Index by author
Laiwalla, A.N.
- EDITOR'S CHOICEADULT BRAINOpen AccessEvaluation of Encephaloduroarteriosynangiosis Efficacy Using Probabilistic Independent Component Analysis Applied to Dynamic Susceptibility Contrast Perfusion MRIA.N. Laiwalla, F. Kurth, K. Leu, R. Liou, J. Pamplona, Y.C. Ooi, N. Salamon, B.M. Ellingson and N.R. GonzalezAmerican Journal of Neuroradiology March 2017, 38 (3) 507-514; DOI: https://doi.org/10.3174/ajnr.A5041
In this prospective study, 13 patients underwent unilateral indirect cerebral revascularization and DSC-MR imaging before and after surgery. Conventional perfusion parameters (relative CBV, relative CBF, and TTP) and probabilistic independent components that reflect the relative contributions of DSC signals consistent with arterial, capillary, and venous hemodynamics were calculated and examined for significant changes after surgery. Before surgery, tissue within the affected hemisphere demonstrated a high probability for hemodynamics consistent with venous flow and a low probability for hemodynamics consistent with arterial flow, whereas the contralateral control hemisphere demonstrated the reverse. Consistent with symptomatic improvement, the probability for venous hemodynamics within the affected hemisphere decreased with time after surgery. The authors conclude that probabilistic independent component analysis yielded sensitive measurements of changes in local tissue perfusion that may be associated with newly formed vasculature after indirect cerebral revascularization surgery
Lang, S.
- INTERVENTIONALYou have accessFRED Flow Diverter: A Study on Safety and Efficacy in a Consecutive Group of 50 PatientsH. Luecking, T. Engelhorn, S. Lang, P. Goelitz, S. Kloska, K. Roessler and A. DoerflerAmerican Journal of Neuroradiology March 2017, 38 (3) 596-602; DOI: https://doi.org/10.3174/ajnr.A5052
Lanthier, S.
- EDITOR'S CHOICEINTERVENTIONALOpen AccessHydrogel versus Bare Platinum Coils in Patients with Large or Recurrent Aneurysms Prone to Recurrence after Endovascular Treatment: A Randomized Controlled TrialJ. Raymond, R. Klink, M. Chagnon, S.L. Barnwell, A.J. Evans, J. Mocco, B.H. Hoh, A.S. Turk, R.D. Turner, H. Desal, D. Fiorella, S. Bracard, A. Weill, F. Guilbert, S. Lanthier, A.J. Fox, T.E. Darsaut, P.M. White and D. RoyAmerican Journal of Neuroradiology March 2017, 38 (3) 432-441; DOI: https://doi.org/10.3174/ajnr.A5101
This Level 1 expedited report was a pragmatic, multicenter, parallel, randomized (1:1) trial evaluating patients who were at high risk of aneurysm recurrence after endovascular treatment, including patients with large aneurysms (Patients Prone to Recurrence After Endovascular Treatment PRET-1) or with aneurysms that had previously recurred after coiling (PRET-2). The trial was stopped once 250 patients in PRET-1 and 197 in PRET-2 had been recruited because of slow accrual. A poor primary outcome occurred in 44.4% of those in PRET-1 allocated to platinum compared with 52.5% of patients allocated to hydrogel and in 49.0% in PRET-2 allocated to platinum compared with 42.1% allocated to hydrogel. Adverse events and morbidity were similar. The authors conclude that coiling of large and recurrent aneurysms is safe but often poorly effective according to angiographic results. Hydrogel coiling was not shown to be better than platinum.
Larroza, A.
- You have accessComment on “Computer-Extracted Texture Features to Distinguish Cerebral Radionecrosis from Recurrent Brain Tumors on Multiparametric MRI: A Feasibility Study”A. Larroza, D. Moratal, A. Paredes-Sánchez, E. Soria-Olivas, M.L. Chust, L.A. Arribas and E. AranaAmerican Journal of Neuroradiology March 2017, 38 (3) E21; DOI: https://doi.org/10.3174/ajnr.A5071
Lee, I.H.
- You have accessReply:I.H. Lee, D.M. Kim and C.J. SongAmerican Journal of Neuroradiology March 2017, 38 (3) E25; DOI: https://doi.org/10.3174/ajnr.A5077
Lee, M.
- ADULT BRAINOpen AccessDiagnostic Accuracy of T1-Weighted Dynamic Contrast-Enhanced–MRI and DWI-ADC for Differentiation of Glioblastoma and Primary CNS LymphomaX. Lin, M. Lee, O. Buck, K.M. Woo, Z. Zhang, V. Hatzoglou, A. Omuro, J. Arevalo-Perez, A.A. Thomas, J. Huse, K. Peck, A.I. Holodny and R.J. YoungAmerican Journal of Neuroradiology March 2017, 38 (3) 485-491; DOI: https://doi.org/10.3174/ajnr.A5023
Leu, K.
- FELLOWS' JOURNAL CLUBADULT BRAINYou have accessEffects of MRI Protocol Parameters, Preload Injection Dose, Fractionation Strategies, and Leakage Correction Algorithms on the Fidelity of Dynamic-Susceptibility Contrast MRI Estimates of Relative Cerebral Blood Volume in GliomasK. Leu, J.L. Boxerman and B.M. EllingsonAmerican Journal of Neuroradiology March 2017, 38 (3) 478-484; DOI: https://doi.org/10.3174/ajnr.A5027
The authors used DSC-MR imaging simulations to examine the influence of various acquisition parameters and leakage-correction strategies on the faithful estimation of CBV. Optimal strategies were determined by protocol with the lowest mean error. They conclude that the choice of image acquisition and preload dosing and/or fractionation has tremendous impact on the fidelity of CBV estimation. A variety of acquisition strategies can be used to obtain similar accuracy of CBV estimation, while the bidirectional leakage-correction algorithm aids in minimizing errors in CBV estimation under all scenarios.
- EDITOR'S CHOICEADULT BRAINOpen AccessEvaluation of Encephaloduroarteriosynangiosis Efficacy Using Probabilistic Independent Component Analysis Applied to Dynamic Susceptibility Contrast Perfusion MRIA.N. Laiwalla, F. Kurth, K. Leu, R. Liou, J. Pamplona, Y.C. Ooi, N. Salamon, B.M. Ellingson and N.R. GonzalezAmerican Journal of Neuroradiology March 2017, 38 (3) 507-514; DOI: https://doi.org/10.3174/ajnr.A5041
In this prospective study, 13 patients underwent unilateral indirect cerebral revascularization and DSC-MR imaging before and after surgery. Conventional perfusion parameters (relative CBV, relative CBF, and TTP) and probabilistic independent components that reflect the relative contributions of DSC signals consistent with arterial, capillary, and venous hemodynamics were calculated and examined for significant changes after surgery. Before surgery, tissue within the affected hemisphere demonstrated a high probability for hemodynamics consistent with venous flow and a low probability for hemodynamics consistent with arterial flow, whereas the contralateral control hemisphere demonstrated the reverse. Consistent with symptomatic improvement, the probability for venous hemodynamics within the affected hemisphere decreased with time after surgery. The authors conclude that probabilistic independent component analysis yielded sensitive measurements of changes in local tissue perfusion that may be associated with newly formed vasculature after indirect cerebral revascularization surgery
Lin, F.-H.
- FUNCTIONALOpen AccessHippocampal Atrophy Is Associated with Altered Hippocampus–Posterior Cingulate Cortex Connectivity in Mesial Temporal Lobe Epilepsy with Hippocampal SclerosisY.C. Shih, C.E. Tseng, F.-H. Lin, H.H. Liou and W.Y.I. TsengAmerican Journal of Neuroradiology March 2017, 38 (3) 626-632; DOI: https://doi.org/10.3174/ajnr.A5039
Lin, X.
- ADULT BRAINOpen AccessDiagnostic Accuracy of T1-Weighted Dynamic Contrast-Enhanced–MRI and DWI-ADC for Differentiation of Glioblastoma and Primary CNS LymphomaX. Lin, M. Lee, O. Buck, K.M. Woo, Z. Zhang, V. Hatzoglou, A. Omuro, J. Arevalo-Perez, A.A. Thomas, J. Huse, K. Peck, A.I. Holodny and R.J. YoungAmerican Journal of Neuroradiology March 2017, 38 (3) 485-491; DOI: https://doi.org/10.3174/ajnr.A5023
Liou, H.H.
- FUNCTIONALOpen AccessHippocampal Atrophy Is Associated with Altered Hippocampus–Posterior Cingulate Cortex Connectivity in Mesial Temporal Lobe Epilepsy with Hippocampal SclerosisY.C. Shih, C.E. Tseng, F.-H. Lin, H.H. Liou and W.Y.I. TsengAmerican Journal of Neuroradiology March 2017, 38 (3) 626-632; DOI: https://doi.org/10.3174/ajnr.A5039



