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PT  - JOURNAL ARTICLE
AU  - Katz, B H
AU  - Quencer, R M
AU  - Hinks, R S
TI  - Comparison of gradient-recalled-echo and T2-weighted spin-echo pulse sequences in intramedullary spinal lesions.
DP  - 1989 Jul 01
TA  - American Journal of Neuroradiology
PG  - 815--822
VI  - 10
IP  - 4
4099  - http://www.ajnr.org/content/10/4/815.short
4100  - http://www.ajnr.org/content/10/4/815.full
SO  - Am. J. Neuroradiol.1989 Jul 01; 10
AB  - Nineteen consecutive patients with spinal intramedullary lesions were studied on a 1.5-T system to compare the quality of T2-weighted spin-echo and gradient-recalled-echo (GRE) pulse sequences. Direct comparisons were made in the sagittal and/or axial planes. Twenty-four studies were performed in the 19 patients. The gradient echoes were usually performed at 300/14 (TR/TE) with a flip angle of 10 degrees. Although no significant diagnostic differences were noted in the sagittal plane, there was a distinct anatomic advantage for GRE imaging over spin-echo imaging in the axial plane. This is believed to be the result of CSF time-of-flight effects in the slice-select direction, which are not compensated for by flow-compensating gradients on the spin-echo images, but which are insignificant in the GRE sequence used in this study. Pathology was seen equally well or better on GRE in 79% (19/24) of the sequences. In the other five cases, the spin-echo image showed a brighter intramedullary signal than that seen on GRE, although GRE showed the lesion in all cases. Our results indicate that properly optimized GRE imaging on a high-field-strength system can replace spin-echo imaging in the spine when intramedullary disease is suspected and that the benefits of GRE are most striking in the axial plane.