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PT  - JOURNAL ARTICLE
AU  - Hsu, C.C.-T.
AU  - Krings, T.
TI  - Symptomatic Developmental Venous Anomaly: State-of-the-Art Review on Genetics, Pathophysiology, and Imaging Approach to Diagnosis
AID  - 10.3174/ajnr.A7829
DP  - 2023 May 01
TA  - American Journal of Neuroradiology
PG  - 498--504
VI  - 44
IP  - 5
4099  - http://www.ajnr.org/content/44/5/498.short
4100  - http://www.ajnr.org/content/44/5/498.full
SO  - Am. J. Neuroradiol.2023 May 01; 44
AB  - SUMMARY: Developmental venous anomalies (DVAs) are the most common slow-flow venous malformation in the brain. Most DVAs are benign. Uncommonly, DVAs can become symptomatic, leading to a variety of different pathologies. DVAs can vary significantly in size, location, and angioarchitecture, and imaging evaluation of symptomatic developmental venous anomalies requires a systematic approach. In this review, we aimed to provide neuroradiologists with a succinct overview of the genetics and categorization of symptomatic DVAs based on the pathogenesis, which forms the foundation for a tailored neuroimaging approach to assist in diagnosis and management.BRBNSblue rubber bleb nevus syndromeCCMcerebral cavernous malformationCMMRDconstitutional mismatch repair deficiency syndromeCVMScerebrofacial venous metameric syndromeDVAdevelopmental venous anomalyWMHwhite matter hyperintensities