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PT  - JOURNAL ARTICLE
AU  - Madakasira, Padma Vasantha
AU  - Simkins, Robert
AU  - Narayanan, Tanjore
AU  - Dunigan, Kelly
AU  - Poelstra, Raymond J.
AU  - Mantil, Joseph
TI  - Cortical Dysplasia Localized by [11C]Methionine Positron Emission Tomography: Case Report
DP  - 2002 May 01
TA  - American Journal of Neuroradiology
PG  - 844--846
VI  - 23
IP  - 5
4099  - http://www.ajnr.org/content/23/5/844.short
4100  - http://www.ajnr.org/content/23/5/844.full
SO  - Am. J. Neuroradiol.2002 May 01; 23
AB  - Summary: Numerous functional neuroimaging techniques have progressively been added to the presurgical evaluation of refractory partial epilepsies. These investigations can help confirm the origin of seizure onset previously suggested by MR imaging and electro-clinical data, provide independent prognostic information, and provide critical diagnostic value when MR imaging results are strictly normal or show multifocal abnormalities. Of the various functional neuroimaging modalities, [11C]methionine positron emission tomography for methionine uptake into seizure foci is still in the preliminary stages of investigation. A single case of medically intractable epilepsy with focal cortical dysplasia documented by [11C]methionine positron emission tomography and possible hypotheses to explain the methionine uptake into the seizure focus are described below.