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PT  - JOURNAL ARTICLE
AU  - Lee, N.J.
AU  - Chung, M.S.
AU  - Jung, S.C.
AU  - Kim, H.S.
AU  - Choi, C.-G.
AU  - Kim, S.J.
AU  - Lee, D.H.
AU  - Suh, D.C.
AU  - Kwon, S.U.
AU  - Kang, D.-W.
AU  - Kim, J.S.
TI  - Comparison of High-Resolution MR Imaging and Digital Subtraction Angiography for the Characterization and Diagnosis of Intracranial Artery Disease
AID  - 10.3174/ajnr.A4950
DP  - 2016 Dec 01
TA  - American Journal of Neuroradiology
PG  - 2245--2250
VI  - 37
IP  - 12
4099  - http://www.ajnr.org/content/37/12/2245.short
4100  - http://www.ajnr.org/content/37/12/2245.full
SO  - Am. J. Neuroradiol.2016 Dec 01; 37
AB  - BACKGROUND AND PURPOSE: High-resolution MR imaging has recently been introduced as a promising diagnostic modality in intracranial artery disease. Our aim was to compare high-resolution MR imaging with digital subtraction angiography for the characterization and diagnosis of various intracranial artery diseases.MATERIALS AND METHODS: Thirty-seven patients who had undergone both high-resolution MR imaging and DSA for intracranial artery disease were enrolled in our study (August 2011 to April 2014). The time interval between the high-resolution MR imaging and DSA was within 1 month. The degree of stenosis and the minimal luminal diameter were independently measured by 2 observers in both DSA and high-resolution MR imaging, and the results were compared. Two observers independently diagnosed intracranial artery diseases on DSA and high-resolution MR imaging. The time interval between the diagnoses on DSA and high-resolution MR imaging was 2 weeks. Interobserver diagnostic agreement for each technique and intermodality diagnostic agreement for each observer were acquired.RESULTS: High-resolution MR imaging showed moderate-to-excellent agreement (interclass correlation coefficient = 0.892–0.949; κ = 0.548–0.614) and significant correlations (R = 0.766–892) with DSA on the degree of stenosis and minimal luminal diameter. The interobserver diagnostic agreement was good for DSA (κ = 0.643) and excellent for high-resolution MR imaging (κ = 0.818). The intermodality diagnostic agreement was good (κ = 0.704) for observer 1 and moderate (κ = 0.579) for observer 2, respectively.CONCLUSIONS: High-resolution MR imaging may be an imaging method comparable with DSA for the characterization and diagnosis of various intracranial artery diseases.HR-MRhigh-resolution MR imagingICADintracranial artery diseaseICCinterclass correlation coefficient