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PT  - JOURNAL ARTICLE
AU  - Trinh, Ba-Chinh
AU  - Melhem, Elias R.
AU  - Barker, Peter B.
TI  - Multi-slice Proton MR Spectroscopy and Diffusion-weighted Imaging in Methylmalonic Acidemia: Report of Two Cases and Review of the Literature
DP  - 2001 May 01
TA  - American Journal of Neuroradiology
PG  - 831--833
VI  - 22
IP  - 5
4099  - http://www.ajnr.org/content/22/5/831.short
4100  - http://www.ajnr.org/content/22/5/831.full
SO  - Am. J. Neuroradiol.2001 May 01; 22
AB  - Summary: Methylmalonic acidemia is an inborn disorder of amino acid metabolism that commonly presents with neurologic deficits. We present the results of multi-slice proton MR spectroscopy and diffusion-weighted imaging of the brain in two patients with methylmalonic acidemia. The findings consisted of restricted diffusion and elevated lactate in the globi pallidi, compatible with acute infarction (patient 1) and elevated lactate in CSF (patient 2).