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RT Journal Article
SR Electronic
T1 PET Findings of Intramedullary Tumors of the Spinal Cord Using [18F] FDG and [11C] Methionine
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 1278
OP 1283
DO 10.3174/ajnr.A3374
VO 34
IS 6
A1 Tomura, N.
A1 Ito, Y.
A1 Matsuoka, H.
A1 Saginoya, T.
A1 Numazawa, S.-i.
A1 Mizuno, Y.
A1 Watanabe, K.
YR 2013
UL http://www.ajnr.org/content/34/6/1278.abstract
AB BACKGROUND AND PURPOSE: Only a few reports on intramedullary tumors of the spinal cord using PET have been published. We report findings of PET by using [18F] fluorodeoxyglucose and [11C] methionine and discuss the usefulness of the findings in patients with intramedullary tumors of the spinal cord. MATERIALS AND METHODS: PET/CT was performed in 9 patients with intramedullary tumors of the spinal cord: Six had ependymomas, 1 had an anaplastic astrocytoma, 1 had a hemangioblastoma, and 1 had a cavernous angioma. The maximum standardized uptake value of the tumor was measured and compared with pathologic findings. RESULTS: The SUVmax of FDG and MET in a case of anaplastic astrocytoma was high. The SUVmax of FDG and MET was relatively high in 4 of 6 cases of ependymoma (excluding myxopapillary ependymomas). A case of hemangioblastoma showed decreased uptake of both FDG and MET (SUVmax = 2.0 and 1.4, respectively). Three cases with hemorrhage (1 case of ependymoma, 1 case of cellular ependymoma, and 1 case of cavernous angioma) showed a relatively increased uptake of FDG. CONCLUSIONS: Both FDG and MET accumulated to a large degree in an anaplastic astrocytoma and accumulated in ependymomas (excluding a myxopapillary ependymoma). FDG can accumulate in tumors with hemorrhage. More investigation of a larger number of patients is required to evaluate the diagnostic value of PET with FDG and MET for imaging intramedullary tumors of the spinal cord. [11C]carbon 11[18F]fluorine 18FDGfluorodeoxyglucoseMET11C methionineSUVmaxmaximum standardized uptake value