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PT  - JOURNAL ARTICLE
AU  - Jäger, Hans Rolf
AU  - Waldman, Adam D
AU  - Benton, Christopher
AU  - Fox, Nicholas
AU  - Rees, Jeremy
TI  - Differential Chemosensitivity of Tumor Components in a Malignant Oligodendroglioma: Assessment with Diffusion-Weighted, Perfusion-Weighted, and Serial Volumetric MR Imaging
DP  - 2005 Feb 01
TA  - American Journal of Neuroradiology
PG  - 274--278
VI  - 26
IP  - 2
4099  - http://www.ajnr.org/content/26/2/274.short
4100  - http://www.ajnr.org/content/26/2/274.full
SO  - Am. J. Neuroradiol.2005 Feb 01; 26
AB  - Summary: We report the case of malignant oligodendroglioma in a 36-year-old man who underwent diffusion-weighted, perfusion-weighted, and volumetric MR imaging before and after PCV (procarbazine, CCNU, vincristine) chemotherapy. The tumor regions exhibiting a low apparent diffusion coefficient and increased relative cerebral blood volume showed a marked response to chemotherapy and dramatic decrease in volume, whereas the remaining tumor regions showed little change. Diffusion-weighted and perfusion-weighted MR imaging may be helpful in predicting chemosensitivity of glial tumors.