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PT  - JOURNAL ARTICLE
AU  - Tomura, N.
AU  - Ito, Y.
AU  - Matsuoka, H.
AU  - Saginoya, T.
AU  - Numazawa, S.-i.
AU  - Mizuno, Y.
AU  - Watanabe, K.
TI  - PET Findings of Intramedullary Tumors of the Spinal Cord Using [&lt;sup&gt;18&lt;/sup&gt;F] FDG and [&lt;sup&gt;11&lt;/sup&gt;C] Methionine
AID  - 10.3174/ajnr.A3374
DP  - 2013 Jun 01
TA  - American Journal of Neuroradiology
PG  - 1278--1283
VI  - 34
IP  - 6
4099  - http://www.ajnr.org/content/34/6/1278.short
4100  - http://www.ajnr.org/content/34/6/1278.full
SO  - Am. J. Neuroradiol.2013 Jun 01; 34
AB  - BACKGROUND AND PURPOSE: Only a few reports on intramedullary tumors of the spinal cord using PET have been published. We report findings of PET by using [18F] fluorodeoxyglucose and [11C] methionine and discuss the usefulness of the findings in patients with intramedullary tumors of the spinal cord. MATERIALS AND METHODS: PET/CT was performed in 9 patients with intramedullary tumors of the spinal cord: Six had ependymomas, 1 had an anaplastic astrocytoma, 1 had a hemangioblastoma, and 1 had a cavernous angioma. The maximum standardized uptake value of the tumor was measured and compared with pathologic findings. RESULTS: The SUVmax of FDG and MET in a case of anaplastic astrocytoma was high. The SUVmax of FDG and MET was relatively high in 4 of 6 cases of ependymoma (excluding myxopapillary ependymomas). A case of hemangioblastoma showed decreased uptake of both FDG and MET (SUVmax = 2.0 and 1.4, respectively). Three cases with hemorrhage (1 case of ependymoma, 1 case of cellular ependymoma, and 1 case of cavernous angioma) showed a relatively increased uptake of FDG. CONCLUSIONS: Both FDG and MET accumulated to a large degree in an anaplastic astrocytoma and accumulated in ependymomas (excluding a myxopapillary ependymoma). FDG can accumulate in tumors with hemorrhage. More investigation of a larger number of patients is required to evaluate the diagnostic value of PET with FDG and MET for imaging intramedullary tumors of the spinal cord. [11C]carbon 11[18F]fluorine 18FDGfluorodeoxyglucoseMET11C methionineSUVmaxmaximum standardized uptake value