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RT Journal Article
SR Electronic
T1 Erdheim-Chester Disease: MR Imaging, Anatomic, and Histopathologic Correlation of Orbital Involvement
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 627
OP 630
VO 25
IS 4
A1 de Abreu, Marcelo R.
A1 Chung, Christine B.
A1 Biswal, Sandip
A1 Haghighi, Parvis
A1 Hesselink, John
A1 Resnick, Donald
YR 2004
UL http://www.ajnr.org/content/25/4/627.abstract
AB Summary: Erdheim-Chester disease (ECD) is a rare form of histiocytosis of unknown origin characterized by tissue infiltration by lipid-laden histiocytes. Typically, the diaphyseal and metaphyseal portions of the tubular bones are affected, leading to a characteristic radiographic pattern of bone sclerosis. Orbital involvement is not infrequent and is manifested by exophthalmos and periorbital xanthomatous lesions, with associated visual problems. This case report documents imaging and pathologic findings in a patient with ECD with extensive orbital involvement.