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RT Journal Article
SR Electronic
T1 Neuroimaging of Rapidly Progressive Dementias, Part 1: Neurodegenerative Etiologies
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 418
OP 423
DO 10.3174/ajnr.A3454
VO 35
IS 3
A1 Degnan, A.J.
A1 Levy, L.M.
YR 2014
UL http://www.ajnr.org/content/35/3/418.abstract
AB SUMMARY: Most dementias begin insidiously, developing slowly and generally occurring in the elderly age group. The so-called rapidly progressive dementias constitute a different, diverse collection of conditions, many of which are reversible or treatable. For this reason, prompt identification and assessment of acute and subacute forms of dementia are critical to effective treatment. Numerous other entities within this category of presenile rapid-onset dementias are untreatable such as the prion-related diseases. Neuroimaging aids in the diagnosis and evaluation of many of these rapidly progressive dementias, which include myriad conditions ranging from variations of more common neurodegenerative dementias, such as Alzheimer disease, dementia with Lewy bodies, and frontotemporal dementia; infectious-related dementias such as acquired immune deficiency syndrome dementia; autoimmune and malignancy-related conditions; to toxic and metabolic forms of encephalopathy. This first of a 2-part review will specifically address the ability of MR imaging and ancillary neuroimaging strategies to support the diagnostic evaluation of rapidly progressive dementias due to neurodegenerative causes. ADAlzheimer diseaseCBDcorticobasal degenerationDLBdementia with Lewy bodiesHDHuntington diseaseMSAmultiple-system atrophyPSPprogressive supranuclear palsy