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RT Journal Article
SR Electronic
T1 MR assessment of pituitary gland morphology in healthy volunteers: age- and gender-related differences.
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 1295
OP 1299
VO 13
IS 5
A1 Doraiswamy, P M
A1 Potts, J M
A1 Axelson, D A
A1 Husain, M M
A1 Lurie, S N
A1 Na, C
A1 Escalona, P R
A1 McDonald, W M
A1 Figiel, G S
A1 Ellinwood, E H
YR 1992
UL http://www.ajnr.org/content/13/5/1295.abstract
AB PURPOSE AND METHODS High-field MR images at 1.5 T were used to characterize the effects of age and gender on pituitary size and shape in a sample of 71 adult volunteers (40 females), aged 21 to 82 years.FINDINGS For all subjects, age was inversely correlated with pituitary height (r = -.43, P less than .0002) and cross-sectional area (r = -.35, P less than .0028). Age-specific gender differences were also present in pituitary height and area. A convex upper pituitary margin was more common in females (P = .002) and younger subjects (P = .009).CONCLUSIONS This study confirms that aging is accompanied by gender-specific changes in pituitary size and shape, and provides normative data that may facilitate evaluation of the pituitary gland in neuroendocrine disorders.