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PT  - JOURNAL ARTICLE
AU  - Sakai, Y.
AU  - Kira, R.
AU  - Torisu, H.
AU  - Ihara, K.
AU  - Yoshiura, T.
AU  - Hara, T.
TI  - Persistent Diffusion Abnormalities in the Brain Stem of Three Children with Mitochondrial Diseases
DP  - 2006 Oct 01
TA  - American Journal of Neuroradiology
PG  - 1924--1926
VI  - 27
IP  - 9
4099  - http://www.ajnr.org/content/27/9/1924.short
4100  - http://www.ajnr.org/content/27/9/1924.full
SO  - Am. J. Neuroradiol.2006 Oct 01; 27
AB  - SUMMARY: We report 2 children (patients 1 and 2) with Kearns-Sayre syndrome and 1 (patient 3) with Leigh syndrome, who underwent serial diffusion-weighted MR imaging (DWI) studies for 2.8 (patient 1), 4.2 (patient 2), and 1.0 years (patient 3). The DWI revealed the persistent hyperintense signals in the pontine and mesencephalic tegmenta. The apparent diffusion coefficient in the affected regions remained constantly low, suggesting that cytotoxic edema and spongiform degenerations may compose these brain stem lesions.