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<meta name="DC.Title" content="Intracranial Angioplasty and Stenting: Long-Term Results from a Single Center" />
<meta name="DC.Date" content="2006-10-01" />
<meta name="DC.Publisher" content="American Journal of Neuroradiology" />
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<meta name="DC.Description" content="BACKGROUND AND PURPOSE: Large-vessel intracranial atherosclerotic stenosis carries a proved stroke risk of 8%–22% per year with “best medical therapy.” The long-term clinical neurologic and angiographic outcomes of angioplasty and/or stent placement for intracranial atherosclerosis in a consecutive series of patients are presented.

METHODS: The demographics, procedural details, procedural outcome, and long-term neurologic follow-up in 60 consecutive patients with 71 lesions, undergoing a total of 84 procedures, were analyzed.

RESULTS: Angioplasty alone was performed in 62 procedures; 22 procedures involved stent placement. The periprocedural stroke+death rate was 4.8%. The overall complication-free success rate was 90.5%. Restenosis occurred in 23 lesions at a mean of 4.6 months; 13 were re-treated without complication. There were 4 strokes and 4 non-neurologic deaths during 224 patient-years of follow-up. The annualized stroke rate was 1.8%, and the annualized stroke+all-cause death rate was 3.0%.

CONCLUSIONS: The stroke and death rates in this consecutive series of patients with severe intracranial atherosclerotic stenosis treated with optimal endovascular therapy are considerably less than those associated with the natural history of intracranial atherosclerosis treated with maximal medical therapy. Intracranial angioplasty with conditional stent placement is technically feasible and clinically effective with a substantial reduction in long-term stroke and death." />
<meta name="DC.Contributor" content="J.C. Wojak" />
<meta name="DC.Contributor" content="D.C. Dunlap" />
<meta name="DC.Contributor" content="K.R. Hargrave" />
<meta name="DC.Contributor" content="L.A. DeAlvare" />
<meta name="DC.Contributor" content="H.S. Culbertson" />
<meta name="DC.Contributor" content="J.J. Connors" />
<meta name="article:published_time" content="2006-10-01" />
<meta name="article:section" content="INTERVENTIONAL" />
<meta name="citation_title" content="Intracranial Angioplasty and Stenting: Long-Term Results from a Single Center" />
<meta name="citation_abstract" lang="en" content="&lt;p&gt;&lt;b&gt;BACKGROUND AND PURPOSE:&lt;/b&gt; Large-vessel intracranial atherosclerotic stenosis carries a proved stroke risk of 8%–22% per year with “best medical therapy.” The long-term clinical neurologic and angiographic outcomes of angioplasty and/or stent placement for intracranial atherosclerosis in a consecutive series of patients are presented.&lt;/p&gt;&lt;p&gt;&lt;b&gt;METHODS:&lt;/b&gt; The demographics, procedural details, procedural outcome, and long-term neurologic follow-up in 60 consecutive patients with 71 lesions, undergoing a total of 84 procedures, were analyzed.&lt;/p&gt;&lt;p&gt;&lt;b&gt;RESULTS:&lt;/b&gt; Angioplasty alone was performed in 62 procedures; 22 procedures involved stent placement. The periprocedural stroke+death rate was 4.8%. The overall complication-free success rate was 90.5%. Restenosis occurred in 23 lesions at a mean of 4.6 months; 13 were re-treated without complication. There were 4 strokes and 4 non-neurologic deaths during 224 patient-years of follow-up. The annualized stroke rate was 1.8%, and the annualized stroke+all-cause death rate was 3.0%.&lt;/p&gt;&lt;p&gt;&lt;b&gt;CONCLUSIONS:&lt;/b&gt; The stroke and death rates in this consecutive series of patients with severe intracranial atherosclerotic stenosis treated with optimal endovascular therapy are considerably less than those associated with the natural history of intracranial atherosclerosis treated with maximal medical therapy. Intracranial angioplasty with conditional stent placement is technically feasible and clinically effective with a substantial reduction in long-term stroke and death.&lt;/p&gt;" />
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<meta name="twitter:title" content="Intracranial Angioplasty and Stenting: Long-Term Results from a Single Center" />
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<meta name="twitter:description" content="BACKGROUND AND PURPOSE: Large-vessel intracranial atherosclerotic stenosis carries a proved stroke risk of 8%–22% per year with “best medical therapy.” The long-term clinical neurologic and angiographic outcomes of angioplasty and/or stent placement for intracranial atherosclerosis in a consecutive series of patients are presented.

METHODS: The demographics, procedural details, procedural outcome, and long-term neurologic follow-up in 60 consecutive patients with 71 lesions, undergoing a total of 84 procedures, were analyzed.

RESULTS: Angioplasty alone was performed in 62 procedures; 22 procedures involved stent placement. The periprocedural stroke+death rate was 4.8%. The overall complication-free success rate was 90.5%. Restenosis occurred in 23 lesions at a mean of 4.6 months; 13 were re-treated without complication. There were 4 strokes and 4 non-neurologic deaths during 224 patient-years of follow-up. The annualized stroke rate was 1.8%, and the annualized stroke+all-cause death rate was 3.0%.

CONCLUSIONS: The stroke and death rates in this consecutive series of patients with severe intracranial atherosclerotic stenosis treated with optimal endovascular therapy are considerably less than those associated with the natural history of intracranial atherosclerosis treated with maximal medical therapy. Intracranial angioplasty with conditional stent placement is technically feasible and clinically effective with a substantial reduction in long-term stroke and death." />
<meta name="og-title" property="og:title" content="Intracranial Angioplasty and Stenting: Long-Term Results from a Single Center" />
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<meta name="og-description" property="og:description" content="BACKGROUND AND PURPOSE: Large-vessel intracranial atherosclerotic stenosis carries a proved stroke risk of 8%–22% per year with “best medical therapy.” The long-term clinical neurologic and angiographic outcomes of angioplasty and/or stent placement for intracranial atherosclerosis in a consecutive series of patients are presented.

METHODS: The demographics, procedural details, procedural outcome, and long-term neurologic follow-up in 60 consecutive patients with 71 lesions, undergoing a total of 84 procedures, were analyzed.

RESULTS: Angioplasty alone was performed in 62 procedures; 22 procedures involved stent placement. The periprocedural stroke+death rate was 4.8%. The overall complication-free success rate was 90.5%. Restenosis occurred in 23 lesions at a mean of 4.6 months; 13 were re-treated without complication. There were 4 strokes and 4 non-neurologic deaths during 224 patient-years of follow-up. The annualized stroke rate was 1.8%, and the annualized stroke+all-cause death rate was 3.0%.

CONCLUSIONS: The stroke and death rates in this consecutive series of patients with severe intracranial atherosclerotic stenosis treated with optimal endovascular therapy are considerably less than those associated with the natural history of intracranial atherosclerosis treated with maximal medical therapy. Intracranial angioplasty with conditional stent placement is technically feasible and clinically effective with a substantial reduction in long-term stroke and death." />
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        	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-volume highwire-cite-metadata">Vol. 27</span>, <span  class="highwire-cite-metadata-issue highwire-cite-metadata">Issue 9 </span><div  class="highwire-cite-metadata-pubdate highwire-cite-metadata">October 2006 </div></div>
      
      
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      <div class="highwire-cite-title">Intracranial Angioplasty and Stenting: Long-Term Results from a Single Center</div>  
    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0"><span class="nlm-given-names">J.C.</span> <span class="nlm-surname">Wojak</span></span>, <span class="highwire-citation-author" data-delta="1"><span class="nlm-given-names">D.C.</span> <span class="nlm-surname">Dunlap</span></span>, <span class="highwire-citation-author" data-delta="2"><span class="nlm-given-names">K.R.</span> <span class="nlm-surname">Hargrave</span></span>, <span class="highwire-citation-author" data-delta="3"><span class="nlm-given-names">L.A.</span> <span class="nlm-surname">DeAlvare</span></span>, <span class="highwire-citation-author" data-delta="4"><span class="nlm-given-names">H.S.</span> <span class="nlm-surname">Culbertson</span></span>, <span class="highwire-citation-author" data-delta="5"><span class="nlm-given-names">J.J.</span> <span class="nlm-surname">Connors</span></span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">Oct 2006, </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">27 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(9) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">1882-1892; </span></div>
  
  
  
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    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0"><span class="nlm-given-names">J.C.</span> <span class="nlm-surname">Wojak</span></span>, <span class="highwire-citation-author" data-delta="1"><span class="nlm-given-names">D.C.</span> <span class="nlm-surname">Dunlap</span></span>, <span class="highwire-citation-author" data-delta="2"><span class="nlm-given-names">K.R.</span> <span class="nlm-surname">Hargrave</span></span>, <span class="highwire-citation-author" data-delta="3"><span class="nlm-given-names">L.A.</span> <span class="nlm-surname">DeAlvare</span></span>, <span class="highwire-citation-author" data-delta="4"><span class="nlm-given-names">H.S.</span> <span class="nlm-surname">Culbertson</span></span>, <span class="highwire-citation-author" data-delta="5"><span class="nlm-given-names">J.J.</span> <span class="nlm-surname">Connors</span></span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">Oct 2006, </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">27 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(9) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">1882-1892; </span></div>
  
  
  
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