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PT  - JOURNAL ARTICLE
AU  - Caroff, J.
AU  - Mihalea, C.
AU  - Klisch, J.
AU  - Strasilla, C.
AU  - Berlis, A.
AU  - Patankar, T.
AU  - Weber, W.
AU  - Behme, D.
AU  - Jacobsen, E.A.
AU  - Liebig, T.
AU  - Prothmann, S.
AU  - Cognard, C.
AU  - Finkenzeller, T.
AU  - Moret, J.
AU  - Spelle, L.
TI  - Single-Layer WEBs: Intrasaccular Flow Disrupters for Aneurysm Treatment—Feasibility Results from a European Study
AID  - 10.3174/ajnr.A4369
DP  - 2015 Oct 01
TA  - American Journal of Neuroradiology
PG  - 1942--1946
VI  - 36
IP  - 10
4099  - http://www.ajnr.org/content/36/10/1942.short
4100  - http://www.ajnr.org/content/36/10/1942.full
SO  - Am. J. Neuroradiol.2015 Oct 01; 36
AB  - BACKGROUND AND PURPOSE: The safety and efficiency of the dual-layer Woven EndoBridge (WEB) device has already been published. However, this international multicenter study sought to evaluate the safety of single-layer devices, which are the newest generation of the WEB intrasaccular flow-disrupter family. They have been designed to offer smaller-sized devices with a lower profile to optimize navigability and delivery, which may, in turn, broaden their range of use.MATERIALS AND METHODS: Data from all consecutive patients treated with a single-layer WEB device, in 10 European centers from June 2013 to May 2014 were included. Clinical presentations, technical details, intra- and perioperative complications, and outcomes at discharge were recorded. Clinical and angiographic data at last follow-up were also analyzed when available.RESULTS: Ninety patients with 98 WEB-treated aneurysms were included in this study. In 93 cases (95%), WEB placement was possible. Complete occlusion at the end of the procedure was obtained in 26 instances (26%). Additional treatment during the procedure (coiling and/or stent placement) was necessary in 12 cases (12.7%). Procedure-related complications occurred in 13 cases, leading to permanent neurologic deficits in 4 patients (4.4%). Early vascular imaging follow-up data were available for 44 patients (57%), with an average time interval of 3.3 months. Treatment-related morbidity and mortality rates at last follow-up were 2.2% and 1.1%, respectively.CONCLUSIONS: In this study, the feasibility and safety of the single-layer WEB device was comparable with that of the double-layer. However, further studies are needed to evaluate long-term efficacies.DLdual-layerWEBWoven EndoBridgeSLsingle-layerSLSsingle-layer sphere.