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PT  - JOURNAL ARTICLE
AU  - Bucek, Robert A.
AU  - Reiter, Markus
AU  - Dirisamer, Albert
AU  - Haumer, Markus
AU  - Fritz, Angelika
AU  - Minar, Erich
AU  - Lammer, Johannes
TI  - Three-Dimensional Color Doppler Sonography in Carotid Artery Stenosis
DP  - 2003 Aug 01
TA  - American Journal of Neuroradiology
PG  - 1294--1299
VI  - 24
IP  - 7
4099  - http://www.ajnr.org/content/24/7/1294.short
4100  - http://www.ajnr.org/content/24/7/1294.full
SO  - Am. J. Neuroradiol.2003 Aug 01; 24
AB  - BACKGROUND AND PURPOSE: Color Doppler sonography (CDS) suffers from such disadvantages as high interobserver variability and problems with data presentation and storage. We therefore performed a prospective trial to assess the role of three-dimensional CDS (3D-CDS) in the evaluation of internal carotid artery stenosis (ICAS).METHODS: We included 32 consecutive patients with sonographically verified ICAS (30–99%) and 16 asymptomatic volunteers. All underwent CDS and 3D-CDS, and 23 patients also underwent intraarterial angiography. The sensitivity, specificity, positive predictive value, and negative predictive value for the detection of high-grade ICAS were analyzed by three blinded readers, who also graded the percentage of ICAS.RESULTS: CDS revealed 14 patients with mild to moderate ICAS and 18 patients with high-grade ICAS. Mean sensitivity of 3D-CDS was 81.5%, mean specificity was 98.9%, mean positive predictive value was 97.9%, and mean negative predictive value was 89.9%. 3D-CDS correlated significantly with CDS (mean r = 0.85; P &amp;lt; .001) and angiography (mean r = 0.57; P = .01).CONCLUSION: 3D-CDS findings correlate with those obtained by CDS and angiography; 3D-CDS also offers excellent interobserver correlation, positive predictive value, and specificity, approaching 100% for the detection of high-grade ICAS.