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    Index by author — December 01, 2015, 36 (12) | American Journal of Neuroradiology  
    
















    





















    
  
  




    
    

  

      


    

      

  
  
  

    

  

    

  

                
    

      

  

    

  
      
  
  

    


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Index by author
  	
      
December 01, 2015; Volume 36,Issue 12 

  
  
   

  
  



  


  
  



			

		

	
	
 	
	  
  

		
		

			

			  

  
      
  
  

    
  1. Ishikawa, M.
    1. 
  
  
      
      FELLOWS' JOURNAL CLUBADULT BRAIN 
      
  
      
      Open Access
      
  
      Optimal Diagnostic Indices for Idiopathic Normal Pressure Hydrocephalus Based on the 3D Quantitative Volumetric Analysis for the Cerebral Ventricle and Subarachnoid Space  
    	
      S. Yamada, M. Ishikawa and K. Yamamoto
      
  
    	
      American Journal of Neuroradiology December 2015, 36 (12) 2262-2269; DOI: https://doi.org/10.3174/ajnr.A4440 
      
  
    	
      Patients with suspected idiopathic normal pressure hydrocephalus (NPH) on the basis of the ventriculomegaly and a triad of symptoms underwent the CSF tap test. CSF volumes were extracted from a T2-weighted 3D spin-echo SPACE sequence on 3T MR imaging and were quantified semiautomatically. Twenty-four patients with tap-positive idiopathic NPH, 25 patients without response to the tap test, and 23 age-matched controls were included. The CSF volume of the parietal convexity had the highest area under the ROC curve in the discrimination of the tap-test response (0.768), followed by the z-Evans Index (0.758), and the upper-to-lower subarachnoid space ratio index (0.723). CSF volume of the parietal convexity of less than 38 mL, upper-to-lower subarachnoid space ratio of less than 0.33, and a z-Evans Index of greater than 0.42 are the newly proposed useful indices for idiopathic NPH diagnosis.
      
  
  

      

  


  
  



  
      
  
  

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