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<meta name="DC.Description" content="SUMMARY: In this report, we present the fatal spontaneous delayed rupture of a previously unruptured large PICA aneurysm following treatment with the PED. Pathology at postmortem examination has supported the theory that intra-aneurysmal thrombus may acutely destabilize the aneurysm wall. Aneurysms with an anatomic arrangement that promote continued flow into the neck may not be optimal candidates for the flow-diversion treatment strategy.

AAA
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AS
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B
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HE
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ILT
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LAIC
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LV
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M
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MRA
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P
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PED
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PICA
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pO2
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&lt;p&gt;In this report, we present the fatal spontaneous delayed rupture of a previously unruptured large PICA aneurysm following treatment with the PED. Pathology at postmortem examination has supported the theory that intra-aneurysmal thrombus may acutely destabilize the aneurysm wall. Aneurysms with an anatomic arrangement that promote continued flow into the neck may not be optimal candidates for the flow-diversion treatment strategy.&lt;/p&gt;" />
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<meta name="twitter:title" content="Delayed Spontaneous Rupture of a Posterior Inferior Cerebellar Artery Aneurysm Following Treatment with Flow Diversion: A Clinicopathologic Study" />
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<meta name="twitter:description" content="SUMMARY: In this report, we present the fatal spontaneous delayed rupture of a previously unruptured large PICA aneurysm following treatment with the PED. Pathology at postmortem examination has supported the theory that intra-aneurysmal thrombus may acutely destabilize the aneurysm wall. Aneurysms with an anatomic arrangement that promote continued flow into the neck may not be optimal candidates for the flow-diversion treatment strategy.

AAA
:   abdominal aortic aneurysm
AS
:   anterior spinal artery
B
:   basilar
HE
:   hematoxylin-eosin
ILT
:   intraluminal thrombus
LAIC
:   left anterior inferior cerebellar artery
LV
:   left vertebral artery
M
:   medulla
MRA
:   MR angiography
P
:   pons
PED
:   Pipeline Embolization Device
PICA
:   posterior inferior cerebellar artery
pO2
:   partial pressure of oxygen
POD
:   postoperative day
RPIC
:   right posterior inferior cerebellar artery
RV
:   right vertebral artery" />
<meta name="og-title" property="og:title" content="Delayed Spontaneous Rupture of a Posterior Inferior Cerebellar Artery Aneurysm Following Treatment with Flow Diversion: A Clinicopathologic Study" />
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<meta name="og-site-name" property="og:site_name" content="American Journal of Neuroradiology" />
<meta name="og-description" property="og:description" content="SUMMARY: In this report, we present the fatal spontaneous delayed rupture of a previously unruptured large PICA aneurysm following treatment with the PED. Pathology at postmortem examination has supported the theory that intra-aneurysmal thrombus may acutely destabilize the aneurysm wall. Aneurysms with an anatomic arrangement that promote continued flow into the neck may not be optimal candidates for the flow-diversion treatment strategy.

AAA
:   abdominal aortic aneurysm
AS
:   anterior spinal artery
B
:   basilar
HE
:   hematoxylin-eosin
ILT
:   intraluminal thrombus
LAIC
:   left anterior inferior cerebellar artery
LV
:   left vertebral artery
M
:   medulla
MRA
:   MR angiography
P
:   pons
PED
:   Pipeline Embolization Device
PICA
:   posterior inferior cerebellar artery
pO2
:   partial pressure of oxygen
POD
:   postoperative day
RPIC
:   right posterior inferior cerebellar artery
RV
:   right vertebral artery" />
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      <h1 class="highwire-cite-title" id="page-title">Delayed Spontaneous Rupture of a Posterior Inferior Cerebellar Artery Aneurysm Following Treatment with Flow Diversion: A Clinicopathologic Study</h1>  
    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0">M. Chow</span>, <span class="highwire-citation-author" data-delta="1">C. McDougall</span>, <span class="highwire-citation-author" data-delta="2">C. O'Kelly</span>, <span class="highwire-citation-author" data-delta="3">R. Ashforth</span>, <span class="highwire-citation-author" data-delta="4">E. Johnson</span> and <span class="highwire-citation-author" data-delta="5">D. Fiorella</span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">April 2012,  </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">33 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(4) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">E46-E51; </span><span  class="highwire-cite-metadata-doi highwire-cite-metadata">DOI: https://doi.org/10.3174/ajnr.A2532 </span></div>
  
  
  
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<div id="hw-article-author-popups-top-node-11861--61755819788" style="display: none;"><div class="author-tooltip-0"><div class="author-tooltip-name">M. Chow </div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=M.%2BChow%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Chow%20M&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AM.%2BChow%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-1"><div class="author-tooltip-name">C. 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Ashforth </div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=R.%2BAshforth%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Ashforth%20R&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AR.%2BAshforth%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-4"><div class="author-tooltip-name">E. 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<p id="p-1"><strong>SUMMARY:</strong> In this report, we present the fatal spontaneous delayed rupture of a previously unruptured large PICA aneurysm following treatment with the PED. Pathology at postmortem examination has supported the theory that intra-aneurysmal thrombus may acutely destabilize the aneurysm wall. Aneurysms with an anatomic arrangement that promote continued flow into the neck may not be optimal candidates for the flow-diversion treatment strategy.</p>
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<h2>ABBREVIATIONS:</h2>
<dl id="def-list-1"><dt id="def-item-1">AAA<span class="def-item-dt-sep"></span></dt><dd>abdominal aortic aneurysm<span class="def-item-dd-sep"></span></dd><dt id="def-item-2">AS<span class="def-item-dt-sep"></span></dt><dd>anterior spinal artery<span class="def-item-dd-sep"></span></dd><dt id="def-item-3">B<span class="def-item-dt-sep"></span></dt><dd>basilar<span class="def-item-dd-sep"></span></dd><dt id="def-item-4">HE<span class="def-item-dt-sep"></span></dt><dd>hematoxylin-eosin<span class="def-item-dd-sep"></span></dd><dt id="def-item-5">ILT<span class="def-item-dt-sep"></span></dt><dd>intraluminal thrombus<span class="def-item-dd-sep"></span></dd><dt id="def-item-6">LAIC<span class="def-item-dt-sep"></span></dt><dd>left anterior inferior cerebellar artery<span class="def-item-dd-sep"></span></dd><dt id="def-item-7">LV<span class="def-item-dt-sep"></span></dt><dd>left vertebral artery<span class="def-item-dd-sep"></span></dd><dt id="def-item-8">M<span class="def-item-dt-sep"></span></dt><dd>medulla<span class="def-item-dd-sep"></span></dd><dt id="def-item-9">MRA<span class="def-item-dt-sep"></span></dt><dd>MR angiography<span class="def-item-dd-sep"></span></dd><dt id="def-item-10">P<span class="def-item-dt-sep"></span></dt><dd>pons<span class="def-item-dd-sep"></span></dd><dt id="def-item-11">PED<span class="def-item-dt-sep"></span></dt><dd>Pipeline Embolization Device<span class="def-item-dd-sep"></span></dd><dt id="def-item-12">PICA<span class="def-item-dt-sep"></span></dt><dd>posterior inferior cerebellar artery<span class="def-item-dd-sep"></span></dd><dt id="def-item-13">pO<sub>2</sub><span class="def-item-dt-sep"></span></dt><dd>partial pressure of oxygen<span class="def-item-dd-sep"></span></dd><dt id="def-item-14">POD<span class="def-item-dt-sep"></span></dt><dd>postoperative day<span class="def-item-dd-sep"></span></dd><dt id="def-item-15">RPIC<span class="def-item-dt-sep"></span></dt><dd>right posterior inferior cerebellar artery<span class="def-item-dd-sep"></span></dd><dt id="def-item-16">RV<span class="def-item-dt-sep"></span></dt><dd>right vertebral artery</dd></dl>
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    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">Apr 2012, </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">33 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(4) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">E46-E51; </span><span  class="highwire-cite-metadata-doi highwire-cite-metadata"><span class="label">DOI:</span> 10.3174/ajnr.A2532 </span></div>
  
  
  
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