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PT  - JOURNAL ARTICLE
AU  - Miki, S.
AU  - Hayashi, N.
AU  - Masutani, Y.
AU  - Nomura, Y.
AU  - Yoshikawa, T.
AU  - Hanaoka, S.
AU  - Nemoto, M.
AU  - Ohtomo, K.
TI  - Computer-Assisted Detection of Cerebral Aneurysms in MR Angiography in a Routine Image-Reading Environment: Effects on Diagnosis by Radiologists
AID  - 10.3174/ajnr.A4671
DP  - 2016 Jun 01
TA  - American Journal of Neuroradiology
PG  - 1038--1043
VI  - 37
IP  - 6
4099  - http://www.ajnr.org/content/37/6/1038.short
4100  - http://www.ajnr.org/content/37/6/1038.full
SO  - Am. J. Neuroradiol.2016 Jun 01; 37
AB  - BACKGROUND AND PURPOSE: Experiences with computer-assisted detection of cerebral aneurysms in diagnosis by radiologists in real-life clinical environments have not been reported. The purpose of this study was to evaluate the usefulness of computer-assisted detection in a routine reading environment.MATERIALS AND METHODS: During 39 months in a routine clinical practice environment, 2701 MR angiograms were each read by 2 radiologists by using a computer-assisted detection system. Initial interpretation was independently made without using the detection system, followed by a possible alteration of diagnosis after referring to the lesion candidate output from the system. We used the final consensus of the 2 radiologists as the reference standard. The sensitivity and specificity of radiologists before and after seeing the lesion candidates were evaluated by aneurysm- and patient-based analyses.RESULTS: The use of the computer-assisted detection system increased the number of detected aneurysms by 9.3% (from 258 to 282). Aneurysm-based analysis revealed that the apparent sensitivity of the radiologists&#039; diagnoses made without and with the detection system was 64% and 69%, respectively. The detection system presented 82% of the aneurysms. The detection system more frequently benefited radiologists than being detrimental.CONCLUSIONS: Routine integration of computer-assisted detection with MR angiography for cerebral aneurysms is feasible, and radiologists can detect a number of additional cerebral aneurysms by using the detection system without a substantial decrease in their specificity. The low confidence of radiologists in the system may limit its usefulness.CADcomputer-assisted detectionFPfalse-positiveTPtrue-positive