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    More articles from Adult Brain
  

  
  

			
		
	
	
 	
	  
  
		
		
			
			  
  
      
  
  
    
  
  
      EDITOR'S CHOICEADULT BRAIN 
  
      Open Access
  
      Mitotic Activity in Glioblastoma Correlates with Estimated Extravascular Extracellular Space Derived from Dynamic Contrast-Enhanced MR Imaging  
    	S.J. Mills, D. du Plessis, P. Pal, G. Thompson, G. Buonacorrsi, C. Soh, G.J.M. Parker and A. Jackson
  
    	American Journal of Neuroradiology May 2016, 37 (5) 811-817; DOI: https://doi.org/10.3174/ajnr.A4623 
  
    	Twenty-eight patients with newly presenting glioblastoma multiforme underwent preoperative conventional imaging and T1 dynamic contrast-enhanced MRI. Parametric maps of the initial area under the contrast agent concentration curve, contrast transfer coefficient, estimate of volume of the extravascular extracellular space, and estimate of blood plasma volume were generated, and the enhancing fraction was calculated. High values of the estimate of volume of the extravascular extracellular space were associated with a fibrillary histologic pattern and increased mitotic activity. This finding is counterintuitive to the standard concept that more proliferative tumors would be more densely packed with cells and have less extracellular space. As the authors point out, this surprising finding requires more investigation to understand whether this relationship will hold, and what the underlying mechanism might be.
  
  


  
  
      ADULT BRAIN 
  
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      Quantitative MRI for Rapid and User-Independent Monitoring of Intracranial CSF Volume in Hydrocephalus  
    	J. Virhammar, M. Warntjes, K. Laurell and E.-M. Larsson
  
    	American Journal of Neuroradiology May 2016, 37 (5) 797-801; DOI: https://doi.org/10.3174/ajnr.A4627 
  
  
  


  
  
      FUNCTIONAL 
  
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      Impaired Cerebrovascular Reactivity Predicts Recurrent Symptoms in Patients with Carotid Artery Occlusion: A Hypercapnia BOLD fMRI Study  
    	S.D. Goode, N. Altaf, S. Munshi, S.T.R. MacSweeney and D.P. Auer
  
    	American Journal of Neuroradiology May 2016, 37 (5) 904-909; DOI: https://doi.org/10.3174/ajnr.A4739 
  
  
  


  
  
      FELLOWS' JOURNAL CLUBADULT BRAIN 
  
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      Cough-Associated Changes in CSF Flow in Chiari I Malformation Evaluated by Real-Time MRI  
    	R.A. Bhadelia, S. Patz, C. Heilman, D. Khatami, E. Kasper, Y. Zhao and N. Madan
  
    	American Journal of Neuroradiology May 2016, 37 (5) 825-830; DOI: https://doi.org/10.3174/ajnr.A4629 
  
    	Eight symptomatic patients with Chiari I malformation and 6 healthy participants were studied by using MR pencil beam imaging with a temporal resolution of 50 ms. Patients and healthy participants were scanned in real-time during resting, coughing, and postcoughing periods. CSF flow waveform amplitude, CSF stroke volume, and CSF flow rate were compared between the patients and the control population. Real-time MR imaging noninvasively showed a transient decrease in CSF flow across the foramen magnum after coughing in symptomatic patients with Chiari I malformation.
  
  


  
  
      INTERVENTIONAL 
  
      Open Access
  
      A Systematic Review and Meta-Analysis of Treatment and Outcome of Blister-Like Aneurysms  
    	S. Peschillo, D. Cannizzaro, A. Caporlingua and P. Missori
  
    	American Journal of Neuroradiology May 2016, 37 (5) 856-861; DOI: https://doi.org/10.3174/ajnr.A4606 
  
  
  


  
  
      FUNCTIONAL 
  
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      Different Functional and Microstructural Changes Depending on Duration of Mild Cognitive Impairment in Parkinson Disease  
    	N.-Y. Shin, Y.S. Shin, P.H. Lee, U. Yoon, S. Han, D.J. Kim and S.-K. Lee
  
    	American Journal of Neuroradiology May 2016, 37 (5) 897-903; DOI: https://doi.org/10.3174/ajnr.A4626 
  
  
  


  
  
      ADULT BRAIN 
  
      Open Access
  
      Quantitative Susceptibility Mapping Suggests Altered Brain Iron in Premanifest Huntington Disease  
    	J.M.G. van Bergen, J. Hua, P.G. Unschuld, I.A.L. Lim, C.K. Jones, R.L. Margolis, C.A. Ross, P.C.M. van Zijl and X. Li
  
    	American Journal of Neuroradiology May 2016, 37 (5) 789-796; DOI: https://doi.org/10.3174/ajnr.A4617 
  
  
  


  
  
      ADULT BRAIN 
  
      Open Access
  
      Distinguishing Neuroimaging Features in Patients Presenting with Visual Hallucinations  
    	T.T. Winton-Brown, A. Ting, R. Mocellin, D. Velakoulis and F. Gaillard
  
    	American Journal of Neuroradiology May 2016, 37 (5) 774-781; DOI: https://doi.org/10.3174/ajnr.A4636 
  
  
  


  
  
      ADULT BRAIN 
  
      You have access
  
      Imaging Findings Associated with Space-Occupying Edema in Patients with Large Middle Cerebral Artery Infarcts  
    	A.D. Horsch, J.W. Dankbaar, T.A. Stemerdink, E. Bennink, T. van Seeters, L.J. Kappelle, J. Hofmeijer, H.W. de Jong, Y. van der Graaf and B.K. Velthuis on behalf of the DUST investigators
  
    	American Journal of Neuroradiology May 2016, 37 (5) 831-837; DOI: https://doi.org/10.3174/ajnr.A4637 
  
  
  


  
  
      INTERVENTIONAL 
  
      Open Access
  
      Endovascular Coiling versus Surgical Clipping for Poor-Grade Ruptured Intracranial Aneurysms: Postoperative Complications and Clinical Outcome in a Multicenter Poor-Grade Aneurysm Study  
    	B. Zhao, X. Tan, H. Yang, Z. Li, K. Zheng, Y. Xiong and M. Zhong for the AMPAS Group
  
    	American Journal of Neuroradiology May 2016, 37 (5) 873-878; DOI: https://doi.org/10.3174/ajnr.A4649 
  
  
  

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Print ISSN: 0195-6108 Online ISSN: 1936-959X