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PT  - JOURNAL ARTICLE
AU  - Eichler, Florian S.
AU  - Wang, Paul
AU  - Wityk, Robert J.
AU  - Beauchamp, Norman J.
AU  - Barker, Peter B.
TI  - Diffuse Metabolic Abnormalities in Reversible Posterior Leukoencephalopathy Syndrome
DP  - 2002 May 01
TA  - American Journal of Neuroradiology
PG  - 833--837
VI  - 23
IP  - 5
4099  - http://www.ajnr.org/content/23/5/833.short
4100  - http://www.ajnr.org/content/23/5/833.full
SO  - Am. J. Neuroradiol.2002 May 01; 23
AB  - Summary: Two cases of reversible posterior leukoencephalopathy syndrome were examined with proton MR spectroscopic imaging. Widespread metabolic abnormalities, consisting of increased choline and creatine levels and mildly decreased N-acetylaspartate, occurred in regions with both normal and abnormal MR imaging appearances. In one case for which proton MR spectroscopic imaging follow-up was available, all metabolite levels had returned to normal by 2 months. Proton MR spectroscopic imaging may be helpful for the diagnosis and investigation of the underlying pathophysiology of reversible posterior leukoencephalopathy syndrome.