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RT Journal Article
SR Electronic
T1 Improved Visibility of the Subthalamic Nucleus on High-Resolution Stereotactic MR Imaging by Added Susceptibility (T2*) Contrast Using Multiple Gradient Echoes
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 1093
OP 1094
DO 10.3174/ajnr.A0527
VO 28
IS 6
A1 Elolf, E.
A1 Bockermann, V.
A1 Gringel, T.
A1 Knauth, M.
A1 Dechent, P.
A1 Helms, G.
YR 2007
UL http://www.ajnr.org/content/28/6/1093.abstract
AB SUMMARY: Reliable identification of the subthalamic nucleus (STN) is a critical step in deep brain stimulation for Parkinson disease but difficult on T1-weighted stereotactic MR imaging. By simultaneous imaging of multiple gradient echoes, susceptibility contrast is added to conventional T1-weighted high-resolution MR image. Thus, the visibility of the STN is enhanced on a second co-localized dataset by exploiting the sensitivity of the T2*-relaxation to local iron deposits. The feasibility is underpinned by quantitative measurements on healthy adults.