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PT  - JOURNAL ARTICLE
AU  - de Abreu, Marcelo R.
AU  - Chung, Christine B.
AU  - Biswal, Sandip
AU  - Haghighi, Parvis
AU  - Hesselink, John
AU  - Resnick, Donald
TI  - Erdheim-Chester Disease: MR Imaging, Anatomic, and Histopathologic Correlation of Orbital Involvement
DP  - 2004 Apr 01
TA  - American Journal of Neuroradiology
PG  - 627--630
VI  - 25
IP  - 4
4099  - http://www.ajnr.org/content/25/4/627.short
4100  - http://www.ajnr.org/content/25/4/627.full
SO  - Am. J. Neuroradiol.2004 Apr 01; 25
AB  - Summary: Erdheim-Chester disease (ECD) is a rare form of histiocytosis of unknown origin characterized by tissue infiltration by lipid-laden histiocytes. Typically, the diaphyseal and metaphyseal portions of the tubular bones are affected, leading to a characteristic radiographic pattern of bone sclerosis. Orbital involvement is not infrequent and is manifested by exophthalmos and periorbital xanthomatous lesions, with associated visual problems. This case report documents imaging and pathologic findings in a patient with ECD with extensive orbital involvement.