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RT Journal Article
SR Electronic
T1 Multi-slice Proton MR Spectroscopy and Diffusion-weighted Imaging in Methylmalonic Acidemia: Report of Two Cases and Review of the Literature
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 831
OP 833
VO 22
IS 5
A1 Trinh, Ba-Chinh
A1 Melhem, Elias R.
A1 Barker, Peter B.
YR 2001
UL http://www.ajnr.org/content/22/5/831.abstract
AB Summary: Methylmalonic acidemia is an inborn disorder of amino acid metabolism that commonly presents with neurologic deficits. We present the results of multi-slice proton MR spectroscopy and diffusion-weighted imaging of the brain in two patients with methylmalonic acidemia. The findings consisted of restricted diffusion and elevated lactate in the globi pallidi, compatible with acute infarction (patient 1) and elevated lactate in CSF (patient 2).