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PT  - JOURNAL ARTICLE
AU  - LeMay, Marjorie
TI  - &lt;em&gt;Review&lt;/em&gt;. Radiologic Changes of the Aging Brain and Skull
DP  - 1984 May 01
TA  - American Journal of Neuroradiology
PG  - 269--275
VI  - 5
IP  - 3
4099  - http://www.ajnr.org/content/5/3/269.short
4100  - http://www.ajnr.org/content/5/3/269.full
SO  - Am. J. Neuroradiol.1984 May 01; 5
AB  - Computed tomographic (CT) studies during life reveal the involutionary changes in the brain found in postmortem studies. Beginning about the fourth decade, gradual widening of the third ventricle, sylvian and interhemispheric fissures, superficial sulci, and basal cisterns occurs. Enlargement of the lateral ventricles is most striking after the sixth decade of life. Regression of the brain with aging is a normal process. There is marked individual variation in the degree of involutional changes; not all lives are identical, and the longer the life span the less predictable one would expect the involutionary changes to be.