1naresh<pre>Array
(
    [urn:ac.highwire.org:guest:identity] => Array
        (
            [runtime-id] => urn:ac.highwire.org:guest:identity
            [type] => guest
            [service-id] => ajnr-ac.highwire.org
            [access-type] => Controlled
            [privilege] => Array
                (
                    [urn:ac.highwire.org:guest:privilege] => Array
                        (
                            [runtime-id] => urn:ac.highwire.org:guest:privilege
                            [type] => privilege-set
                            [privilege-set] => GUEST
                        )

                )

            [credentials] => Array
                (
                    [method] => guest
                )

        )

)
1naresh<pre>Array
(
    [urn:ac.highwire.org:guest:identity] => Array
        (
            [runtime-id] => urn:ac.highwire.org:guest:identity
            [type] => guest
            [service-id] => ajnr-ac.highwire.org
            [access-type] => FreeToRead
            [privilege] => Array
                (
                    [urn:ac.highwire.org:guest:privilege] => Array
                        (
                            [runtime-id] => urn:ac.highwire.org:guest:privilege
                            [type] => privilege-set
                            [privilege-set] => GUEST
                        )

                )

            [credentials] => Array
                (
                    [method] => guest
                )

        )

)
PT  - JOURNAL ARTICLE
AU  - Rocca, Maria A.
AU  - Mezzapesa, Domenico M.
AU  - Ghezzi, Angelo
AU  - Falini, Andrea
AU  - Martinelli, Vittorio
AU  - Scotti, Giuseppe
AU  - Comi, Giancarlo
AU  - Filippi, Massimo
TI  - A Widespread Pattern of Cortical Activations in Patients at Presentation with Clinically Isolated Symptoms Is Associated with Evolution to Definite Multiple Sclerosis
DP  - 2005 May 01
TA  - American Journal of Neuroradiology
PG  - 1136--1139
VI  - 26
IP  - 5
4099  - http://www.ajnr.org/content/26/5/1136.short
4100  - http://www.ajnr.org/content/26/5/1136.full
SO  - Am. J. Neuroradiol.2005 May 01; 26
AB  - BACKGROUND AND PURPOSE: Movement-associated cortical changes have been detected at the earlier clinical stage multiple sclerosis. Our purpose was to assess whether different patterns of cortical recruitment are associated with the short-term evolution of definite multiple sclerosis (MS).METHODS: We followed for 1 year a group of patients with clinically isolated syndromes (CISs) suggestive of MS and compared the baseline movement-associated patterns of cortical activations between those patients with and those without evolution to definite MS.RESULTS: Those patients in whom MS did not evolve had more significant activations of several areas part of the “classic” motor network; those who went on to develop MS had more significant activations of several regions in the frontal, parietal, temporal, and occipital lobes.CONCLUSION: In CIS patients, the extent of early cortical reorganization following tissue injury might be a factor associated with a different disease evolution.