Index by author
Qian, T.Y.
- EDITOR'S CHOICEBrainOpen AccessMapping p53 Mutations in Low-Grade Glioma: A Voxel-Based Neuroimaging AnalysisY.Y. Wang, T. Zhang, S.W. Li, T.Y. Qian, X. Fan, X.X. Peng, J. Ma, L. Wang and T. JiangAmerican Journal of Neuroradiology January 2015, 36 (1) 70-76; DOI: https://doi.org/10.3174/ajnr.A4065
Brain tumor location has prognostic implications so these authors explored whether location also correlated with p53 status in 182 patients. Tumors occurring in the left medial temporal and right anterior temporal lobes were associated with high expression of mutant p53 and had significantly worse progression-free survival.
Qiu, Y.-w.
- EDITOR'S CHOICEBrainOpen AccessAbnormal White Matter Integrity in Chronic Users of Codeine-Containing Cough Syrups: A Tract-Based Spatial Statistics StudyY.-w. Qiu, H.-h. Su, X.-f. Lv and G.-h. JiangAmerican Journal of Neuroradiology January 2015, 36 (1) 50-56; DOI: https://doi.org/10.3174/ajnr.A4070
Because codeine is a popular drug and results in cognitive deficits, the authors assessed 30 chronic users and 30 controls with DTI. Chronic codeine users showed lower fractional anisotropy in 4 brain regions and higher scores on the Barratt Impulsiveness Scale. It appears that chronic codeine-containing syrup abuse may be associated with disruptions in brain white matter integrity and that these microstructural deficits may be linked to higher impulsivity in chronic users.