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PT  - JOURNAL ARTICLE
AU  - Elolf, E.
AU  - Bockermann, V.
AU  - Gringel, T.
AU  - Knauth, M.
AU  - Dechent, P.
AU  - Helms, G.
TI  - Improved Visibility of the Subthalamic Nucleus on High-Resolution Stereotactic MR Imaging by Added Susceptibility (T2*) Contrast Using Multiple Gradient Echoes
AID  - 10.3174/ajnr.A0527
DP  - 2007 Jun 01
TA  - American Journal of Neuroradiology
PG  - 1093--1094
VI  - 28
IP  - 6
4099  - http://www.ajnr.org/content/28/6/1093.short
4100  - http://www.ajnr.org/content/28/6/1093.full
SO  - Am. J. Neuroradiol.2007 Jun 01; 28
AB  - SUMMARY: Reliable identification of the subthalamic nucleus (STN) is a critical step in deep brain stimulation for Parkinson disease but difficult on T1-weighted stereotactic MR imaging. By simultaneous imaging of multiple gradient echoes, susceptibility contrast is added to conventional T1-weighted high-resolution MR image. Thus, the visibility of the STN is enhanced on a second co-localized dataset by exploiting the sensitivity of the T2*-relaxation to local iron deposits. The feasibility is underpinned by quantitative measurements on healthy adults.