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    Index by author — December 01, 2019, 40 (12) | American Journal of Neuroradiology  
    
















    





















    
  
  




    
    

  

      


    

      

  
  
  

    

  

    

  

                
    

      

  

    

  
      
  
  

    


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Index by author
  	
      
December 01, 2019; Volume 40,Issue 12 

  
  
   

  
  



  


  
  



			

		

	
	
 	
	  
  

		
		

			

			  

  
      
  
  

    
  1. Zwartbol, M.H.T.
    1. 
  
  
      
      EDITOR'S CHOICEAdult Brain 
      
  
      
      Open Access
      
  
      Intracranial Atherosclerotic Burden on 7T MRI Is Associated with Markers of Extracranial Atherosclerosis: The SMART-MR Study  
    	
      M.H.T. Zwartbol, M.I. Geerlings, R. Ghaznawi, J. Hendrikse, A.G. van der Kolk and on behalf of the UCC-SMART Study Group
      
  
    	
      American Journal of Neuroradiology December 2019, 40 (12) 2016-2022; DOI: https://doi.org/10.3174/ajnr.A6308 
      
  
    	
      Intracranial atherosclerosis, a major risk factor for ischemic stroke, is thought to have different atherogenic mechanisms than extracranial atherosclerosis. Studies investigating their relationship in vivo are sparse and report inconsistent results. Within the Second Manifestations of ARTerial disease–Magnetic Resonance (SMART) Study, cross-sectional analyses were performed in 130 patients with a history of vascular disease and with assessable 7T intracranial vessel wall MR imaging data. Intracranial atherosclerosis burden was defined as the number of intracranial vessel wall lesions in the circle of Willis and its major branches. Significant associations were observed between higher intracranial atherosclerosis burden and carotid intima-media thickness, 50%–100% carotid stenosis versus no stenosis, ankle-brachial index, and estimated glomerular filtration rate. No significant differences in intracranial atherosclerosis burden were found among different categories of vascular disease.
      
  
  

      

  


  
  



  
      
  
  

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