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<meta name="DC.Title" content="Effect of Tube Voltage on Image Quality in 64-Section Multidetector 3D CT Angiography: Evaluation with a Vascular Phantom with Superimposed Bone Skull Structures" />
<meta name="DC.Identifier" content="10.3174/ajnr.A1871" />
<meta name="DC.Date" content="2010-04-01" />
<meta name="DC.Publisher" content="American Journal of Neuroradiology" />
<meta name="DC.Rights" content="Copyright © American Society of Neuroradiology" />
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<meta name="DC.Description" content="BACKGROUND AND PURPOSE: Optimal tube voltage and tube current settings are not well established. The purpose of our study was to investigate the image quality on 3D CT angiograms of the brain at various kilovoltage settings by evaluating the depiction of simulated intracranial lesions by using a vascular phantom.

MATERIALS AND METHODS: An anthropomorphic vascular phantom with superimposed bone skull structures was designed to simulate various intracranial aneurysms with aneurysmal blebs. We performed CT angiography by using a 64-detector row CT scanner for various effective tube currents with 4 tube voltages of 80, 100, 120, and 135 kV(p). Simulated aneurysm enhancement and image noise were quantified; SNR and CNR were calculated. The depiction of the simulated aneurysms and blebs on 3D CT angiograms obtained with the volume-rendering technique was subjectively assessed. The effective dose was calculated on the basis of a CTDIw. The results of several protocols were compared by using the Student t test.

RESULTS: At identical doses levels (CTDIw), the mean SNR and CNR at 100 kV(p) were significantly higher than those at 80, 120, and 135 kV(p); and the mean qualitative image score at 100 kV(p) was significantly superior to those at 80 and 135 kV(p).

CONCLUSIONS: Our phantom study suggests that the tube voltage of 100 kV(p) is desirable for cerebral 3D CT angiograms, and the higher or lower kilovoltage settings may result in the degradation in diagnostic image quality.

CNR
:   contrast-to-noise ratio
CTDIw
:   weighted CT dose index
kV(p)
:   kilovolt (peak)
MDCT
:   multidetector row CT
ROI
:   region of interest
SNR
:   signal-to-noise ratio" />
<meta name="DC.Contributor" content="Y. Murakami" />
<meta name="DC.Contributor" content="S. Kakeda" />
<meta name="DC.Contributor" content="K. Kamada" />
<meta name="DC.Contributor" content="N. Ohnari" />
<meta name="DC.Contributor" content="J. Nishimura" />
<meta name="DC.Contributor" content="M. Ogawa" />
<meta name="DC.Contributor" content="K. Otsubo" />
<meta name="DC.Contributor" content="Y. Morishita" />
<meta name="DC.Contributor" content="Y. Korogi" />
<meta name="article:published_time" content="2010-04-01" />
<meta name="article:section" content="Patient Safety" />
<meta name="citation_title" content="Effect of Tube Voltage on Image Quality in 64-Section Multidetector 3D CT Angiography: Evaluation with a Vascular Phantom with Superimposed Bone Skull Structures" />
<meta name="citation_abstract" lang="en" content="&lt;h3&gt;BACKGROUND AND PURPOSE:&lt;/h3&gt;
&lt;p&gt;Optimal tube voltage and tube current settings are not well established. The purpose of our study was to investigate the image quality on 3D CT angiograms of the brain at various kilovoltage settings by evaluating the depiction of simulated intracranial lesions by using a vascular phantom.&lt;/p&gt;&lt;h3&gt;MATERIALS AND METHODS:&lt;/h3&gt;
&lt;p&gt;An anthropomorphic vascular phantom with superimposed bone skull structures was designed to simulate various intracranial aneurysms with aneurysmal blebs. We performed CT angiography by using a 64-detector row CT scanner for various effective tube currents with 4 tube voltages of 80, 100, 120, and 135 kV(p). Simulated aneurysm enhancement and image noise were quantified; SNR and CNR were calculated. The depiction of the simulated aneurysms and blebs on 3D CT angiograms obtained with the volume-rendering technique was subjectively assessed. The effective dose was calculated on the basis of a CTDIw. The results of several protocols were compared by using the Student &lt;i&gt;t&lt;/i&gt; test.&lt;/p&gt;&lt;h3&gt;RESULTS:&lt;/h3&gt;
&lt;p&gt;At identical doses levels (CTDIw), the mean SNR and CNR at 100 kV(p) were significantly higher than those at 80, 120, and 135 kV(p); and the mean qualitative image score at 100 kV(p) was significantly superior to those at 80 and 135 kV(p).&lt;/p&gt;&lt;h3&gt;CONCLUSIONS:&lt;/h3&gt;
&lt;p&gt;Our phantom study suggests that the tube voltage of 100 kV(p) is desirable for cerebral 3D CT angiograms, and the higher or lower kilovoltage settings may result in the degradation in diagnostic image quality.&lt;/p&gt;" />
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<meta name="twitter:title" content="Effect of Tube Voltage on Image Quality in 64-Section Multidetector 3D CT Angiography: Evaluation with a Vascular Phantom with Superimposed Bone Skull Structures" />
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<meta name="twitter:image" content="http://ajnr-stage2.stage.highwire.org/sites/default/files/highwire/ajnr/31/4.cover.gif" />
<meta name="twitter:description" content="BACKGROUND AND PURPOSE: Optimal tube voltage and tube current settings are not well established. The purpose of our study was to investigate the image quality on 3D CT angiograms of the brain at various kilovoltage settings by evaluating the depiction of simulated intracranial lesions by using a vascular phantom.

MATERIALS AND METHODS: An anthropomorphic vascular phantom with superimposed bone skull structures was designed to simulate various intracranial aneurysms with aneurysmal blebs. We performed CT angiography by using a 64-detector row CT scanner for various effective tube currents with 4 tube voltages of 80, 100, 120, and 135 kV(p). Simulated aneurysm enhancement and image noise were quantified; SNR and CNR were calculated. The depiction of the simulated aneurysms and blebs on 3D CT angiograms obtained with the volume-rendering technique was subjectively assessed. The effective dose was calculated on the basis of a CTDIw. The results of several protocols were compared by using the Student t test.

RESULTS: At identical doses levels (CTDIw), the mean SNR and CNR at 100 kV(p) were significantly higher than those at 80, 120, and 135 kV(p); and the mean qualitative image score at 100 kV(p) was significantly superior to those at 80 and 135 kV(p).

CONCLUSIONS: Our phantom study suggests that the tube voltage of 100 kV(p) is desirable for cerebral 3D CT angiograms, and the higher or lower kilovoltage settings may result in the degradation in diagnostic image quality.

CNR
:   contrast-to-noise ratio
CTDIw
:   weighted CT dose index
kV(p)
:   kilovolt (peak)
MDCT
:   multidetector row CT
ROI
:   region of interest
SNR
:   signal-to-noise ratio" />
<meta name="og-title" property="og:title" content="Effect of Tube Voltage on Image Quality in 64-Section Multidetector 3D CT Angiography: Evaluation with a Vascular Phantom with Superimposed Bone Skull Structures" />
<meta name="og-url" property="og:url" content="http://ajnr-stage2.stage.highwire.org/content/31/4/620" />
<meta name="og-site-name" property="og:site_name" content="American Journal of Neuroradiology" />
<meta name="og-description" property="og:description" content="BACKGROUND AND PURPOSE: Optimal tube voltage and tube current settings are not well established. The purpose of our study was to investigate the image quality on 3D CT angiograms of the brain at various kilovoltage settings by evaluating the depiction of simulated intracranial lesions by using a vascular phantom.

MATERIALS AND METHODS: An anthropomorphic vascular phantom with superimposed bone skull structures was designed to simulate various intracranial aneurysms with aneurysmal blebs. We performed CT angiography by using a 64-detector row CT scanner for various effective tube currents with 4 tube voltages of 80, 100, 120, and 135 kV(p). Simulated aneurysm enhancement and image noise were quantified; SNR and CNR were calculated. The depiction of the simulated aneurysms and blebs on 3D CT angiograms obtained with the volume-rendering technique was subjectively assessed. The effective dose was calculated on the basis of a CTDIw. The results of several protocols were compared by using the Student t test.

RESULTS: At identical doses levels (CTDIw), the mean SNR and CNR at 100 kV(p) were significantly higher than those at 80, 120, and 135 kV(p); and the mean qualitative image score at 100 kV(p) was significantly superior to those at 80 and 135 kV(p).

CONCLUSIONS: Our phantom study suggests that the tube voltage of 100 kV(p) is desirable for cerebral 3D CT angiograms, and the higher or lower kilovoltage settings may result in the degradation in diagnostic image quality.

CNR
:   contrast-to-noise ratio
CTDIw
:   weighted CT dose index
kV(p)
:   kilovolt (peak)
MDCT
:   multidetector row CT
ROI
:   region of interest
SNR
:   signal-to-noise ratio" />
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      <h1 class="highwire-cite-title" id="page-title">Effect of Tube Voltage on Image Quality in 64-Section Multidetector 3D CT Angiography: Evaluation with a Vascular Phantom with Superimposed Bone Skull Structures</h1>  
    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0">Y. Murakami</span>, <span class="highwire-citation-author" data-delta="1">S. Kakeda</span>, <span class="highwire-citation-author" data-delta="2">K. Kamada</span>, <span class="highwire-citation-author" data-delta="3">N. Ohnari</span>, <span class="highwire-citation-author" data-delta="4">J. Nishimura</span>, <span class="highwire-citation-author" data-delta="5">M. Ogawa</span>, <span class="highwire-citation-author" data-delta="6">K. Otsubo</span>, <span class="highwire-citation-author" data-delta="7">Y. Morishita</span> and <span class="highwire-citation-author" data-delta="8">Y. Korogi</span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">April 2010,  </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">31 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(4) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">620-625; </span><span  class="highwire-cite-metadata-doi highwire-cite-metadata">DOI: https://doi.org/10.3174/ajnr.A1871 </span></div>
  
  
  
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<div id="hw-article-author-popups-top-node-9627--6646581652" style="display: none;"><div class="author-tooltip-0"><div class="author-tooltip-name">Y. Murakami </div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=Y.%2BMurakami%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Murakami%20Y&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AY.%2BMurakami%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-1"><div class="author-tooltip-name">S. 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<p id="p-1"><strong>BACKGROUND AND PURPOSE:</strong> Optimal tube voltage and tube current settings are not well established. The purpose of our study was to investigate the image quality on 3D CT angiograms of the brain at various kilovoltage settings by evaluating the depiction of simulated intracranial lesions by using a vascular phantom.</p>
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<p id="p-2"><strong>MATERIALS AND METHODS:</strong> An anthropomorphic vascular phantom with superimposed bone skull structures was designed to simulate various intracranial aneurysms with aneurysmal blebs. We performed CT angiography by using a 64-detector row CT scanner for various effective tube currents with 4 tube voltages of 80, 100, 120, and 135 kV(p). Simulated aneurysm enhancement and image noise were quantified; SNR and CNR were calculated. The depiction of the simulated aneurysms and blebs on 3D CT angiograms obtained with the volume-rendering technique was subjectively assessed. The effective dose was calculated on the basis of a CTDIw. The results of several protocols were compared by using the Student <em>t</em> test.</p>
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<p id="p-3"><strong>RESULTS:</strong> At identical doses levels (CTDIw), the mean SNR and CNR at 100 kV(p) were significantly higher than those at 80, 120, and 135 kV(p); and the mean qualitative image score at 100 kV(p) was significantly superior to those at 80 and 135 kV(p).</p>
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<p id="p-4"><strong>CONCLUSIONS:</strong> Our phantom study suggests that the tube voltage of 100 kV(p) is desirable for cerebral 3D CT angiograms, and the higher or lower kilovoltage settings may result in the degradation in diagnostic image quality.</p>
</div></div><div class="section glossary" id="glossary-1"><h2>Abbreviations</h2><dl id="def-list-1"><dt id="def-item-1">CNR<span class="def-item-dt-sep"></span></dt><dd>contrast-to-noise ratio<span class="def-item-dd-sep"></span></dd><dt id="def-item-2">CTDIw<span class="def-item-dt-sep"></span></dt><dd>weighted CT dose index<span class="def-item-dd-sep"></span></dd><dt id="def-item-3">kV(p)<span class="def-item-dt-sep"></span></dt><dd>kilovolt (peak)<span class="def-item-dd-sep"></span></dd><dt id="def-item-4">MDCT<span class="def-item-dt-sep"></span></dt><dd>multidetector row CT<span class="def-item-dd-sep"></span></dd><dt id="def-item-5">ROI<span class="def-item-dt-sep"></span></dt><dd>region of interest<span class="def-item-dd-sep"></span></dd><dt id="def-item-6">SNR<span class="def-item-dt-sep"></span></dt><dd>signal-to-noise ratio</dd></dl></div><ul class="copyright-statement"><li class="fn" id="copyright-statement-1">Copyright © American Society of Neuroradiology</li></ul><span class="highwire-journal-article-marker-end"></span></div><span class="related-urls"></span></div><a href="http://ajnr-stage2.stage.highwire.org/content/31/4/620.full" class="hw-link hw-link-article-full-text" data-icon-position="" data-hide-link-title="0">View Full Text</a></div>  </div>

  
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        	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-volume highwire-cite-metadata">Vol. 31</span>, <span  class="highwire-cite-metadata-issue highwire-cite-metadata">Issue 4 </span><div  class="highwire-cite-metadata-pubdate highwire-cite-metadata">1 Apr 2010 </div></div>
      
      
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      <div class="highwire-cite-title">Effect of Tube Voltage on Image Quality in 64-Section Multidetector 3D CT Angiography: Evaluation with a Vascular Phantom with Superimposed Bone Skull Structures</div>  
    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0"><span class="nlm-given-names">Y.</span> <span class="nlm-surname">Murakami</span></span>, <span class="highwire-citation-author" data-delta="1"><span class="nlm-given-names">S.</span> <span class="nlm-surname">Kakeda</span></span>, <span class="highwire-citation-author" data-delta="2"><span class="nlm-given-names">K.</span> <span class="nlm-surname">Kamada</span></span>, <span class="highwire-citation-author" data-delta="3"><span class="nlm-given-names">N.</span> <span class="nlm-surname">Ohnari</span></span>, <span class="highwire-citation-author" data-delta="4"><span class="nlm-given-names">J.</span> <span class="nlm-surname">Nishimura</span></span>, <span class="highwire-citation-author" data-delta="5"><span class="nlm-given-names">M.</span> <span class="nlm-surname">Ogawa</span></span>, <span class="highwire-citation-author" data-delta="6"><span class="nlm-given-names">K.</span> <span class="nlm-surname">Otsubo</span></span>, <span class="highwire-citation-author" data-delta="7"><span class="nlm-given-names">Y.</span> <span class="nlm-surname">Morishita</span></span>, <span class="highwire-citation-author" data-delta="8"><span class="nlm-given-names">Y.</span> <span class="nlm-surname">Korogi</span></span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">Apr 2010, </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">31 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(4) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">620-625; </span><span  class="highwire-cite-metadata-doi highwire-cite-metadata"><span class="label">DOI:</span> 10.3174/ajnr.A1871 </span></div>
  
  
  
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      <div class="highwire-cite-title">Effect of Tube Voltage on Image Quality in 64-Section Multidetector 3D CT Angiography: Evaluation with a Vascular Phantom with Superimposed Bone Skull Structures</div>  
    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0"><span class="nlm-given-names">Y.</span> <span class="nlm-surname">Murakami</span></span>, <span class="highwire-citation-author" data-delta="1"><span class="nlm-given-names">S.</span> <span class="nlm-surname">Kakeda</span></span>, <span class="highwire-citation-author" data-delta="2"><span class="nlm-given-names">K.</span> <span class="nlm-surname">Kamada</span></span>, <span class="highwire-citation-author" data-delta="3"><span class="nlm-given-names">N.</span> <span class="nlm-surname">Ohnari</span></span>, <span class="highwire-citation-author" data-delta="4"><span class="nlm-given-names">J.</span> <span class="nlm-surname">Nishimura</span></span>, <span class="highwire-citation-author" data-delta="5"><span class="nlm-given-names">M.</span> <span class="nlm-surname">Ogawa</span></span>, <span class="highwire-citation-author" data-delta="6"><span class="nlm-given-names">K.</span> <span class="nlm-surname">Otsubo</span></span>, <span class="highwire-citation-author" data-delta="7"><span class="nlm-given-names">Y.</span> <span class="nlm-surname">Morishita</span></span>, <span class="highwire-citation-author" data-delta="8"><span class="nlm-given-names">Y.</span> <span class="nlm-surname">Korogi</span></span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">Apr 2010, </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">31 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(4) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">620-625; </span><span  class="highwire-cite-metadata-doi highwire-cite-metadata"><span class="label">DOI:</span> 10.3174/ajnr.A1871 </span></div>
  
  
  
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