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RT Journal Article
SR Electronic
T1 Familial Amyloid Polyneuropathy: Hypertrophy of Ligaments Supporting the Spinal Cord
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 1599
OP 1602
VO 25
IS 9
A1 Kitajima, Mika
A1 Korogi, Yukunori
A1 Yamura, Masayuki
A1 Ikushima, Ichiro
A1 Hayashida, Yoshiko
A1 Ando, Yukio
A1 Uchino, Makoto
A1 Yamashita, Yasuyuki
YR 2004
UL http://www.ajnr.org/content/25/9/1599.abstract
AB Summary: We describe characteristic spinal MR findings of two cases of familial amyloid polyneuropathy (FAP). Both cases showed leptomeningeal enhancement on contrast-enhanced T1-weighted image. In addition, three-dimensional constructive interference in steady-state imaging demonstrated thickening of the ligaments, other connective tissues within the spinal canal, dura matter, and dorsal nerve roots. These findings in FAP are felt to represent amyloid deposition.