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RT Journal Article
SR Electronic
T1 Dysgenesis of the Internal Carotid ArteryAssociated with Transsphenoidal Encephalocele:A Neural Crest Syndrome?
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 1154
OP 1157
VO 20
IS 6
A1 Blustajn, Jerry
A1 Netchine, Irène
A1 Frédy, Daniel
A1 Bakouche, Pierre
A1 Piekarski, Jean Daniel
A1 Meder, Jean François
YR 1999
UL http://www.ajnr.org/content/20/6/1154.abstract
AB Summary: We describe two original cases of internal carotid artery dysgenesis associated with a malformative spectrum, which includes transsphenoidal encephalocele, optic nerve coloboma, hypopituitarism, and hypertelorism. Cephalic neural crest cells migrate to various regions in the head and neck where they contribute to the development of structures as diverse as the anterior skull base, the walls of the craniofacial arteries, the forebrain, and the face. Data suggest that the link between these rare malformations is abnormal neural crest development.