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<p id="p-1"><strong>SUMMARY:</strong> Bevacizumab is a humanized monoclonal antibody that was the first FDA approved therapy designed to inhibit angiogenesis. This paper will review the mechanism of action and clinical role of this antiangiogenic agent.</p>
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</div><div class="section glossary" id="glossary-1"><h2>Abbreviations</h2><dl id="def-list-1"><dt id="def-item-1">FDA<span class="def-item-dt-sep"></span></dt><dd>U.S. Food and Drug Administration<span class="def-item-dd-sep"></span></dd><dt id="def-item-2">VEGF<span class="def-item-dt-sep"></span></dt><dd>vascular endothelial growth factor</dd></dl></div><ul class="copyright-statement"><li class="fn" id="copyright-statement-1">Copyright © American Society of Neuroradiology</li></ul><span class="highwire-journal-article-marker-end"></span></div><span class="related-urls"></span></div><a href="http://ajnr-stage2.stage.highwire.org/content/31/2/235.full" class="hw-link hw-link-article-full-text" data-icon-position="" data-hide-link-title="0">View Full Text</a></div>  </div>

  
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