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<meta name="DC.Title" content="Dose Exposure of Patients Undergoing Comprehensive Stroke Imaging by Multidetector-Row CT: Comparison of 320-Detector Row and 64-Detector Row CT Scanners" />
<meta name="DC.Identifier" content="10.3174/ajnr.A1971" />
<meta name="DC.Date" content="2010-06-01" />
<meta name="DC.Publisher" content="American Journal of Neuroradiology" />
<meta name="DC.Rights" content="Copyright © American Society of Neuroradiology" />
<meta name="DC.AccessRights" content="restricted" />
<meta name="DC.Description" content="BACKGROUND AND PURPOSE: Recently introduced 320-detector row CT enables whole brain perfusion imaging compared to a limited scanning area in 64-detector row CT. Our aim was to evaluate patient radiation exposure in comprehensive stroke imaging by using multidetector row CT consisting of standard CT of the head, CTA of cerebral and cervical vessels, and CTP.

MATERIAL AND METHODS: Organ doses were measured by using LiF-TLDs located at several organ sites in an Alderson-Rando phantom. Effective doses were derived from these measurements. Stroke protocols including noncontrast head CT, CTA of cerebral and cervical vessels, and CTP were performed on 320- and 64-detector row scanners.

RESULTS: Measured effective doses for the different scanning protocols ranged between 1.61 and 4.56 mSv, resulting in an effective dose for complete stroke imaging of 7.52/7.54 mSv (m/f) for 64-detector row CT and 10.56/10.6 mSv (m/f) for 320-detector row CT. The highest organ doses within the area of the primary beam were measured in the skin (92 mGy) and cerebral hemispheres (69.91 mGy). Use of an eye-protection device resulted in a 54% decrease of the lens dose measured for the combo protocol for whole-brain perfusion with the 320-detector row CT scanner.

CONCLUSIONS: Phantom measurements indicate that comprehensive stroke imaging with multidetector row CT may result in effective radiation doses from 7.52 mSv (64-detector row CT) to 10.6 mSv (320-detector row CT). The technique of 320-detector row CT offers additional information on the time course of vascular enhancement and whole-brain perfusion. Physicians should weigh the potential of the new technique against the higher radiation dose that is needed. Critical doses that would cause organ damage were not reached.

CCT
:   cerebral CT
CTA
:   CT angiography
CTDI
:   CT Dose Index
CTP
:   CT perfusion
ICA
:   internal carotid artery
ICRP
:   International Commission on Radiological Protection
LiF
:   lithium-fluoride
mAseff
:   effective milliampere-second
m/f
:   male/female
PMMA
:   polymethylmethacrylate
TLD
:   thermoluminescent dosimeter
W (T)
:   weighting factor" />
<meta name="DC.Contributor" content="S. Diekmann" />
<meta name="DC.Contributor" content="E. Siebert" />
<meta name="DC.Contributor" content="R. Juran" />
<meta name="DC.Contributor" content="M. Roll" />
<meta name="DC.Contributor" content="W. Deeg" />
<meta name="DC.Contributor" content="H.-C. Bauknecht" />
<meta name="DC.Contributor" content="F. Diekmann" />
<meta name="DC.Contributor" content="R. Klingebiel" />
<meta name="DC.Contributor" content="G. Bohner" />
<meta name="article:published_time" content="2010-06-01" />
<meta name="article:section" content="Patient Safety" />
<meta name="citation_title" content="Dose Exposure of Patients Undergoing Comprehensive Stroke Imaging by Multidetector-Row CT: Comparison of 320-Detector Row and 64-Detector Row CT Scanners" />
<meta name="citation_abstract" lang="en" content="&lt;h3&gt;BACKGROUND AND PURPOSE:&lt;/h3&gt;
&lt;p&gt;Recently introduced 320-detector row CT enables whole brain perfusion imaging compared to a limited scanning area in 64-detector row CT. Our aim was to evaluate patient radiation exposure in comprehensive stroke imaging by using multidetector row CT consisting of standard CT of the head, CTA of cerebral and cervical vessels, and CTP.&lt;/p&gt;&lt;h3&gt;MATERIAL AND METHODS:&lt;/h3&gt;
&lt;p&gt;Organ doses were measured by using LiF-TLDs located at several organ sites in an Alderson-Rando phantom. Effective doses were derived from these measurements. Stroke protocols including noncontrast head CT, CTA of cerebral and cervical vessels, and CTP were performed on 320- and 64-detector row scanners.&lt;/p&gt;&lt;h3&gt;RESULTS:&lt;/h3&gt;
&lt;p&gt;Measured effective doses for the different scanning protocols ranged between 1.61 and 4.56 mSv, resulting in an effective dose for complete stroke imaging of 7.52/7.54 mSv (m/f) for 64-detector row CT and 10.56/10.6 mSv (m/f) for 320-detector row CT. The highest organ doses within the area of the primary beam were measured in the skin (92 mGy) and cerebral hemispheres (69.91 mGy). Use of an eye-protection device resulted in a 54% decrease of the lens dose measured for the combo protocol for whole-brain perfusion with the 320-detector row CT scanner.&lt;/p&gt;&lt;h3&gt;CONCLUSIONS:&lt;/h3&gt;
&lt;p&gt;Phantom measurements indicate that comprehensive stroke imaging with multidetector row CT may result in effective radiation doses from 7.52 mSv (64-detector row CT) to 10.6 mSv (320-detector row CT). The technique of 320-detector row CT offers additional information on the time course of vascular enhancement and whole-brain perfusion. Physicians should weigh the potential of the new technique against the higher radiation dose that is needed. Critical doses that would cause organ damage were not reached.&lt;/p&gt;" />
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<meta name="twitter:title" content="Dose Exposure of Patients Undergoing Comprehensive Stroke Imaging by Multidetector-Row CT: Comparison of 320-Detector Row and 64-Detector Row CT Scanners" />
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<meta name="twitter:description" content="BACKGROUND AND PURPOSE: Recently introduced 320-detector row CT enables whole brain perfusion imaging compared to a limited scanning area in 64-detector row CT. Our aim was to evaluate patient radiation exposure in comprehensive stroke imaging by using multidetector row CT consisting of standard CT of the head, CTA of cerebral and cervical vessels, and CTP.

MATERIAL AND METHODS: Organ doses were measured by using LiF-TLDs located at several organ sites in an Alderson-Rando phantom. Effective doses were derived from these measurements. Stroke protocols including noncontrast head CT, CTA of cerebral and cervical vessels, and CTP were performed on 320- and 64-detector row scanners.

RESULTS: Measured effective doses for the different scanning protocols ranged between 1.61 and 4.56 mSv, resulting in an effective dose for complete stroke imaging of 7.52/7.54 mSv (m/f) for 64-detector row CT and 10.56/10.6 mSv (m/f) for 320-detector row CT. The highest organ doses within the area of the primary beam were measured in the skin (92 mGy) and cerebral hemispheres (69.91 mGy). Use of an eye-protection device resulted in a 54% decrease of the lens dose measured for the combo protocol for whole-brain perfusion with the 320-detector row CT scanner.

CONCLUSIONS: Phantom measurements indicate that comprehensive stroke imaging with multidetector row CT may result in effective radiation doses from 7.52 mSv (64-detector row CT) to 10.6 mSv (320-detector row CT). The technique of 320-detector row CT offers additional information on the time course of vascular enhancement and whole-brain perfusion. Physicians should weigh the potential of the new technique against the higher radiation dose that is needed. Critical doses that would cause organ damage were not reached.

CCT
:   cerebral CT
CTA
:   CT angiography
CTDI
:   CT Dose Index
CTP
:   CT perfusion
ICA
:   internal carotid artery
ICRP
:   International Commission on Radiological Protection
LiF
:   lithium-fluoride
mAseff
:   effective milliampere-second
m/f
:   male/female
PMMA
:   polymethylmethacrylate
TLD
:   thermoluminescent dosimeter
W (T)
:   weighting factor" />
<meta name="og-title" property="og:title" content="Dose Exposure of Patients Undergoing Comprehensive Stroke Imaging by Multidetector-Row CT: Comparison of 320-Detector Row and 64-Detector Row CT Scanners" />
<meta name="og-url" property="og:url" content="http://ajnr-stage2.stage.highwire.org/content/31/6/1003" />
<meta name="og-site-name" property="og:site_name" content="American Journal of Neuroradiology" />
<meta name="og-description" property="og:description" content="BACKGROUND AND PURPOSE: Recently introduced 320-detector row CT enables whole brain perfusion imaging compared to a limited scanning area in 64-detector row CT. Our aim was to evaluate patient radiation exposure in comprehensive stroke imaging by using multidetector row CT consisting of standard CT of the head, CTA of cerebral and cervical vessels, and CTP.

MATERIAL AND METHODS: Organ doses were measured by using LiF-TLDs located at several organ sites in an Alderson-Rando phantom. Effective doses were derived from these measurements. Stroke protocols including noncontrast head CT, CTA of cerebral and cervical vessels, and CTP were performed on 320- and 64-detector row scanners.

RESULTS: Measured effective doses for the different scanning protocols ranged between 1.61 and 4.56 mSv, resulting in an effective dose for complete stroke imaging of 7.52/7.54 mSv (m/f) for 64-detector row CT and 10.56/10.6 mSv (m/f) for 320-detector row CT. The highest organ doses within the area of the primary beam were measured in the skin (92 mGy) and cerebral hemispheres (69.91 mGy). Use of an eye-protection device resulted in a 54% decrease of the lens dose measured for the combo protocol for whole-brain perfusion with the 320-detector row CT scanner.

CONCLUSIONS: Phantom measurements indicate that comprehensive stroke imaging with multidetector row CT may result in effective radiation doses from 7.52 mSv (64-detector row CT) to 10.6 mSv (320-detector row CT). The technique of 320-detector row CT offers additional information on the time course of vascular enhancement and whole-brain perfusion. Physicians should weigh the potential of the new technique against the higher radiation dose that is needed. Critical doses that would cause organ damage were not reached.

CCT
:   cerebral CT
CTA
:   CT angiography
CTDI
:   CT Dose Index
CTP
:   CT perfusion
ICA
:   internal carotid artery
ICRP
:   International Commission on Radiological Protection
LiF
:   lithium-fluoride
mAseff
:   effective milliampere-second
m/f
:   male/female
PMMA
:   polymethylmethacrylate
TLD
:   thermoluminescent dosimeter
W (T)
:   weighting factor" />
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      <div class="highwire-cite-overline"><span  class="highwire-cite-metadata-article-type highwire-cite-metadata">Research Article</span><span class="separator-pipe"></span><span  class="highwire-cite-metadata-art-cat highwire-cite-metadata"><span class="wrapper">Patient Safety</span></span><span class="separator-pipe"></span><span  class="highwire-cite-metadata-art-series highwire-cite-metadata">F</span></div>
  
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      <h1 class="highwire-cite-title" id="page-title">Dose Exposure of Patients Undergoing Comprehensive Stroke Imaging by Multidetector-Row CT: Comparison of 320-Detector Row and 64-Detector Row CT Scanners</h1>  
    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0">S. Diekmann</span>, <span class="highwire-citation-author" data-delta="1">E. Siebert</span>, <span class="highwire-citation-author" data-delta="2">R. Juran</span>, <span class="highwire-citation-author" data-delta="3">M. Roll</span>, <span class="highwire-citation-author" data-delta="4">W. Deeg</span>, <span class="highwire-citation-author" data-delta="5">H.-C. Bauknecht</span>, <span class="highwire-citation-author" data-delta="6">F. Diekmann</span>, <span class="highwire-citation-author" data-delta="7">R. Klingebiel</span> and <span class="highwire-citation-author" data-delta="8">G. Bohner</span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">June 2010,  </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">31 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(6) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">1003-1009; </span><span  class="highwire-cite-metadata-doi highwire-cite-metadata">DOI: https://doi.org/10.3174/ajnr.A1971 </span></div>
  
  
  
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<div id="hw-article-author-popups-top-node-9910--61855567990" style="display: none;"><div class="author-tooltip-0"><div class="author-tooltip-name">S. Diekmann </div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=S.%2BDiekmann%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Diekmann%20S&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AS.%2BDiekmann%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-1"><div class="author-tooltip-name">E. 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<p id="p-3"><strong>BACKGROUND AND PURPOSE:</strong> Recently introduced 320-detector row CT enables whole brain perfusion imaging compared to a limited scanning area in 64-detector row CT. Our aim was to evaluate patient radiation exposure in comprehensive stroke imaging by using multidetector row CT consisting of standard CT of the head, CTA of cerebral and cervical vessels, and CTP.</p>
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<p id="p-4"><strong>MATERIAL AND METHODS:</strong> Organ doses were measured by using LiF-TLDs located at several organ sites in an Alderson-Rando phantom. Effective doses were derived from these measurements. Stroke protocols including noncontrast head CT, CTA of cerebral and cervical vessels, and CTP were performed on 320- and 64-detector row scanners.</p>
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<p id="p-5"><strong>RESULTS:</strong> Measured effective doses for the different scanning protocols ranged between 1.61 and 4.56 mSv, resulting in an effective dose for complete stroke imaging of 7.52/7.54 mSv (m/f) for 64-detector row CT and 10.56/10.6 mSv (m/f) for 320-detector row CT. The highest organ doses within the area of the primary beam were measured in the skin (92 mGy) and cerebral hemispheres (69.91 mGy). Use of an eye-protection device resulted in a 54% decrease of the lens dose measured for the combo protocol for whole-brain perfusion with the 320-detector row CT scanner.</p>
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<p id="p-6"><strong>CONCLUSIONS:</strong> Phantom measurements indicate that comprehensive stroke imaging with multidetector row CT may result in effective radiation doses from 7.52 mSv (64-detector row CT) to 10.6 mSv (320-detector row CT). The technique of 320-detector row CT offers additional information on the time course of vascular enhancement and whole-brain perfusion. Physicians should weigh the potential of the new technique against the higher radiation dose that is needed. Critical doses that would cause organ damage were not reached.</p>
</div></div><div class="section glossary" id="glossary-1"><h2>Abbreviations</h2><dl id="def-list-1"><dt id="def-item-1">CCT<span class="def-item-dt-sep"></span></dt><dd>cerebral CT<span class="def-item-dd-sep"></span></dd><dt id="def-item-2">CTA<span class="def-item-dt-sep"></span></dt><dd>CT angiography<span class="def-item-dd-sep"></span></dd><dt id="def-item-3">CTDI<span class="def-item-dt-sep"></span></dt><dd>CT Dose Index<span class="def-item-dd-sep"></span></dd><dt id="def-item-4">CTP<span class="def-item-dt-sep"></span></dt><dd>CT perfusion<span class="def-item-dd-sep"></span></dd><dt id="def-item-5">ICA<span class="def-item-dt-sep"></span></dt><dd>internal carotid artery<span class="def-item-dd-sep"></span></dd><dt id="def-item-6">ICRP<span class="def-item-dt-sep"></span></dt><dd>International Commission on Radiological Protection<span class="def-item-dd-sep"></span></dd><dt id="def-item-7">LiF<span class="def-item-dt-sep"></span></dt><dd>lithium-fluoride<span class="def-item-dd-sep"></span></dd><dt id="def-item-8">mAs<sub>eff</sub><span class="def-item-dt-sep"></span></dt><dd>effective milliampere-second<span class="def-item-dd-sep"></span></dd><dt id="def-item-9">m/f<span class="def-item-dt-sep"></span></dt><dd>male/female<span class="def-item-dd-sep"></span></dd><dt id="def-item-10">PMMA<span class="def-item-dt-sep"></span></dt><dd>polymethylmethacrylate<span class="def-item-dd-sep"></span></dd><dt id="def-item-11">TLD<span class="def-item-dt-sep"></span></dt><dd>thermoluminescent dosimeter<span class="def-item-dd-sep"></span></dd><dt id="def-item-12">W (T)<span class="def-item-dt-sep"></span></dt><dd>weighting factor</dd></dl></div><ul class="copyright-statement"><li class="fn" id="copyright-statement-1">Copyright © American Society of Neuroradiology</li></ul><span class="highwire-journal-article-marker-end"></span></div><span class="related-urls"></span></div><a href="http://ajnr-stage2.stage.highwire.org/content/31/6/1003.full" class="hw-link hw-link-article-full-text" data-icon-position="" data-hide-link-title="0">View Full Text</a></div>  </div>

  
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    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">Jun 2010, </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">31 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(6) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">1003-1009; </span><span  class="highwire-cite-metadata-doi highwire-cite-metadata"><span class="label">DOI:</span> 10.3174/ajnr.A1971 </span></div>
  
  
  
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    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">Jun 2010, </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">31 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(6) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">1003-1009; </span><span  class="highwire-cite-metadata-doi highwire-cite-metadata"><span class="label">DOI:</span> 10.3174/ajnr.A1971 </span></div>
  
  
  
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