=Clin Neuropathol;citation_title=Pontoneocerebellar hypoplasia--a probable consequence of prenatal destruction of the pontine nuclei and a possible role of phenytoin intoxication.;citation_pages=160-167;citation_volume=3;citation_year=1984;citation_issue=4;citation_pmid=6478678" />
<meta name="citation_reference" content="citation_title=Developmental medicine and child neurology;citation_journal_abbrev=Dev Med Child Neurol;citation_title=Neocerebellar hypoplasia in a neonate following intra-uterine exposure to anticonvulsants.;citation_pages=737-742;citation_volume=32;citation_year=1990;citation_issue=8;citation_pmid=2210089" />
<meta name="citation_reference" content="citation_title=Neuroradiology;citation_journal_abbrev=Neuroradiology;citation_title=Congenital pontocerebellar atrophy in three patients: clinical, radiologic and etiologic considerations.;citation_pages=684-687;citation_volume=38;citation_year=1996;citation_issue=7;citation_pmid=8912329;citation_doi=10.1007/s002340050334" />
<meta name="citation_reference" content="citation_title=Neuroradiology;citation_journal_abbrev=Neuroradiology;citation_title=MRI in cerebellar hypoplasia.;citation_pages=148-151;citation_volume=36;citation_year=1994;citation_issue=2;citation_pmid=8183459;citation_doi=10.1007/BF00588085" />
<meta name="citation_reference" content="citation_title=Neurology;citation_journal_abbrev=Neurology;citation_title=The syndrome of autosornal recessive pontocerebellar hypoplasia, microcephaly, and extrapyramidal dyskinesia (pontocerebellar hypoplasia type 2): Compiled data from 10 pedigrees;citation_pages=311-317;citation_volume=45;citation_year=1995;citation_issue=2;citation_issn=0028-3878;citation_pmid=7854532" />
<meta name="citation_reference" content="citation_title=Journal of Child Neurology;citation_journal_abbrev=J Child Neurol;citation_title=Pontocerebellar Hypoplasia Type 1: New Leads for an Earlier Diagnosis;citation_pages=220-225;citation_volume=18;citation_year=2003;citation_issue=3;citation_issn=0883-0738;citation_pmid=12731647;citation_doi=10.1177/08830738030180031201" />
<meta name="citation_reference" content="citation_title=Am J Med Genet;citation_pages=211;citation_volume=123A;citation_year=2003" />
<meta name="citation_reference" content="citation_title=The Journal of pediatrics;citation_journal_abbrev=J Pediatr;citation_title=Errors of morphogenesis: concepts and terms. Recommendations of an international working group.;citation_pages=160-165;citation_volume=100;citation_year=1982;citation_issue=1;citation_pmid=7057306;citation_doi=10.1016/S0022-3476(82)80261-8" />
<meta name="twitter:title" content="Disruption of Cerebellar Development: Potential Complication of Extreme Prematurity" />
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<meta name="twitter:description" content="BACKGROUND AND PURPOSE: Infants with very low birth weight are at high risk for cerebral lesions. Although supratentorial brain damage is a common radiologic finding, posterior fossa pathologies are rare. We studied the morphology of cerebellar involvement in a large series of 28 premature infants born before the 30th week of gestation to define typical patterns and identify possible risk factors for this pathology.

METHODS: Cranial sonograms were obtained in the early neonatal period. MR imaging was performed between the 2nd month and the 6th year of life. Morphologic patterns of cerebellar involvement were evaluated.

RESULTS: Three morphologic patterns of cerebellar involvement were recognized: (1) symmetric volume reduction of the cerebellar hemispheres, which were floating immediately beneath the tentorium, and a small vermis with preserved shape; (2) symmetrical reduction in hemispheric volume with an enlarged, balloon-shaped fourth ventricle and a small, deformed vermis; and (3) normal overall cerebellar shape with extensive reduction of its dimensions. A small brain stem with flattened anterior curvature of the pons and loss of supratentorial white matter was present in all patients.

CONCLUSION: Symmetric cerebellar volume reduction was found as a consequence of extreme prematurity. Selective vulnerability of the developing cerebellum in the window of 24–30 weeks of gestation, combined with several additive perinatal risk factors (eg, hemosiderin deposits) seems to lead to destruction of immature structures and developmental arrest. Therefore, the resulting condition is the consequence of disrupted cerebellar development." />
<meta name="og-title" property="og:title" content="Disruption of Cerebellar Development: Potential Complication of Extreme Prematurity" />
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<meta name="og-description" property="og:description" content="BACKGROUND AND PURPOSE: Infants with very low birth weight are at high risk for cerebral lesions. Although supratentorial brain damage is a common radiologic finding, posterior fossa pathologies are rare. We studied the morphology of cerebellar involvement in a large series of 28 premature infants born before the 30th week of gestation to define typical patterns and identify possible risk factors for this pathology.

METHODS: Cranial sonograms were obtained in the early neonatal period. MR imaging was performed between the 2nd month and the 6th year of life. Morphologic patterns of cerebellar involvement were evaluated.

RESULTS: Three morphologic patterns of cerebellar involvement were recognized: (1) symmetric volume reduction of the cerebellar hemispheres, which were floating immediately beneath the tentorium, and a small vermis with preserved shape; (2) symmetrical reduction in hemispheric volume with an enlarged, balloon-shaped fourth ventricle and a small, deformed vermis; and (3) normal overall cerebellar shape with extensive reduction of its dimensions. A small brain stem with flattened anterior curvature of the pons and loss of supratentorial white matter was present in all patients.

CONCLUSION: Symmetric cerebellar volume reduction was found as a consequence of extreme prematurity. Selective vulnerability of the developing cerebellum in the window of 24–30 weeks of gestation, combined with several additive perinatal risk factors (eg, hemosiderin deposits) seems to lead to destruction of immature structures and developmental arrest. Therefore, the resulting condition is the consequence of disrupted cerebellar development." />
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      <h1 class="highwire-cite-title" id="page-title">Disruption of Cerebellar Development: Potential Complication of Extreme Prematurity</h1>  
    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0">Agnes Messerschmidt</span>, <span class="highwire-citation-author" data-delta="1">Peter C. Brugger</span>, <span class="highwire-citation-author" data-delta="2">Eugen Boltshauser</span>, <span class="highwire-citation-author" data-delta="3">Gerlinde Zoder</span>, <span class="highwire-citation-author" data-delta="4">Walter Sterniste</span>, <span class="highwire-citation-author" data-delta="5">Robert Birnbacher</span> and <span class="highwire-citation-author" data-delta="6">Daniela Prayer</span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">August 2005,  </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">26 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(7) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">1659-1667; </span></div>
  
  
  
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