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      <h1 class="highwire-cite-title" id="page-title">High-Pass-Filtered Phase Image: Left- versus Right-Handed MR Imaging Systems</h1>  
    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0">T.M. Mehemed</span> and <span class="highwire-citation-author" data-delta="1">A. Yamamoto</span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">June 2013,  </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">34 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(6) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">E72; </span><span  class="highwire-cite-metadata-doi highwire-cite-metadata">DOI: https://doi.org/10.3174/ajnr.A3571 </span></div>
  
  
  
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<div id="hw-article-author-popups-node-12514--21059188183" style="display: none;"><div class="author-tooltip-0"><div class="author-tooltip-name">T.M. Mehemed </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>a</span>Department of Diagnostic Imaging and Nuclear Medicine
Kyoto University Graduate School of Medicine
Kyoto, Japan</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=T.M.%2BMehemed%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Mehemed%20T&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AT.M.%2BMehemed%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-1"><div class="author-tooltip-name">A. Yamamoto </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>a</span>Department of Diagnostic Imaging and Nuclear Medicine
Kyoto University Graduate School of Medicine
Kyoto, Japan</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=A.%2BYamamoto%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Yamamoto%20A&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AA.%2BYamamoto%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div></div></div>  </div>

  
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    <div class="highwire-markup"><div xmlns="http://www.w3.org/1999/xhtml" data-highwire-cite-ref-tooltip-instance="highwire_reflinks_tooltip" class="content-block-markup" xmlns:xhtml="http://www.w3.org/1999/xhtml"><div class="article fulltext-view "><span class="highwire-journal-article-marker-start"></span><p id="p-1">We read with interest the article entitled “Detection of Intratumoral Calcification in Oligodendrogliomas by Susceptibility-Weighted MR Imaging”<sup><a id="xref-ref-1-1" class="xref-bibr" href="#ref-1">1</a></sup> and would like to comment on the appearance of calcification on the high-pass-filtered phase images.</p><p id="p-2">The authors reported that the paramagnetic (authors wrote “diamagnetic”) hemorrhagic component of the tumor would cause a negative phase shift and appear as dark signal on the high-pass-filtered phase images, while the diamagnetic (authors wrote “paramagnetic”) intratumoral calcifications would cause an opposite positive phase shift and appear as bright signal on the high-pass-filtered phase images. This description is true, but only in the case of right-handed MR imaging systems, while in left-handed MR imaging systems, the complete opposite signal would be seen: Paramagnetic substances would appear bright, while diamagnetic substances would appear dark.<sup><a id="xref-ref-2-1" class="xref-bibr" href="#ref-2">2</a>,<a id="xref-ref-3-1" class="xref-bibr" href="#ref-3">3</a></sup></p><p id="p-3">In Figs 2<em>D</em> and 3<em>D</em> of the above-mentioned article, the high-pass-filtered phase images are those of a left-handed MR imaging system, evident by the bright signal of the veins (paramagnetic deoxyhemoglobin).<sup><a id="xref-ref-3-2" class="xref-bibr" href="#ref-3">3</a></sup></p><p id="p-4">The article showed that high-pass-filtered phase images can depict intratumoral calcification in oligodendrogliomas better than conventional MR images; this finding has been reported before.<sup><a id="xref-ref-4-1" class="xref-bibr" href="#ref-4">4</a></sup> Understanding the contrast appearance of high-pass-filtered phase images on left-handed versus right-handed MR imaging systems would make distinguishing diamagnetic calcification from paramagnetic hemorrhage a much easier task and prevent any possible confusion.</p><div class="section ref-list" id="ref-list-1"><h2>REFERENCES</h2><ol class="cit-list ref-use-labels"><li><span class="ref-label">1.</span>

<div class="cit ref-cit ref-journal" id="cit-34.6.E72.1" data-doi="10.3174/ajnr.A2862"><div class="cit-metadata"><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Zulfiqar</span>  <span class="cit-name-given-names">M</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Dumrongpisutikul</span>  <span class="cit-name-given-names">N</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Intrapiromkul</span>  <span class="cit-name-given-names">J</span></span>, </li><li><span class="cit-etal">et al</span></li></ol><cite>. <span class="cit-article-title">Detection of intratumoral calcification in oligodendrogliomas by susceptibility-weighted MR imaging</span>. <abbr class="cit-jnl-abbrev">AJNR Am J Neuroradiol</abbr> <span class="cit-pub-date">2012</span>;<span class="cit-vol">33</span>:<span class="cit-fpage">858</span>–<span class="cit-lpage">64</span></cite></div></div></li><li><span class="ref-label">2.</span>

<div class="cit ref-cit ref-book" id="cit-34.6.E72.2"><div class="cit-metadata"><ol class="duplicate"><li><span class="cit-ed"><span class="cit-name-surname">Haacke</span>  <span class="cit-name-given-names">EM</span></span>, </li><li><span class="cit-ed"><span class="cit-name-surname">Reichenbach</span>  <span class="cit-name-given-names">JR</span></span></li></ol><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Duyn</span>  <span class="cit-name-given-names">J</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Speck</span>  <span class="cit-name-given-names">O</span></span></li></ol><cite>. <span class="cit-article-title">Brain Anatomy with Phase</span>. In: <span class="cit-ed"><span class="cit-name-surname">Haacke</span>  <span class="cit-name-given-names">EM</span></span>, 
<span class="cit-ed"><span class="cit-name-surname">Reichenbach</span>  <span class="cit-name-given-names">JR</span></span>. <span class="cit-source">Susceptibility Weighted Imaging in MRI: Basic Concepts and Clinical Applications</span>. <span class="cit-publ-loc">Hoboken, New Jersey</span>: <span class="cit-publ-name">John Wiley &amp; Sons</span>; <span class="cit-pub-date">2011</span>:<span class="cit-fpage">121</span>–<span class="cit-lpage">36</span></cite></div></div></li><li><span class="ref-label">3.</span>

<div class="cit ref-cit ref-book" id="cit-34.6.E72.3"><div class="cit-metadata"><ol class="duplicate"><li><span class="cit-ed"><span class="cit-name-surname">Haacke</span>  <span class="cit-name-given-names">EM</span></span>, </li><li><span class="cit-ed"><span class="cit-name-surname">Reichenbach</span>  <span class="cit-name-given-names">JR</span></span></li></ol><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Mittal</span>  <span class="cit-name-given-names">S</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Thomas</span>  <span class="cit-name-given-names">B</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Wu</span>  <span class="cit-name-given-names">Z</span></span>, </li><li><span class="cit-etal">et al</span></li></ol><cite>. <span class="cit-article-title">Novel approaches to imaging brain tumors</span>. In: <span class="cit-ed"><span class="cit-name-surname">Haacke</span>  <span class="cit-name-given-names">EM</span></span>, 
<span class="cit-ed"><span class="cit-name-surname">Reichenbach</span>  <span class="cit-name-given-names">JR</span></span>. <span class="cit-source">Susceptibility Weighted Imaging in MRI: Basic Concepts and Clinical Applications</span>. <span class="cit-publ-loc">Hoboken, New Jersey</span>: <span class="cit-publ-name">John Wiley &amp; Sons</span>; <span class="cit-pub-date">2011</span>:<span class="cit-fpage">151</span>–<span class="cit-lpage">70</span></cite></div></div></li><li><span class="ref-label">4.</span>

<div class="cit ref-cit ref-journal" id="cit-34.6.E72.4" data-doi="10.1002/jmri.21617"><div class="cit-metadata"><ol class="cit-auth-list"><li><span class="cit-auth"><span class="cit-name-surname">Wu</span>  <span class="cit-name-given-names">Z</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Mittal</span>  <span class="cit-name-given-names">S</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Kish</span>  <span class="cit-name-given-names">K</span></span>, </li><li><span class="cit-etal">et al</span></li></ol><cite>. <span class="cit-article-title">Identification of calcification with MRI using susceptibility-weighted imaging: a case study</span>. <abbr class="cit-jnl-abbrev">J Magn Reson Imaging</abbr> <span class="cit-pub-date">2009</span>;<span class="cit-vol">29</span>:<span class="cit-fpage">177</span>–<span class="cit-lpage">82</span></cite></div></div></li></ol></div><ul class="copyright-statement"><li class="fn" id="copyright-statement-1">© 2013 by American Journal of Neuroradiology</li></ul><span class="highwire-journal-article-marker-end"></span></div><span class="related-urls"></span></div></div>  </div>

  
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