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<meta name="DC.Title" content="Posterior Reversible Encephalopathy Syndrome after Solid Organ Transplantation" />
<meta name="DC.Identifier" content="10.3174/ajnr.A0960" />
<meta name="DC.Date" content="2008-05-01" />
<meta name="DC.Publisher" content="American Journal of Neuroradiology" />
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<meta name="DC.Description" content="BACKGROUND AND PURPOSE: Posterior reversible encephalopathy syndrome (PRES) is known to occur after solid organ transplantation (SOT), potentially associated with cyclosporine and tacrolimus. In this study, we assess the frequency and clinical and imaging characteristics of PRES after SOT.

MATERIALS AND METHODS: We identified 27 patients (13 men and 14 women; age range, 22–72 years) who developed PRES after SOT. Features noted included SOT subtype, incidence and timing of PRES, infection and rejection, mean arterial pressure (MAP), and toxicity brain edema.

RESULTS: PRES developed in 21 (0.49%) of 4222 patients who underwent transplantation within the study period (no significant difference among SOT subtypes). Transplantation was performed in 5 patients before the study period, and 1 patient underwent transplantation elsewhere. In consideration of all 27 patients, PRES typically developed in the first 2 months in patients who had SOT of the liver (9 of 10 patients) and was associated with cytomegalovirus (CMV), mild rejection, or systemic bacterial infection. PRES also typically developed after 1 year in patients who had SOT of the kidney (8 of 9 patients) and was associated with moderate rejection or bacterial infection. Toxicity MAP was significantly lower ( P &lt; .001) in liver transplants (average MAP, 104.8 ± 16 mm Hg) compared with that in kidney transplants (average MAP, 143 ± 20 mm Hg). Toxicity brain edema was significantly greater ( P &lt; .001) in patients who had liver transplants and developed PRES compared with patients who had undergone kidney transplants despite severe hypertension in those who had the kidney transplants.

CONCLUSION: Patients who had undergone SOTs have a similar low incidence of developing PRES. Differences between those who have had liver and kidney transplants included time after transplant, toxicity MAP, and PRES vasogenic edema noted at presentation. In patients who have undergone kidney transplants, severely elevated MAP was associated with reduced, not greater, brain edema." />
<meta name="DC.Contributor" content="W.S. Bartynski" />
<meta name="DC.Contributor" content="H.P. Tan" />
<meta name="DC.Contributor" content="J.F. Boardman" />
<meta name="DC.Contributor" content="R. Shapiro" />
<meta name="DC.Contributor" content="J.W. Marsh" />
<meta name="article:published_time" content="2008-05-01" />
<meta name="article:section" content="BRAIN" />
<meta name="citation_title" content="Posterior Reversible Encephalopathy Syndrome after Solid Organ Transplantation" />
<meta name="citation_abstract" lang="en" content="&lt;p&gt;&lt;b&gt;BACKGROUND AND PURPOSE:&lt;/b&gt; Posterior reversible encephalopathy syndrome (PRES) is known to occur after solid organ transplantation (SOT), potentially associated with cyclosporine and tacrolimus. In this study, we assess the frequency and clinical and imaging characteristics of PRES after SOT.&lt;/p&gt;&lt;p&gt;&lt;b&gt;MATERIALS AND METHODS:&lt;/b&gt; We identified 27 patients (13 men and 14 women; age range, 22–72 years) who developed PRES after SOT. Features noted included SOT subtype, incidence and timing of PRES, infection and rejection, mean arterial pressure (MAP), and toxicity brain edema.&lt;/p&gt;&lt;p&gt;&lt;b&gt;RESULTS:&lt;/b&gt; PRES developed in 21 (0.49%) of 4222 patients who underwent transplantation within the study period (no significant difference among SOT subtypes). Transplantation was performed in 5 patients before the study period, and 1 patient underwent transplantation elsewhere. In consideration of all 27 patients, PRES typically developed in the first 2 months in patients who had SOT of the liver (9 of 10 patients) and was associated with cytomegalovirus (CMV), mild rejection, or systemic bacterial infection. PRES also typically developed after 1 year in patients who had SOT of the kidney (8 of 9 patients) and was associated with moderate rejection or bacterial infection. Toxicity MAP was significantly lower (&lt;i&gt;P&lt;/i&gt; &amp;lt; .001) in liver transplants (average MAP, 104.8 ± 16 mm Hg) compared with that in kidney transplants (average MAP, 143 ± 20 mm Hg). Toxicity brain edema was significantly greater (&lt;i&gt;P&lt;/i&gt; &amp;lt; .001) in patients who had liver transplants and developed PRES compared with patients who had undergone kidney transplants despite severe hypertension in those who had the kidney transplants.&lt;/p&gt;&lt;p&gt;&lt;b&gt;CONCLUSION:&lt;/b&gt; Patients who had undergone SOTs have a similar low incidence of developing PRES. Differences between those who have had liver and kidney transplants included time after transplant, toxicity MAP, and PRES vasogenic edema noted at presentation. In patients who have undergone kidney transplants, severely elevated MAP was associated with reduced, not greater, brain edema.&lt;/p&gt;" />
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<meta name="citation_doi" content="10.3174/ajnr.A0960" />
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<meta name="citation_reference" content="citation_title=Journal of computer assisted tomography;citation_journal_abbrev=J Comput Assist Tomogr;citation_title=Watershed imaging features and clinical vascular injury in cyclosporin A neurotoxicity.;citation_pages=872-880;citation_volume=21;citation_year=1997;citation_issue=6;citation_pmid=9386275;citation_doi=10.1097/00004728-199711000-00005" />
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<meta name="citation_reference" content="citation_title=American Journal of Neuroradiology;citation_journal_abbrev=Am. J. Neuroradiol.;citation_title=Posterior Reversible Encephalopathy Syndrome: Prognostic Utility of Quantitative Diffusion-Weighted MR Images;citation_pages=1038-1048;citation_volume=23;citation_year=2002;citation_issue=6;citation_issn=0195-6108;citation_pmid=12063238" />
<meta name="citation_reference" content="citation_title=New England Journal of Medicine;citation_journal_abbrev=NEJM;citation_title=A Reversible Posterior Leukoencephalopathy Syndrome;citation_pages=494-500;citation_volume=334;citation_year=1996;citation_issue=8;citation_issn=0028-4793;citation_pmid=8559202;citation_doi=10.1056/NEJM199602223340803" />
<meta name="citation_reference" content="citation_title=Radiology;citation_journal_abbrev=Radiology;citation_title=Reversible Posterior Leukoencephalopathy Syndrome: Evaluation with Diffusion-Tensor MR Imaging;citation_pages=756-765;citation_volume=219;citation_year=2001;citation_issue=3;citation_issn=0033-8419;citation_pmid=11376265;citation_doi=10.1148/radiology.219.3.r01jn48756" />
<meta name="citation_reference" content="citation_title=American Journal of Neuroradiology;citation_journal_abbrev=Am. J. Neuroradiol.;citation_title=Quantitative Assessment of Diffusion Abnormalities in Posterior Reversible Encephalopathy Syndrome;citation_pages=1455-1461;citation_volume=22;citation_year=2001;citation_issue=8;citation_issn=0195-6108;citation_pmid=11559490" />
<meta name="citation_reference" content="citation_title=American Journal of Neuroradiology;citation_journal_abbrev=Am. J. Neuroradiol.;citation_title=Brain MR Imaging Abnormalities in Kidney Transplant Recipients;citation_pages=2282-2289;citation_volume=26;citation_year=2005;citation_issue=9;citation_issn=0195-6108;citation_pmid=16219834" />
<meta name="citation_reference" content="citation_title=American Journal of Roentgenology;citation_journal_abbrev=Am. J. Roentgenol.;citation_title=Neuroimaging findings in patients on immunosuppressive therapy: experience with tacrolimus toxicity;citation_pages=683-688;citation_volume=166;citation_year=1996;citation_issue=3;citation_issn=0361-803X;citation_pmid=8623651" />
<meta name="citation_reference" content="citation_title=Clinical transplantation;citation_journal_abbrev=Clin Transplant;citation_title=Impairment of the blood-brain barrier can result in tacrolimus-induced reversible leucoencephalopathy following heart transplantation.;citation_pages=469-472;citation_volume=17;citation_year=2003;citation_issue=5;citation_pmid=14703933;citation_doi=10.1034/j.1399-0012.2003.00071.x" />
<meta name="citation_reference" content="citation_title=Transplantation proceedings;citation_journal_abbrev=Transplant Proc;citation_title=Cyclosporine-related neurotoxicity in a patient after bilateral lung transplantation for cystic fibrosis.;citation_pages=2837-2839;citation_volume=36;citation_year=2004;citation_issue=9;citation_pmid=15621163;citation_doi=10.1016/j.transproceed.2004.09.072" />
<meta name="citation_reference" content="citation_title=Pediatric nephrology (Berlin, Germany);citation_journal_abbrev=Pediatr Nephrol;citation_title=Reversible encephalopathy associated with tacrolimus in pediatric renal transplants.;citation_pages=537-542;citation_volume=16;citation_year=2001;citation_issue=7;citation_pmid=11465799;citation_doi=10.1007/s004670100602" />
<meta name="citation_reference" content="citation_title=The Annals of Thoracic Surgery;citation_journal_abbrev=Ann. Thorac. Surg.;citation_title=FK506-Induced Fulminant Leukoencephalopathy After Single-Lung Transplantation;citation_pages=1461-1464;citation_volume=64;citation_year=1997;citation_issue=5;citation_issn=0003-4975;citation_pmid=9386723;citation_doi=10.1016/S0003-4975(97)00939-9" />
<meta name="citation_reference" content="citation_title=Journal of computer assisted tomography;citation_journal_abbrev=J Comput Assist Tomogr;citation_title=Neuroimaging of delayed eclampsia. Report of 3 cases and review of the literature.;citation_pages=699-713;citation_volume=27;citation_year=2003;citation_issue=5;citation_pmid=14501361;citation_doi=10.1097/00004728-200309000-00007" />
<meta name="citation_reference" content="citation_title=American Journal of Neuroradiology;citation_journal_abbrev=Am. J. Neuroradiol.;citation_title=MR angiography of cerebral vasospasm in preeclampsia;citation_pages=1344-1346;citation_volume=16;citation_year=1995;citation_issue=6;citation_issn=0195-6108;citation_pmid=7677037" />
<meta name="citation_reference" content="citation_title=Stroke;citation_journal_abbrev=Stroke;citation_title=Diffusion-Weighted Imaging Discriminates Between Cytotoxic and Vasogenic Edema in a Patient With Eclampsia;citation_pages=1082-1085;citation_volume=28;citation_year=1997;citation_issue=5;citation_issn=0039-2499;citation_pmid=9158653;citation_doi=10.1161/01.STR.28.5.1082" />
<meta name="citation_reference" content="citation_title=Transplantation;citation_journal_abbrev=Transplantation;citation_title=Immunosuppressive-associated leukoencephalopathy in organ transplant recipients.;citation_pages=467-472;citation_volume=69;citation_year=2000;citation_issue=4;citation_pmid=10708096;citation_doi=10.1097/00007890-200002270-00001" />
<meta name="citation_reference" content="citation_title=American Journal of Neuroradiology;citation_journal_abbrev=Am. J. Neuroradiol.;citation_title=Posterior Reversible Encephalopathy Syndrome in Infection, Sepsis, and Shock;citation_pages=2179-2190;citation_volume=27;citation_year=2006;citation_issue=10;citation_issn=0195-6108;citation_pmid=17110690" />
<meta name="citation_reference" content="citation_title=American Journal of Roentgenology;citation_journal_abbrev=Am. J. Roentgenol.;citation_title=Cyclosporine neurotoxicity and its relationship to hypertensive encephalopathy: CT and MR findings in 16 cases;citation_pages=627-631;citation_volume=165;citation_year=1995;citation_issue=3;citation_issn=0361-803X;citation_pmid=7645483;citation_doi=10.2214/ajr.165.3.7645483" />
<meta name="citation_reference" content="citation_title=The Journal of Rheumatology;citation_journal_abbrev=The Journal of Rheumatology;citation_title=Posterior reversible encephalopathy syndrome--an underrecognized manifestation of systemic lupus erythematosus.;citation_pages=2178-2183;citation_volume=33;citation_year=2006;citation_issue=11;citation_issn=0315-162X;citation_pmid=16960925" />
<meta name="citation_reference" content="citation_title=Annals of the Rheumatic Diseases;citation_journal_abbrev=Ann Rheum Dis;citation_title=Reversible posterior leucoencephalopathy in scleroderma;citation_pages=1803-1804;citation_volume=64;citation_year=2005;citation_issue=12;citation_issn=0003-4967;citation_pmid=16284354;citation_doi=10.1136/ard.2005.038273" />
<meta name="citation_reference" content="citation_title=New England Journal of Medicine;citation_journal_abbrev=NEJM;citation_title=Reversible posterior leukoencephalopathy syndrome and bevacizumab.;citation_pages=980-982;citation_volume=354;citation_year=2006;citation_issue=9;citation_issn=0028-4793;citation_pmid=16514715;citation_doi=10.1056/NEJMc052954" />
<meta name="citation_reference" content="citation_title=American Journal of Neuroradiology;citation_journal_abbrev=Am. J. Neuroradiol.;citation_title=Cisplatin neurotoxicity presenting as reversible posterior leukoencephalopathy syndrome;citation_pages=415-417;citation_volume=19;citation_year=1998;citation_issue=3;citation_issn=0195-6108;citation_pmid=9541291" />
<meta name="citation_reference" content="citation_title=New England Journal of Medicine;citation_journal_abbrev=NEJM;citation_title=Reversible posterior leukoencephalopathy syndrome and bevacizumab.;citation_pages=980-982;citation_volume=354;citation_year=2006;citation_issue=9;citation_issn=0028-4793;citation_pmid=16514715;citation_doi=10.1056/NEJMc052954" />
<meta name="citation_reference" content="citation_title=Journal of computer assisted tomography;citation_journal_abbrev=J Comput Assist Tomogr;citation_title=Transient Ara-C leukoencephalopathy: MR findings.;citation_pages=161-162;citation_volume=20;citation_year=1996;citation_issue=1;citation_pmid=8576470" />
<meta name="citation_reference" content="citation_title=Journal of computer assisted tomography;citation_journal_abbrev=J Comput Assist Tomogr;citation_title=Reversible cerebral lesions associated with tiazofurin usage: MR demonstration.;citation_pages=1078-1081;citation_volume=12;citation_year=1988;citation_issue=6;citation_pmid=3183120" />
<meta name="citation_reference" content="citation_title=Magnetic resonance imaging;citation_journal_abbrev=Magn Reson Imaging;citation_title=Gemcitabine-associated posterior reversible encephalopathy syndrome: MR imaging and MR spectroscopy findings.;citation_pages=129-132;citation_volume=19;citation_year=2001;citation_issue=1;citation_pmid=11295355;citation_doi=10.1016/S0730-725X(01)00217-X" />
<meta name="citation_reference" content="citation_title=Journal of neurology;citation_journal_abbrev=J Neurol;citation_title=Cyclosporine neurotoxicity: a review.;citation_pages=339-346;citation_volume=246;citation_year=1999;citation_issue=5;citation_pmid=10399863;citation_doi=10.1007/s004150050360" />
<meta name="citation_reference" content="citation_title=Neurology;citation_journal_abbrev=Neurology;citation_title=Posterior leukoencephalopathy without severe hypertension: Utility of diffusion-weighted MRI;citation_pages=1369-1376;citation_volume=51;citation_year=1998;citation_issue=5;citation_issn=0028-3878;citation_pmid=9818862" />
<meta name="citation_reference" content="citation_title=American journal of obstetrics and gynecology;citation_journal_abbrev=Am J Obstet Gynecol;citation_title=Eclampsia. VI. Maternal-perinatal outcome in 254 consecutive cases.;citation_pages=1049-1054;citation_volume=163;citation_year=1990;citation_issue=3;citation_pmid=2403130;citation_doi=10.1016/0002-9378(90)91123-T" />
<meta name="citation_reference" content="citation_title=American Journal of Neuroradiology;citation_journal_abbrev=Am. J. Neuroradiol.;citation_title=Distinct Imaging Patterns and Lesion Distribution in Posterior Reversible Encephalopathy Syndrome;citation_pages=1320-1327;citation_volume=28;citation_year=2007;citation_issue=7;citation_issn=0195-6108;citation_pmid=17698535;citation_doi=10.3174/ajnr.A0549" />
<meta name="citation_reference" content="citation_title=American Journal of Neuroradiology;citation_journal_abbrev=Am. J. Neuroradiol.;citation_title=Pretransplantation Conditioning Influence on the Occurrence of Cyclosporine or FK-506 Neurotoxicity in Allogeneic Bone Marrow Transplantation;citation_pages=261-269;citation_volume=25;citation_year=2004;citation_issue=2;citation_issn=0195-6108;citation_pmid=14970028" />
<meta name="citation_reference" content="citation_title=Bone marrow transplantation;citation_journal_abbrev=Bone Marrow Transplant;citation_title=Clinical outcome after conversion to FK 506 (tacrolimus) therapy for acute graft-versus-host disease resistant to cyclosporine or for cyclosporine-associated toxicities.;citation_pages=985-991;citation_volume=26;citation_year=2000;citation_issue=9;citation_pmid=11100278;citation_doi=10.1038/sj.bmt.1702639" />
<meta name="citation_reference" content="citation_title=Transplantation;citation_journal_abbrev=Transplantation;citation_title=Conversion to neoral for neurotoxicity after primary adult liver transplantation under tacrolimus.;citation_pages=172-176;citation_volume=69;citation_year=2000;citation_issue=1;citation_pmid=10653398;citation_doi=10.1097/00007890-200001150-00029" />
<meta name="citation_reference" content="citation_title=American Journal of Neuroradiology;citation_journal_abbrev=Am. J. Neuroradiol.;citation_title=Hemodynamic and Permeability Changes in Posterior Reversible Encephalopathy Syndrome Measured by Dynamic Susceptibility Perfusion-Weighted MR Imaging;citation_pages=825-830;citation_volume=26;citation_year=2005;citation_issue=4;citation_issn=0195-6108;citation_pmid=15814928" />
<meta name="citation_reference" content="citation_title=Neuroradiology;citation_journal_abbrev=Neuroradiology;citation_title=Assessment of vasogenic edema in eclampsia using diffusion imaging.;citation_pages=818-820;citation_volume=42;citation_year=2000;citation_issue=11;citation_pmid=11151687;citation_doi=10.1007/s002340000439" />
<meta name="citation_reference" content="citation_title=British journal of obstetrics and gynaecology;citation_journal_abbrev=Br J Obstet Gynaecol;citation_title=Single photon emission and cerebral computerised tomographic scan and transcranial Doppler sonographic findings in eclampsia.;citation_pages=1165-1172;citation_volume=104;citation_year=1997;citation_issue=10;citation_pmid=9332995" />
<meta name="citation_reference" content="citation_title=American Journal of Neuroradiology;citation_journal_abbrev=Am. J. Neuroradiol.;citation_title=Prolonged Reversible Vasospasm in Cyclosporin A-Induced Encephalopathy;citation_pages=102-104;citation_volume=24;citation_year=2003;citation_issue=1;citation_issn=0195-6108;citation_pmid=12533334" />
<meta name="citation_reference" content="citation_title=Annals of neurology;citation_journal_abbrev=Ann Neurol;citation_title=Delayed peripartum vasculopathy: cerebral eclampsia revisited.;citation_pages=222-225;citation_volume=33;citation_year=1993;citation_issue=2;citation_pmid=8434886;citation_doi=10.1002/ana.410330215" />
<meta name="citation_reference" content="citation_title=Stroke;citation_journal_abbrev=Stroke;citation_title=Cerebral vasospasm and eclampsia;citation_pages=326-329;citation_volume=19;citation_year=1988;citation_issue=3;citation_issn=0039-2499;citation_pmid=3354016" />
<meta name="citation_reference" content="citation_title=Neurology;citation_journal_abbrev=Neurology;citation_title=Neurologic involvement in toxemia of pregnancy: Reversible MRI lesions;citation_pages=167-167;citation_volume=40;citation_year=1990;citation_issue=1;citation_issn=0028-3878;citation_pmid=2296368" />
<meta name="citation_reference" content="citation_title=Transplantation;citation_journal_abbrev=Transplantation;citation_title=Central nervous system lesions in liver transplant recipients: prospective assessment of indications for biopsy and implications for management.;citation_pages=1596-1604;citation_volume=66;citation_year=1998;citation_issue=12;citation_pmid=9884245;citation_doi=10.1097/00007890-199812270-00005" />
<meta name="citation_reference" content="citation_title=Archives of Disease in Childhood;citation_journal_abbrev=Arch. Dis. Child.;citation_title=Unusual cyclosporin related neurological complications in recipients of liver transplants.;citation_pages=405-407;citation_volume=68;citation_year=1993;citation_issue=3;citation_issn=0003-9888;citation_pmid=8466245;citation_doi=10.1136/adc.68.3.405" />
<meta name="citation_reference" content="citation_title=Child nephrology and urology;citation_journal_abbrev=Child Nephrol Urol;citation_title=Central nervous system complications in children treated with ciclosporin after renal transplantation.;citation_pages=225-230;citation_volume=10;citation_year=1990;citation_issue=4;citation_pmid=2088597" />
<meta name="citation_reference" content="citation_title=New England Journal of Medicine;citation_journal_abbrev=NEJM;citation_title=Central nervous system toxicity after liver transplantation. The role of cyclosporine and cholesterol;citation_pages=861-866;citation_volume=317;citation_year=1987;citation_issue=14;citation_issn=0028-4793;citation_pmid=3306386;citation_doi=10.1056/NEJM198710013171404" />
<meta name="citation_reference" content="citation_title=Transplantation proceedings;citation_journal_abbrev=Transplant Proc;citation_title=Cyclosporine neurotoxicity in liver transplant recipients: report of three cases.;citation_pages=116-118;citation_volume=20;citation_year=1988;citation_issue=1;citation_pmid=3278452" />
<meta name="citation_reference" content="citation_title=Bone marrow transplantation;citation_journal_abbrev=Bone Marrow Transplant;citation_title=Neurologic complications in allogeneic bone marrow transplant patients receiving cyclosporin.;citation_pages=393-401;citation_volume=8;citation_year=1991;citation_issue=5;citation_pmid=1768975" />
<meta name="citation_reference" content="citation_title=American Journal of Neuroradiology;citation_journal_abbrev=Am. J. Neuroradiol.;citation_title=The effect of human leukocyte antigen disparity on cyclosporine neurotoxicity after allogeneic bone marrow transplantation;citation_pages=601-608;citation_volume=19;citation_year=1998;citation_issue=4;citation_issn=0195-6108;citation_pmid=9576643" />
<meta name="citation_reference" content="citation_journal_abbrev=Neurocrit Care;citation_title=Variable incidence of cyclosporine and FK-506 neurotoxicity in hematopoeitic malignancies and marrow conditions after allogeneic bone marrow transplantation.;citation_pages=33-45;citation_volume=3;citation_year=2005;citation_issue=1;citation_pmid=16159093;citation_doi=10.1385/NCC:3:1:033" />
<meta name="citation_reference" content="citation_title=Bone Marrow Transplant.;citation_pages=94;citation_year=1996" />
<meta name="citation_reference" content="citation_title=Journal of hematotherapy &amp; stem cell research;citation_journal_abbrev=J Hematother Stem Cell Res;citation_title=Pathogenesis of acute graft-versus-host disease: cytokines and cellular effectors.;citation_pages=299-306;citation_volume=9;citation_year=2000;citation_issue=3;citation_pmid=10894351;citation_doi=10.1089/15258160050079407" />
<meta name="citation_reference" content="citation_title=Bone Marrow Transplant.;citation_pages=478;citation_year=1996" />
<meta name="citation_reference" content="citation_title=Bone Marrow Transplant.;citation_pages=438;citation_year=1996" />
<meta name="citation_reference" content="citation_title=Handbook of Kidney Transplantation;citation_pages=1;citation_year=2005" />
<meta name="citation_reference" content="citation_title=Handbook of Kidney Transplantation;citation_pages=193;citation_year=2005" />
<meta name="citation_reference" content="citation_title=Transplantation Surgery.;citation_pages=43;citation_year=2001" />
<meta name="citation_reference" content="citation_title=Organ Transplantation;citation_pages=1;citation_year=2003" />
<meta name="citation_reference" content="citation_title=Transplantation proceedings;citation_journal_abbrev=Transplant Proc;citation_title=Desensitized renal transplant recipients show reduced cellular responses to in vitro challenge.;citation_pages=3416-3417;citation_volume=38;citation_year=2006;citation_issue=10;citation_pmid=17175290;citation_doi=10.1016/j.transproceed.2006.10.155" />
<meta name="citation_reference" content="citation_title=Clinical Microbiology Reviews;citation_journal_abbrev=Clin. Microbiol. Rev.;citation_title=Bacterial pyrogenic exotoxins as superantigens;citation_pages=411-426;citation_volume=8;citation_year=1995;citation_issue=3;citation_issn=0893-8512;citation_pmid=7553574" />
<meta name="citation_reference" content="citation_title=Principles and Practice of Infectious Diseases.;citation_pages=906;citation_year=2005" />
<meta name="citation_reference" content="citation_title=Transplantation of the Liver.;citation_pages=5;citation_year=2001" />
<meta name="citation_reference" content="citation_title=Hepatology (Baltimore, Md.);citation_journal_abbrev=Hepatology;citation_title=Altered platelet function in cirrhosis of the liver: impairment of inositol lipid and arachidonic acid metabolism in response to agonists;citation_pages=1620-1626;citation_volume=8;citation_year=1988;citation_issue=6;citation_pmid=3142812;citation_doi=10.1002/hep.1840080625" />
<meta name="citation_reference" content="citation_title=American journal of hematology;citation_journal_abbrev=Am J Hematol;citation_title=Quantitative defect of glycoprotein Ib in severe cirrhotic patients.;citation_pages=10-15;citation_volume=45;citation_year=1994;citation_issue=1;citation_pmid=8250006;citation_doi=10.1002/ajh.2830450103" />
<meta name="citation_reference" content="citation_title=Transplantation Surgery.;citation_pages=181;citation_year=2001" />
<meta name="citation_reference" content="citation_title=Transplantation of the Liver;citation_pages=131;citation_year=2001" />
<meta name="citation_reference" content="citation_title=Nature; Physical Science (London);citation_journal_abbrev=Nature; Physical Science (London);citation_title=Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin.;citation_pages=458-462;citation_volume=405;citation_year=2000;citation_issue=6785;citation_pmid=10839541;citation_doi=10.1038/35013070" />
<meta name="citation_reference" content="citation_title=Clin Infect Dis;citation_pages=S162;citation_volume=31 Suppl 5;citation_year=2000" />
<meta name="citation_reference" content="citation_title=Transplantation of the Liver.;citation_pages=274;citation_year=1996" />
<meta name="twitter:title" content="Posterior Reversible Encephalopathy Syndrome after Solid Organ Transplantation" />
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<meta name="twitter:description" content="BACKGROUND AND PURPOSE: Posterior reversible encephalopathy syndrome (PRES) is known to occur after solid organ transplantation (SOT), potentially associated with cyclosporine and tacrolimus. In this study, we assess the frequency and clinical and imaging characteristics of PRES after SOT.

MATERIALS AND METHODS: We identified 27 patients (13 men and 14 women; age range, 22–72 years) who developed PRES after SOT. Features noted included SOT subtype, incidence and timing of PRES, infection and rejection, mean arterial pressure (MAP), and toxicity brain edema.

RESULTS: PRES developed in 21 (0.49%) of 4222 patients who underwent transplantation within the study period (no significant difference among SOT subtypes). Transplantation was performed in 5 patients before the study period, and 1 patient underwent transplantation elsewhere. In consideration of all 27 patients, PRES typically developed in the first 2 months in patients who had SOT of the liver (9 of 10 patients) and was associated with cytomegalovirus (CMV), mild rejection, or systemic bacterial infection. PRES also typically developed after 1 year in patients who had SOT of the kidney (8 of 9 patients) and was associated with moderate rejection or bacterial infection. Toxicity MAP was significantly lower ( P &lt; .001) in liver transplants (average MAP, 104.8 ± 16 mm Hg) compared with that in kidney transplants (average MAP, 143 ± 20 mm Hg). Toxicity brain edema was significantly greater ( P &lt; .001) in patients who had liver transplants and developed PRES compared with patients who had undergone kidney transplants despite severe hypertension in those who had the kidney transplants.

CONCLUSION: Patients who had undergone SOTs have a similar low incidence of developing PRES. Differences between those who have had liver and kidney transplants included time after transplant, toxicity MAP, and PRES vasogenic edema noted at presentation. In patients who have undergone kidney transplants, severely elevated MAP was associated with reduced, not greater, brain edema." />
<meta name="og-title" property="og:title" content="Posterior Reversible Encephalopathy Syndrome after Solid Organ Transplantation" />
<meta name="og-url" property="og:url" content="http://ajnr-stage2.stage.highwire.org/content/29/5/924" />
<meta name="og-site-name" property="og:site_name" content="American Journal of Neuroradiology" />
<meta name="og-description" property="og:description" content="BACKGROUND AND PURPOSE: Posterior reversible encephalopathy syndrome (PRES) is known to occur after solid organ transplantation (SOT), potentially associated with cyclosporine and tacrolimus. In this study, we assess the frequency and clinical and imaging characteristics of PRES after SOT.

MATERIALS AND METHODS: We identified 27 patients (13 men and 14 women; age range, 22–72 years) who developed PRES after SOT. Features noted included SOT subtype, incidence and timing of PRES, infection and rejection, mean arterial pressure (MAP), and toxicity brain edema.

RESULTS: PRES developed in 21 (0.49%) of 4222 patients who underwent transplantation within the study period (no significant difference among SOT subtypes). Transplantation was performed in 5 patients before the study period, and 1 patient underwent transplantation elsewhere. In consideration of all 27 patients, PRES typically developed in the first 2 months in patients who had SOT of the liver (9 of 10 patients) and was associated with cytomegalovirus (CMV), mild rejection, or systemic bacterial infection. PRES also typically developed after 1 year in patients who had SOT of the kidney (8 of 9 patients) and was associated with moderate rejection or bacterial infection. Toxicity MAP was significantly lower ( P &lt; .001) in liver transplants (average MAP, 104.8 ± 16 mm Hg) compared with that in kidney transplants (average MAP, 143 ± 20 mm Hg). Toxicity brain edema was significantly greater ( P &lt; .001) in patients who had liver transplants and developed PRES compared with patients who had undergone kidney transplants despite severe hypertension in those who had the kidney transplants.

CONCLUSION: Patients who had undergone SOTs have a similar low incidence of developing PRES. Differences between those who have had liver and kidney transplants included time after transplant, toxicity MAP, and PRES vasogenic edema noted at presentation. In patients who have undergone kidney transplants, severely elevated MAP was associated with reduced, not greater, brain edema." />
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      <h1 class="highwire-cite-title" id="page-title">Posterior Reversible Encephalopathy Syndrome after Solid Organ Transplantation</h1>  
    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0">W.S. Bartynski</span>, <span class="highwire-citation-author" data-delta="1">H.P. Tan</span>, <span class="highwire-citation-author" data-delta="2">J.F. Boardman</span>, <span class="highwire-citation-author" data-delta="3">R. Shapiro</span> and <span class="highwire-citation-author" data-delta="4">J.W. Marsh</span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">May 2008,  </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">29 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(5) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">924-930; </span><span  class="highwire-cite-metadata-doi highwire-cite-metadata">DOI: https://doi.org/10.3174/ajnr.A0960 </span></div>
  
  
  
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        	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-volume highwire-cite-metadata">Vol. 29</span>, <span  class="highwire-cite-metadata-issue highwire-cite-metadata">Issue 5 </span><div  class="highwire-cite-metadata-pubdate highwire-cite-metadata">May 2008 </div></div>
      
      
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      <div class="highwire-cite-title">Posterior Reversible Encephalopathy Syndrome after Solid Organ Transplantation</div>  
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      <div class="highwire-cite-title">Posterior Reversible Encephalopathy Syndrome after Solid Organ Transplantation</div>  
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