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RT Journal Article
SR Electronic
T1 MR Imaging and Diffusion-Weighted Imaging Changes in Metronidazole (Flagyl)–Induced Cerebellar Toxicity
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 1615
OP 1617
VO 24
IS 8
A1 Heaney, Conor J.
A1 Campeau, Norbert G.
A1 Lindell, E. Paul
YR 2003
UL http://www.ajnr.org/content/24/8/1615.abstract
AB Summary: We describe a case demonstrating reversible MR imaging findings, including diffusion-weighted imaging changes in association with metronidazole (Flagyl) toxicity. The diagnosis of metronidazole toxicity was made clinically and supported by the MR imaging findings. Quantitative apparent diffusion coefficient (ADC) maps demonstrated edema with associated increased ADC values within the dentate nuclei of the cerebellum on initial imaging. Follow-up imaging performed 8 weeks after cessation of metronidazole therapy demonstrated resolution of imaging findings, including diffusion changes.