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PT  - JOURNAL ARTICLE
AU  - Rollins, Nancy
AU  - Joglar, Jeanne
AU  - Perlman, Jeffery
TI  - Coexistent Holoprosencephaly and Chiari II Malformation
DP  - 1999 Oct 01
TA  - American Journal of Neuroradiology
PG  - 1678--1681
VI  - 20
IP  - 9
4099  - http://www.ajnr.org/content/20/9/1678.short
4100  - http://www.ajnr.org/content/20/9/1678.full
SO  - Am. J. Neuroradiol.1999 Oct 01; 20
AB  - Summary: Chiari II malformations and holoprosencephaly have been considered to be brain malformations that differ with respect to teratogenic insult, embryologic mechanism, and morphology. We herein describe coexistent Chiari II malformation and holoprosencephaly that occurred in a viable infant. A review of the literature regarding Chiari II malformations and holoprosencephaly suggests that a disturbance to the mesenchyme in early embryologic life may be the cause of both malformations.