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PT  - JOURNAL ARTICLE
AU  - Mascalchi, Mario
AU  - Belli, Giacomo
AU  - Guerrini, Laura
AU  - Nistri, Marco
AU  - Del Seppia, Ines
AU  - Villari, Natale
TI  - Proton MR Spectroscopy of Wernicke Encephalopathy
DP  - 2002 Nov 01
TA  - American Journal of Neuroradiology
PG  - 1803--1806
VI  - 23
IP  - 10
4099  - http://www.ajnr.org/content/23/10/1803.short
4100  - http://www.ajnr.org/content/23/10/1803.full
SO  - Am. J. Neuroradiol.2002 Nov 01; 23
AB  - Summary: Two patients with acute thiamine deficiency were examined with thalamic single-voxel proton MR spectroscopy. T2-weighted images exhibited increased signal intensity. N-acetylaspartate (NAA)/creatine (Cr) ratios were low without detectable lactate. Owing to substantially decreased choline (Cho) T2, the Cho/Cr ratio was not decreased. After thiamine therapy, the NAA/Cr ratio increased, paralleling clinical improvement and reduction in the areas of signal-intensity changes.