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PT  - JOURNAL ARTICLE
AU  - Miyazawa, Nobuhiko
AU  - Uchida, Mikito
AU  - Fukamachi, Akira
AU  - Fukasawa, Isao
AU  - Sasaki, Hideo
AU  - Nukui, Hideaki
TI  - Xenon Contrast-Enhanced CT Imaging of Supratentorial Hypoperfusion in Patients with Brain Stem Infarction
DP  - 1999 Nov 01
TA  - American Journal of Neuroradiology
PG  - 1858--1862
VI  - 20
IP  - 10
4099  - http://www.ajnr.org/content/20/10/1858.short
4100  - http://www.ajnr.org/content/20/10/1858.full
SO  - Am. J. Neuroradiol.1999 Nov 01; 20
AB  - BACKGROUND AND PURPOSE: The characteristics of hypoperfusion in the supratentorial region of patients with brain stem infarction are unclear. We investigated the relationships between the presence of hypoperfusion and the location, number, and size of the infarcts with xenon contrast-enhanced CT.METHODS: One hundred five patients with brain stem infarction detected by MR imaging underwent xenon contrast-enhanced CT to measure the regional CBF (rCBF) in the frontal, temporal, parietal, and occipital regions and in the putamen and thalamus. A decrease of more than 10% from the mean rCBF value for normal individuals was considered to indicate hypoperfusion.RESULTS: Thirty-six patients had supratentorial hypoperfusion. The mean rCBF values (measured in mL/100 g/minute) were as follows: frontal region, 36.2 ± 5.1 (−14.8%, n = 28); parietal region, 42.3 ± 4.7 (−19.1%, n = 29); temporal region, 41.5 ± 2.8 (−12.6%, n = 12); and thalamus, 50.1 ± 3.2 (−19.6%, n = 7). Supratentorial hypoperfusion was associated with pontine infarction in 33 patients (upper pons in 15, middle pons in 18, and lower pons in seven), midbrain infarction in two, and medulla infarction in one. Twenty-three patients had infarcts that were larger than 5 mm, and 11 had infarcts that were 2 to 5 mm. Only two had infarcts that were smaller than 2 mm. Seven patients each had one infarct, 13 each had two, and 16 each had three.CONCLUSION: Supratentorial hypoperfusion was associated with larger infarcts, with more infarcts, and with pontine infarction.