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PT  - JOURNAL ARTICLE
AU  - Xian, J.
AU  - Xu, X.
AU  - Wang, Z.
AU  - Yang, B.
AU  - Li, B.
AU  - Man, F.
AU  - Chen, Q.
AU  - Shi, J.
AU  - Zhang, Y.
TI  - MR Imaging Findings of the Uveal Schwannoma
AID  - 10.3174/ajnr.A1467
DP  - 2009 Apr 01
TA  - American Journal of Neuroradiology
PG  - 769--773
VI  - 30
IP  - 4
4099  - http://www.ajnr.org/content/30/4/769.short
4100  - http://www.ajnr.org/content/30/4/769.full
SO  - Am. J. Neuroradiol.2009 Apr 01; 30
AB  - BACKGROUND AND PURPOSE: Uveal schwannoma is a rare benign neoplastic proliferation of pure Schwann cells. The purpose of this study was to describe MR imaging features of uveal schwannoma.MATERIALS AND METHODS: MR images in 6 female patients with uveal schwannoma confirmed by pathologic examination were retrospectively reviewed. MR imaging was performed in all 6 patients, with postcontrast T1-weighted imaging (T1WI) completed in all 6 patients and dynamic contrast-enhanced MR imaging, in 5. MR imaging findings of the tumor were evaluated with emphasis on the location, size, shape, margin, signal intensity, and pattern of enhancement.RESULTS: The lesions appeared as solitary well-defined ovoid masses in the ciliochoroidal region in 5 patients and in the choroid in 1. With respect to the vitreous body, uveal schwannoma was hyperintense on T1WI spin-echo (SE) images in all 6 patients. The tumors were hypointense to the vitreous body on fast SE (FSE) T2-weighted images (T2WI) in 4 patients and isointense in 1. However, with respect to the brain, uveal schwannoma demonstrated isointensity on T1WI SE images in all 6 patients, isointensity on FSE T2WI images in 5 patients, and hyperintensity on T2WI SE images in 1. On postcontrast T1WI images, 3 patients showed markedly heterogeneous enhancement, and 3 showed markedly homogeneous enhancement.CONCLUSIONS: Uveal schwannoma should be included in the differential diagnosis when an oval isointense mass relative to brain is seen in the ciliochoroidal region.