American Journal of Neuroradiology: 39 (1)

American Journal of Neuroradiology

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Index by author

January 01, 2018; Volume 39,Issue 1

Huang, Q.
1. Interventional
  
  Open Access
  Hemodynamic Changes Caused by Multiple Stenting in Vertebral Artery Fusiform Aneurysms: A Patient-Specific Computational Fluid Dynamics Study
  N. Lv, W. Cao, I. Larrabide, C. Karmonik, D. Zhu, J. Liu, Q. Huang and Y. Fang
  
  American Journal of Neuroradiology January 2018, 39 (1) 118-122; DOI: https://doi.org/10.3174/ajnr.A5452
Huston, J.
1. EDITOR'S CHOICEAdult Brain
  
  Open Access
  MR Elastography Analysis of Glioma Stiffness and IDH1-Mutation Status
  K.M. Pepin, K.P. McGee, A. Arani, D.S. Lake, K.J. Glaser, A. Manduca, I.F. Parney, R.L. Ehman and J. Huston
  
  American Journal of Neuroradiology January 2018, 39 (1) 31-36; DOI: https://doi.org/10.3174/ajnr.A5415
  
  Tumor stiffness properties were prospectively quantified in 18 patients with histologically proved gliomas using MR elastography. Images were acquired on a 3T MR imaging unit with a vibration frequency of 60 Hz. Tumor stiffness was compared with unaffected contralateral white matter, across tumor grade, and by IDH1-mutation status. Gliomas were softer than healthy brain parenchyma, 2.2kPa compared with 3.3kPa, with grade IV tumors softer than grade II. MR elastography demonstrated that not only were gliomas softer than normal brain but the degree of softening was directly correlated with tumor grade and IDH1-mutation status.
Hwang, W.-T.
1. EDITOR'S CHOICEHead & Neck
  
  Open Access
  Dynamic Contrast-Enhanced MRI–Derived Intracellular Water Lifetime (τ_i): A Prognostic Marker for Patients with Head and Neck Squamous Cell Carcinomas
  S. Chawla, L.A. Loevner, S.G. Kim, W.-T. Hwang, S. Wang, G. Verma, S. Mohan, V. LiVolsi, H. Quon and H. Poptani
  
  American Journal of Neuroradiology January 2018, 39 (1) 138-144; DOI: https://doi.org/10.3174/ajnr.A5440
  
  The authors evaluated 60 patients with dynamic contrast-enhanced MR imaging before treatment. Median, mean intracellular water molecule lifetime, and volume transfer constant values from metastatic nodes were computed from each patient. Kaplan-Meier analyses were performed to associate mean intracellular water molecule lifetime and volume transfer constant and their combination with overall survival and beyond. Patients with high mean intracellular water molecule lifetime had overall survival significantly prolonged by 5 years compared with those with low mean intracellular water molecule lifetime. Patients with high mean intracellular water molecule lifetime had significantly longer overall survival at long-term duration than those with low mean intracellular water molecule lifetime. Volume transfer constant was a significant predictor for only the 5-year follow-up period. They conclude that a combined analysis of mean intracellular water molecule lifetime and volume transfer constant provided the best model to predict overall survival in patients with squamous cell carcinomas of the head and neck.

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Huang, Q.

Huston, J.

Hwang, W.-T.

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