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PT  - JOURNAL ARTICLE
AU  - Willoch, Frode
AU  - Tölle, Thomas Rudolf
AU  - Wester, Hans Jürgen
AU  - Munz, Frank
AU  - Petzold, Axel
AU  - Schwaiger, Markus
AU  - Conrad, Bastian
AU  - Bartenstein, Peter
TI  - Central Pain after Pontine Infarction Is Associated with Changes in Opioid Receptor Binding: A PET Study with &lt;sup&gt;11&lt;/sup&gt;C-Diprenorphine
DP  - 1999 Apr 01
TA  - American Journal of Neuroradiology
PG  - 686--690
VI  - 20
IP  - 4
4099  - http://www.ajnr.org/content/20/4/686.short
4100  - http://www.ajnr.org/content/20/4/686.full
SO  - Am. J. Neuroradiol.1999 Apr 01; 20
AB  - Summary: Using 18F-fluorodeoxyglucose and 11C-diprenorphine positron emission tomography (PET), we investigated alterations in glucose metabolism and opioid receptor binding in a patient with central poststroke pain, which developed after a small pontine hemorrhagic infarction. In comparison with normal databases, reduced 11C-diprenorphine binding was more accentuated than the hypometabolism on the lateral cortical surface contralateral to the symptoms, and a differential abnormal distribution between the tracers was seen in pain-related central structures. These results show that 11C-diprenorphine PET provides unique information for the understanding of central poststroke pain.