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RT Journal Article
SR Electronic
T1 Spontaneous Lateral Sphenoid Cephaloceles: Anatomic Factors Contributing to Pathogenesis and Proposed Classification
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
DO 10.3174/ajnr.A3744
A1 Settecase, F.
A1 Harnsberger, H.R.
A1 Michel, M.A.
A1 Chapman, P.
A1 Glastonbury, C.M.
YR 2013
UL http://www.ajnr.org/content/early/2013/10/03/ajnr.A3744.abstract
AB SUMMARY: Spontaneous lateral sphenoid cephaloceles arise from bony defects in the lateral sphenoid, in the absence of predisposing factors such as trauma, surgery, mass, or congenital skull base malformation. We reviewed CT and MR imaging findings and clinical data of 26 patients with spontaneous lateral sphenoid cephaloceles to better understand anatomic contributions to pathogenesis, varying clinical and imaging manifestations, and descriptive terminology. Two types of spontaneous lateral sphenoid cephaloceles were identified. In 15 of 26 patients, a type 1 spontaneous lateral sphenoid cephalocele was noted, herniating into a pneumatized lateral recess of the sphenoid sinus, and typically presenting with CSF leak and/or headache. In 11 of 26 patients, a type 2 spontaneous lateral sphenoid cephalocele was noted, isolated to the greater sphenoid wing without extension into the sphenoid sinus, presenting with seizures, headaches, meningitis, cranial neuropathy, or detected incidentally. All patients had sphenoid arachnoid pits, and 61% of patients had an empty or partially empty sella, suggesting that altered CSF dynamics may play a role in their genesis. Abbreviations AbAGsaberrant arachnoid granulationsGWSgreater wing of the sphenoidIIHidiopathic intracranial hypertensionSLSCspontaneous lateral sphenoid cephaloceleSSsphenoid sinus