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PT  - JOURNAL ARTICLE
AU  - Gupta, A.C.
AU  - Chandra, R.V.
AU  - Yoo, A.J.
AU  - Leslie-Mazwi, T.M.
AU  - Bell, D.L.
AU  - Mehta, B.P.
AU  - Vanderboom, T.L.
AU  - Rabinov, J.D.
AU  - Larvie, M.
AU  - Hirsch, J.A.
TI  - Safety and Effectiveness of Sacroplasty: A Large Single-Center Experience
AID  - 10.3174/ajnr.A4027
DP  - 2014 Jul 10
TA  - American Journal of Neuroradiology
4099  - http://www.ajnr.org/content/early/2014/07/10/ajnr.A4027.short
4100  - http://www.ajnr.org/content/early/2014/07/10/ajnr.A4027.full
AB  - BACKGROUND AND PURPOSE: Sacral insufficiency fractures are a common cause of severe low back pain and immobilization in patients with osteoporosis or cancer. Current practice guideline recommendations range from analgesia and physical therapy to resection with surgical fixation. We sought to assess the safety and effectiveness of sacroplasty, an emerging minimally invasive treatment. MATERIALS AND METHODS: We performed a retrospective review of institutional databases for percutaneous sacroplasty performed between January 2004 and September 2013. Demographic and procedural data and pre- and posttreatment Visual Analog Scale, Functional Mobility Scale, and Analgesic Scale scores were reviewed. Overall response was rated by using a 4-point scale (1, complete resolution of pain; 2, improvement of pain; 3, no change; 4, worsened pain) assessed at short-term follow-up. RESULTS: Fifty-three patients were included; most (83%) were female. Fracture etiology was cancer-related (55%), osteoporotic insufficiency (30%), and minor trauma (15%). No major complication or procedure-related morbidity occurred. There were statistically significant decreases in the Visual Analog Scale (P &amp;lt; .001), Functional Mobility Scale (P &amp;lt; .001), and Analgesic Scale scores (P &amp;lt; .01) in 27 patients with recorded data: pretreatment Visual Analog Scale (median [interquartile range], 9.0 [8.0–10.0]); Functional Mobility Scale, 3.0 (2.0–3.0); and Analgesic Scale scores, 3.0 (3.0–4.0) were reduced to 3.0 (0.0–5.8), 1.0 (0.25–2.8), and 3.0 (2.0–3.8) posttreatment. When we used the overall 4-point score at a mean of 27 days, 93% (n = 45) reported complete resolution or improvement in overall pain. CONCLUSIONS: In this single-center cohort, sacroplasty was a safe and effective procedure. There were significant short-term gains in pain relief, increased mobility, and decreased dependence on pain medication. Abbreviations ASAnalgesic ScaleFMSFunctional Mobility ScalePMMApolymethylmethacrylateVASVisual Analog Scale