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PT  - JOURNAL ARTICLE
AU  - van Amerongen, M.J.
AU  - Boogaarts, H.D.
AU  - de Vries, J.
AU  - Verbeek, A.L.M.
AU  - Meijer, F.J.A.
AU  - Prokop, M.
AU  - Bartels, R.H.M.A.
TI  - MRA Versus DSA for Follow-Up of Coiled Intracranial Aneurysms: A Meta-Analysis
AID  - 10.3174/ajnr.A3700
DP  - 2013 Sep 05
TA  - American Journal of Neuroradiology
4099  - http://www.ajnr.org/content/early/2013/09/05/ajnr.A3700.short
4100  - http://www.ajnr.org/content/early/2013/09/05/ajnr.A3700.full
AB  - SUMMARY: MR angiography is proposed as a safer and less expensive alternative to the reference standard, DSA, in the follow-up of intracranial aneurysms treated with endovascular coil occlusion. We performed a systematic review and meta-analysis to evaluate the accuracy of TOF-MRA and contrast-enhanced MRA in detecting residual flow in the follow-up of coiled intracranial aneurysms. Literature was reviewed through the PubMed, Cochrane, and EMBASE data bases. In comparison with DSA, the sensitivity of TOF-MRA was 86% (95% CI: 82–89%), with a specificity of 84% (95% CI: 81–88%), for the detection of any recurrent flow. For contrast-enhanced MRA, the sensitivity and specificity were 86% (95% CI: 82–89%) and 89% (95% CI: 85–92%), respectively. Both TOF-MRA and contrast-enhanced MRA are shown to be highly accurate for detection of any recanalization in intracranial aneurysms treated with endovascular coil occlusion. Abbreviations CEcontrast-enhancedGRADEgrades of recommendation, assessment, development, and evaluationSROCsummary receiver operating characteristic