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RT Journal Article
SR Electronic
T1 Meningeal dissemination of retinoblastoma: CT findings in eight patients.
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 983
OP 986
VO 11
IS 5
A1 Meli, F J
A1 Boccaleri, C A
A1 Manzitti, J
A1 Lylyk, P
YR 1990
UL http://www.ajnr.org/content/11/5/983.abstract
AB Thirty-seven patients with retinoblastoma were evaluated prospectively by clinical examination, lumbar puncture, and CT. Eight (22%) of the 37 were found to have meningeal dissemination. The tumor was bilateral in three patients. Two cases showed no CT signs of local recurrence. Headache, nausea/vomiting, and restlessness were the most common symptoms. CT scans in these patients showed diffuse meningeal contrast enhancement, nodular masses, ependymal-subependymal enhancement, and ventricular dilatation. Our series of eight patients with meningeal spread illustrates a considerable range of dissemination patterns referable to retinoblastoma. One case illustrated the CT finding of multiple epidural metastases.